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The Diversity of Soluble Di-iron Monooxygenases with Bioremediation Applications

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Advances in Applied Bioremediation

Part of the book series: Soil Biology ((SOILBIOL,volume 17))

Abstract

Pollution with organic compounds (especially xenobiotics) is a significant ­problem of industrial societies. Treatment of waste streams to remove potential pollutants or remediation of contaminated sites can be achieved by exploiting the degradative capacity of bacteria. Among the most important of the enzymes used by bacteria in degradation of organic compounds are oxygenases. These enzymes catalyse the addition of oxygen atoms into organic compounds to produce alcohols, epoxides, etc. whose greater reactivity makes them substrates for a wider range of enzymes (Urlacher and Schmid 2006). The substrate range accommodated by the known oxygenases is enormous and for many organic pollutants, degradation pathways are initiated by oxygenases. This makes these enzymes applicable as fundamentally important enzymes to many bioremediation projects. They encompass a number of different protein families, utilizing distinct chemistries (Park 2007; Urlacher and Eiben 2006; van Beilen and Funhoff 2005; van Berkel et al. 2006; Wackett 2002).

This chapter focuses on one family of monoxygenases that have been termed the soluble di-iron monooxygenases (SDIMO), also termed bacterial multicomponent monooxygenases (BMM), that have wide applications in bioremediation (Leahy et al. 2003; Notomista et al. 2003). Recent advances in understanding of diversity in the SDIMOs are creating new opportunities for their effective use in bioremediation.

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Authors and Affiliations

  1. School of Molecular and Microbial Biosciences, The University of Sydney, NSW, Australia

    Andrew J. Holmes

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  1. Andrew J. Holmes
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Correspondence to Andrew J. Holmes .

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Editors and Affiliations

  1. Dept. Biology, University of Waterloo, University Avenue W. 200, Waterloo, N2L 3G1, Canada

    A. Singh

  2. Fac. Inter-Disciplinary &, University of Delhi, Benito Juarez Road, New Delhi, 110021, India

    Ramesh C. Kuhad

  3. Dept. Biology, University of Waterloo, University Avenue W. 200, Waterloo, N2L 3G1, Canada

    Owen P. Ward

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© 2009 Springer-Verlag Berlin Heidelberg

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Holmes, A.J. (2009). The Diversity of Soluble Di-iron Monooxygenases with Bioremediation Applications. In: Singh, A., Kuhad, R., Ward, O. (eds) Advances in Applied Bioremediation. Soil Biology, vol 17. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-89621-0_5

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