Abstract
Retinoblastoma is a malignant pediatric eye tumor that is highly curable if the disease remains intraocular; its cure rate and sight preservation rate exceeds 90% in developed countries in part because of early diagnosis and access to adequate treatment. Retinoblastoma accounts for approximately 3% of all pediatric malignancies, and approximately two-thirds of patients present with unilateral disease, while one-third have bilateral involvement. Patients with unilateral disease are usually treated with enucleation, while few also receive adjuvant chemotherapy or radiation therapy. Management of bilateral patients is much more challenging since eye salvage and vision preservation must also be considered. The management of these cases includes chemotherapy and careful, intensive use of focal treatments. Such a regimen therefore requires the cooperation of a highly specialized, multidisciplinary team.
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Acknowledgments
United States
Eugene Helveston, M.D.
Ophthalmologist-in-Chief
ORBIS International
Al L. Ueltschi
Chairman
ORBIS International & FlightSafety International, Inc.
Lynda Smallwood
Senior Manager, Cyber-Sight
ORBIS International
Matthew W. Wilson, M.D., FACS
Professor of Ophthalmology
UT Hamilton Eye Institute
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
James C. Fleming, M.D., FACS
Philip M. Lewis Professor of Ophthalmology
Director of the Orbit Center
Hamilton Eye Institute
UT Health Science Center
Memphis, TN
Raul C. Ribeiro, M.D.
Director, Leukemia/Lymphoma
Director, International Outreach
St. Jude Children’s Research Hospital, Memphis, TN
Judith A. Wilimas, M.D.
Medical Director
Referring Physicians Office and Domestic Affiliate Program
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
Carlos Rodriguez-Galindo, M.D.
Pediatric Oncologist
Dana-Farber Cancer Institute/
Children’s Hospital Boston
Boston, MA
Ibrahim Qaddoumi, M.D., M.S.
Director of Telemedicine
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
George Vélez, DHAc, M.B.A., CFAAMA
Administrative Director
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
Gaston K. Rivera, M.D.
Medical Director, Chile Program
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
Yuri Quintana, Ph.D.
Director, Education and Informatics
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
Richard O’Brien
Educational Technologies Administrator
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
Jorge I. Calzada, M.D.
Ophthalmologist
Hamilton Eye Institute
UT Health Science Center
Memphis, TN
Sandra Luna-Fineman, M.D.
Pediatric Hematologist/Oncologist
California Pacific Med Center-Davies
San Francisco, CA
The Richard T. and Josephine Arkwright Foundation
New York, NY
Robert B. Carter, M.B.A.
Executive Vice President & Chief Information Officer
FedEx Corporation
Memphis, TN
Blanca Phillips
Coordinator and Ophthalmic Photographer
UT Hamilton Eye Institute
International Outreach Program
St. Jude Children’s Research Hospital
Memphis, TN
Lee A. Thompson, M.A.
Publication Specialist
Hamilton Eye Institute
UT Health Science Center
Memphis, TN
Guatemala
Federico Antillon-Klussman, M.D.
Pediatric Hematologist/Oncologist & Medical Director
Hospital de Oncología Pediátrica
Guatemala City, Guatemala
Margarita Barnoya, M.D.
Ophthalmologist
Hospital de Oncología Pediátrica
Guatemala City, Guatemala
Mauricio Castellanos, M.D.
Pediatric Hematologist/Oncologist
Hospital de Oncología Pediátrica
Guatemala City, Guatemala
Guillermo Chantada, M.D.
Pediatric Hematologist/Oncologist
Department of Hemato-Oncology, Hospital JP Garrahan
Buenos Aires, Argentina
Panama
Ernesto Calvo, M.D.
Ophthalmologist
Clinica de Ojos Orillac-Calvo
Panama, Republic of Panama
Maria Sabina Ahchu, M.D.
Pediatric Hematologist/Oncologist
Hospital del Niño de Panamá
Panama, Republic of Panama
J. Thomas Ford
Trustee, Board Member
Director, and Past President Programa Niños Sanos: Niños Felices
Panama, Republic of Panama
Honduras
Ligia Fu, M.D.
Pediatric Hematologist/Oncologist & Medical Director
Hospital Escuela Materno Infantil
Tegucigalpa, Honduras
Carlos Maldonado, M.D.
Ophthalmologist
Hospital Escuela Materno Infantil
Tegucigalpa, Honduras
Lilia Lopez, M.D.
Ophthalmologist
Hospital Escuela Materno Infantil
Tegucigalpa, Honduras
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Haik, B.G. (2012). Retinoblastoma Management: Connecting Institutions with Telemedicine. In: Yogesan, K., Goldschmidt, L., Cuadros, J. (eds) Digital Teleretinal Screening. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-25810-7_19
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