Skip to main content
SpringerLink
Log in

Lung Cancer

  • Chapter
  • First Online:
Comparative Interpretation of CT and Standard Radiography of the Chest

Part of the book series: Medical Radiology ((Med Radiol Diagn Imaging))

  • 2554 Accesses

Abstract

Lung cancer is one of the leading causes of cancer mortality in the world. In clinical practice, lung cancers are divided into non–small cell carcinoma (80% of cases) and small cell carcinoma (20% of cases) due to clinical distinction in presentation, metastatic diffusion, and therapy. Early diagnosis of lung cancer may be associated with better operability and prognosis. Chest X-ray (CXR) remains the most commonly performed test in diagnostic radiology. It is therefore of paramount importance for radiologists to be aware of the radiological presentation of lung cancer because it is often discovered when a CXR is obtained in a patient for another purpose and the frequency of missed lung cancer is high. Because there is a large spectrum of radiologic manifestations of lung cancer, detection of these findings is essential for proper patient management. To highlight the CXR presentation of lung carcinoma, correlations with computed tomography findings in coronal, axial, sagittal, virtual bronchoscopy, and three-dimensional imaging are presented in this chapter.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 279.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Bach PB, Jett JR, Pastorino U, Tockman MS, Swensen SJ, Begg CB (2007) Computed tomography screening and lung cancer outcomes. JAMA 297:953–961

    Article  PubMed  CAS  Google Scholar 

  • Beckett WS (1993) Epidemiology and etiology of lung cancer. Clin Chest Med 14:1–15

    PubMed  CAS  Google Scholar 

  • Beckles MA, Spiro SG, Colice GL, Rudd RM (2003) Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes. Chest 123(1 Suppl):97S–104S

    Article  PubMed  Google Scholar 

  • Berg CD, Aberle DR, National Lung Screening Trial Executive Committee. (2007) CT screening for lung cancer. N Engl J Med 356:743–744

    Article  PubMed  CAS  Google Scholar 

  • Brambilla E, Travis WD, Colby TV, Corrin B, Shimosato Y (2001) The new World Health Organization classification of lung tumours. Eur Respir J 18:1059–1068

    Article  PubMed  CAS  Google Scholar 

  • Brogdon BG, Kelsey CA, Moseley RD Jr (1983) Factors affecting perception of pulmonary lesions. Radiol Clin North Am 21:633–654

    PubMed  CAS  Google Scholar 

  • Bruzzi JF, Komaki R, Walsh GL, Truong MT, Gladish GW, Munden RF, Erasmus JJ (2008a) Imaging of non-small cell lung cancer of the superior sulcus: part 1: anatomy, clinical manifestations, and management. Radiographics 28:551–560

    Article  PubMed  Google Scholar 

  • Bruzzi JF, Komaki R, Walsh GL, Truong MT, Gladish GW, Munden RF, Erasmus JJ (2008b) Imaging of non-small cell lung cancer of the superior sulcus: part 2: initial staging and assessment of resectability and therapeutic response. Radiographics 28:561–572

    Article  PubMed  Google Scholar 

  • Byrd RB, Carr DT, Miller WE, Payne WS, Woolner LB (1969) Radiographic abnormalities in carcinoma of the lung as related to histological cell type. Thorax 24:573–575

    Article  PubMed  CAS  Google Scholar 

  • Chen JJ, White CS (2008) Use of CAD to evaluate lung cancer on chest radiography. J Thorac Imaging 23:93–96

    Article  PubMed  Google Scholar 

  • Chooi WK, Matthews S, Bull MJ, Morcos SK (2005) Multislice computed tomography in staging lung cancer: the role of multiplanar image reconstruction. J Comput Assist Tomogr 29:357–360

    Article  PubMed  Google Scholar 

  • Ferretti GR, Jankowski A, Rodière M, Brichon PY, Brambilla C, Lantuejoul S (2008) CT-guided biopsy of nonresolving focal air space consolidation. J Thorac Imaging 23:7–12

    Article  PubMed  Google Scholar 

  • Filderman AE, Shaw C, Matthay RA (1986) Lung cancer. Part I: Etiology, pathology, natural history, manifestations, and diagnostic techniques. Invest Radiol 21:80–90

