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Development of a Process Chain for Nanoparticles Production by Yeasts

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Metal Nanoparticles in Microbiology

Abstract

Advances in nanotechnology and the constant quest for new materials are the driving forces behind the development of alternative and original nanoparticle synthetic pathways. The biotechnological approach, based on the process of biomineralization, exploits the effectiveness and flexibility of biological systems to synthesize reproducible nanoparticles with well-defined size and structure. The knowledge, regarding physiology, technological clarity and the vast scale-up potential, defines yeasts as an attractive object–producer of nanoparticles, with industrial significance.

The present chapter describes the main technological steps in a biotechnological process, including isolation of commercially relevant yeast strains; cultivation strategies, resulting in high yield; downstream protocols, ensuring products with high purity and quality; and final product characterization. All these procedures form an integrated process chain for the production of nanoparticles by yeasts.

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Acknowledgments

The authors would like to express their gratitude to Prof. Dr. Ursula Obst, Dr. Gerald Brenner-Weiss, Dipl.-Ing. Frank Kirschhöfer from Institute for Functional Interfaces, Dr. Patrick Kölsch and Silvia Andraschko from Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Germany, for their support, suggestions and immeasurable proficiency in conducting the analytical experiments.

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  1. Department of Bioprocess Engineering, Institute of Process Engineering in Life Sciences, Karlsruhe Institute of Technology, Fritz-Haber-Weg 2, Build. 30.44, Karlsruhe, Germany

    Nikolay Krumov & Clemens Posten

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  1. Nikolay Krumov
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  2. Clemens Posten
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Correspondence to Nikolay Krumov .

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  1. , Dept. Biotechnology, SGB Amravati University, Amravati, 444602, Maharashtra, India

    Mahendra Rai

  2. Instituto de Quimica, Lab. Biological Chemistry, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil

    Nelson Duran

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Krumov, N., Posten, C. (2011). Development of a Process Chain for Nanoparticles Production by Yeasts. In: Rai, M., Duran, N. (eds) Metal Nanoparticles in Microbiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18312-6_9

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