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Cancer of the Anal Canal

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Radiation Oncology

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Anal cancer is a rare type of gastrointestinal malignancy. Over 80% of anal cancers are of squamous origin and arise from the squamous epithelium of the anal canal and perianal area. Recent evidence has demonstrated that the incidence of squamous cell carcinoma of anal cancer increases in immunocompromised patients. Approximately 10% are adenocarcinoma arising from the glandular mucosa of the upper anal canal or anal glands. Other malignancies of the anal canal, such as melanoma, sarcoma, and lymphoma, are exceedingly rare. Surgery has limited application in the treatment of squamous cell carcinoma of the anal canal. Radiation therapy plays a major role in the treatment of anal cancer, and concurrent chemoradiation therapy is the standard treatment for most cases of locally advanced disease.

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Author information

Authors and Affiliations

  1. Department of Radiation Oncology, The 6th Hospital of Jiao Tong University, 600 Yi Shan Road, Shanghai, 200233, P. R. China

    Qing Zhang MD

  2. Department of Radiation Oncology, Baptist Hospital, 8900 North Kendall Drive, Miami, FL, 33176, USA

    Andre A. Abitbol MD

Authors
  1. Qing Zhang MD
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  2. Andre A. Abitbol MD
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Editor information

Editors and Affiliations

  1. Department of Radiation Oncology National University Cancer Institute of Singapore National University Health System, National University of Singapore, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore

    Jiade J. Lu MD, MBA (Associate Professor and Consultant and Distinguished Clinical Professor) (Associate Professor and Consultant and Distinguished Clinical Professor)

  2. Department of Radiation Oncology, Cancer Hospital of Fudan University, 270 Dong An Road, Shanghai, 200232, P.R. China

    Jiade J. Lu MD, MBA (Associate Professor and Consultant and Distinguished Clinical Professor) (Associate Professor and Consultant and Distinguished Clinical Professor)

  3. College of Medicine, Drexel University, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102-1192, USA

    Luther W. Brady MD (Hylda Cohn/American Cancer Society Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor) (Hylda Cohn/American Cancer Society Professor of Clinical Oncology, and Professor, Department of Radiation Oncology Distinguished University Professor)

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© 2008 Springer-Verlag Berlin Heidelberg

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Zhang, Q., Abitbol, A.A. (2008). Cancer of the Anal Canal. In: Lu, J.J., Brady, L.W. (eds) Radiation Oncology. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77385-6_17

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  • DOI: https://doi.org/10.1007/978-3-540-77385-6_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-77384-9

  • Online ISBN: 978-3-540-77385-6

  • eBook Packages: MedicineMedicine (R0)

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