    Article  PubMed  CAS  Google Scholar 

  • Fraser RG, Paré JAP (1999) Diagnosis of diseases of the chest. W.B. Saunders, Philadelphia

    Google Scholar 

  • Gould MK, Fletcher J, Iannettoni MD, Lynch WR, Midthun DE, Naidich DP, Ost DE (2007) Evaluation of patients with pulmonary nodules: when is it lung cancer?: ACCP evidence-based clinical practice guidelines (2nd edition). Chest 132:108S–130S

    Article  PubMed  Google Scholar 

  • Hansell DM, Amstrong P, Lynch DA, Page McAdams H (2005) Imaging of diseases of the chest. Elsevier Mosby, Philadelphia

    Google Scholar 

  • Heelan RT, Flehinger BJ, Melamed MR, Zaman MB, Perchick WB, Caravelli JF, Martini N (1984) Non-small-cell lung cancer: results of the New York screening program. Radiology 151:289–293

    PubMed  CAS  Google Scholar 

  • Heitzman ER (1977) Bronchogenic carcinoma: radiologic-pathologic correlations. Semin Roentgenol 12:165–173

    Article  PubMed  CAS  Google Scholar 

  • Henschke CI, McCauley DI, Yankelevitz DF, Naidich DP, McGuinness G, Miettinen OS, Libby DM, Pasmantier MW, Koizumi J, Altorki NK, Smith JP (1999) Early Lung Cancer Action Project: overall design and findings from baseline screening. Lancet 354(9173):99–105

    Article  PubMed  CAS  Google Scholar 

  • Hill CA (1982) “Tail” signs associated with pulmonary lesions: critical reappraisal. AJR Am J Roentgenol 139:311–316

    PubMed  CAS  Google Scholar 

  • Kim TH, Kim SJ, Ryu YH, Chung SY, Seo JS, Kim YJ, Choi BW, Lee SH, Cho SH (2006) Differential CT features of infectious pneumonia versus bronchioloalveolar carcinoma (BAC) mimicking pneumonia. Eur Radiol 16(8):1763–1768

    Article  PubMed  Google Scholar 

  • Kubik A, Parkin DM, Khlat M, Erban J, Polak J, Adamec M (1990) Lack of benefit from semi-annual screening for cancer of the lung: follow-up report of a randomized controlled trial on a population of high-risk males in Czechoslovakia. Int J Cancer 45:26–33

    Article  PubMed  CAS  Google Scholar 

  • Lee KS, Kim Y, Han J, Ko EJ, Park CK, Primack SL (1997) Bronchioloalveolar carcinoma: clinical, histopathologic, and radiologic findings. Radiographics 17:1345–1357

    PubMed  CAS  Google Scholar 

  • Leung AN, Müller NL, Miller RR (1990) CT in differential diagnosis of diffuse pleural disease. AJR Am J Roentgenol 154:487–492

    PubMed  CAS  Google Scholar 

  • Marcus PM, Bergstralh EJ, Fagerstrom RM, Williams DE, Fontana R, Taylor WF, Prorok PC (2000) Lung cancer mortality in the Mayo Lung Project: impact of extended follow-up. Natl Cancer Inst 92:1308–1316

    Article  CAS  Google Scholar 

  • McAdams HP, Samei E, Dobbins J, Tourassi GD, Ravin CE (2006) Recent advances in chest radiography. Radiology 241:663–683

    Article  PubMed  Google Scholar 

  • McLoud T, Swenson SJ (1999) Lung carcinoma. Clin Chest Med 20:697–713

    Article  PubMed  CAS  Google Scholar 

  • Muhm JR, Miller WE, Fontana RS, Sanderson DR, Uhlenhopp MA (1983) Lung cancer detected during a screening program using four-month chest radiographs. Radiology 148:609–615

    PubMed  CAS  Google Scholar 

  • Patz EF (2000) Imaging bronchogenic carcinoma. Chest 117:90–95

    Article  Google Scholar 

  • Pearlberg JL, Sandler MA, Beute GH et al (1987) Limitations of CT in evaluation of neoplasms involving chest wall. J Comput Assist Tomogr 11:290–293

    Article  PubMed  CAS  Google Scholar 

  • Pearlberg JL, Sandler MA, Lewis JW Jr et al (1988) Small-cell bronchogenic carcinoma: CT evaluation. AJR Am J Roentgenol 150:265–268

    PubMed  CAS  Google Scholar 

  • Rosado-de-Christenson ML, Templeton PA, Moran CA (1994) Bronchogenic carcinoma: radiologic-pathologic correlation. Radiographics 14:429–446

    PubMed  CAS  Google Scholar 

  • Samei E, Flynn MJ, Peterson E, Eyler WR (2003) Subtle lung nodules: influence of local anatomic variations on detection. Radiology 228:76–84

    Article  PubMed  Google Scholar 

  • Scagliotti G (2001) Symptoms, signs and staging of lung cancer. Eur Respir Mon 17:86–119

    Google Scholar 

  • Sider L (1990) Radiographic manifestations of primary bronchogenic carcinoma. Radiol Clin North Am 28:583–597

    PubMed  CAS  Google Scholar 

  • Sone S, Sakai F, Takashima S, Honda T, Yamanda T, Kubo K, Fukasaku K, Maruyama Y, Li F, Hasegawa M, Ito A, Yang Z (1997) Factors affecting the radiologic appearance of peripheral bronchogenic carcinomas. J Thorac Imaging 12:159–172

    Article  PubMed  CAS  Google Scholar 

  • Spiro SG, Gould MK, Colice GL (2007) Initial evaluation of the patient with lung cancer: symptoms, signs, laboratory tests, and paraneoplastic syndromes: ACCP evidenced-based clinical practice guidelines (2nd edition). Chest 132:149S–160S

    Article  PubMed  Google Scholar 

  • Swensen SJ, Jett JR, Hartman TE, Midthun DE, Mandrekar SJ, Hillman SL, Sykes AM, Aughenbaugh GL, Bungum AO, Allen KL (2005) CT screening for lung cancer: five-year prospective experience. Radiology 235:259–265

    Article  PubMed  Google Scholar 

  • Theros EG (1977) Varying manifestations of peripheral pulmonary neoplasms: a radiologic-pathologic correlative study. AJR Am J Roentgenol 128:893–914

    PubMed  CAS  Google Scholar 

  • Woodring JH (1988) Determining the cause of pulmonary atelectasis: a comparison of plain radiography and CT. AJR Am J Roentgenol 150:757–763

    PubMed  CAS  Google Scholar 

  • Yankelevitz D, Henschke CI (1997) Does 2-year stability imply pulmonary nodules are benign? AJR Am J Roentgenol 168:325–328

    PubMed  CAS  Google Scholar 

  • Zwirewich CV, Vedal S, Miller RR, Müller NL (1991) Solitary pulmonary nodule: high-resolution CT and radiologic-pathologic correlation. Radiology 179:469–476

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. CHU Grenoble, Clinique Universitaire de Radiologie et Imagerie Médicale, 38043, Grenoble cedex 09, France

    Gilbert R. Ferretti & Adrien Jankowski

  2. INSERM U 823, Institut A. Bonniot, Boulevard de la Chantourne, 38700, La Tronche, France

    Gilbert R. Ferretti & Adrien Jankowski

Authors
  1. Gilbert R. Ferretti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Adrien Jankowski
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gilbert R. Ferretti .

Editor information

Editors and Affiliations

  1. Clinique Saint Luc, Dept. Radiology, Université Catholique Louvain, avenue Hippocrate 10, Bruxelles, 1200, Belgium

    Emmanuel E. Coche

  2. Service Imagerie Médicale, CHU de Liège, Liège, 4000, Belgium

    Benoit Ghaye

  3. Academisch Ziekenhuis, Afd. Radiologie, Vrije Universiteit Brussel, Laarbeeklaan 101, Bruxelles, 1090, Belgium

    Johan de Mey

  4. Academisch Ziekenhuis, Afd. Radiologie, Universiteit Gent, De Pintelaan 185, Gent, 9000, Belgium

    Philippe Duyck

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Berlin Heidelberg

About this chapter

Cite this chapter

Ferretti, G.R., Jankowski, A. (2011). Lung Cancer. In: Coche, E., Ghaye, B., de Mey, J., Duyck, P. (eds) Comparative Interpretation of CT and Standard Radiography of the Chest. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-79942-9_17

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-79942-9_17

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-79941-2

  • Online ISBN: 978-3-540-79942-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation