Skip to main content

Sporotrichosis: An Emergent Disease

  • Chapter
Sporotrichosis

Abstract

In recent decades, the frequency of invasive fungal infections has increased steadily, resulting in considerable morbidity and mortality. The increasing number of fungal infections has significantly contributed to health-related costs. The outcome of an infection with a human-pathogenic fungus often depends on the immune status of the host organism. Patients with a weakened immune system are at high risk of developing a serious fungal infection. On the other hand, increased prescribing of antifungals has led to the emergence of resistant fungi, resulting in treatment challenges. Sporothrix complex is an environmental pathogenic fungus found worldwide in soil, plants, and decaying vegetables. It is the etiological agent of sporotrichosis in humans and several domestic animals. Sporotrichosis was a neglected disease; however, it is now considered an emergent disease and is causing concern for the health authorities of several tropical and subtropical countries such as Brazil, Mexico, and Peru. Over the past decade, the incidence of sporotrichosis has been on the rise, and currently different fungal genotypes may be closely associated with the virulence of this fungus. Some leisure and occupational activities, such as agriculture and floriculture, have been associated with transmission of the disease, but today it is considered an important zoonosis, particularly in Brazil. This chapter also presents cases of sporotrichosis reported worldwide to show a picture of this disease.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Addy JH (1992) Disseminated cutaneous sporotrichosis associated with anergic immuno-suppression due to miliary tuberculosis. West Afr J Med 11(3):216–220

    CAS  PubMed  Google Scholar 

  • Agarwal S, Gopal K, Umesh, Kumar B et al (2008) Sporotrichosis in Uttarakhand (India): a report of nine cases. Int J Dermatol 47(4):367–371

    Article  PubMed  Google Scholar 

  • Ajello L, Kaplan W (1969) A new variant of Sporothrix schenckii. Mykosen 12(11):633–644

    Article  CAS  PubMed  Google Scholar 

  • Alberici F, Paties CT, Lombardi G, Ajello L et al (1989) Sporothrix schenckii var lurei as the cause of sporotrichosis in Italy. Eur J Epidemiol 5(2):173–177

    Article  CAS  PubMed  Google Scholar 

  • Arenas R, Miller D, Campos-Macias P (2007) Epidemiological data and molecular characterization (mtDNA) of Sporothrix schenckii in 13 cases from Mexico. Int J Dermatol 46(2):177–179

    Google Scholar 

  • Arrillaga-Moncrieff I, Capilla J, Mayayo E, Marimon R et al (2009) Different virulence levels of the species of Sporothrix in a murine model. Clin Microbiol Infect 15:651–655

    Article  CAS  PubMed  Google Scholar 

  • Azogue E (1981) Esporotricosis cutanea en el departamento de Santa Cruz-Bolivia/Esporotricosis skin in the district Santa Cruz Cruz Bolivia. Bol Inf Cenetrop 7(1):48–52

    Google Scholar 

  • Barile F, Mastrolonardo M, Loconsole F, Rantuccio F (1993) Cutaneous sporotrichosis in the period 1978–1992 in the province of Bari, Apulia, Southern Italy. Mycoses 5–6:181–185

    Google Scholar 

  • Barros MB, Schubach TM, Galhardo MC, Schubach AO et al (2001) Sporotrichosis: na emergent zoonosis in Rio de Janeiro. Mem Inst Oswaldo Cruz 96:777–779

    Article  Google Scholar 

  • Barros MB, Schubach Ade O, do Valle AC et al (2004) Cat-transmitted sporotrichosis epidemic in Rio de Janeiro, Brazil: Description of a series of cases. Clin Infect Dis 38:529–535

    Article  PubMed  Google Scholar 

  • Barros MB, Schubach AO, Schubach TM, Wanke B et al (2008) An epidemic of sporotrichosis in Rio de Janeiro, Brazil: epidemiological aspects of a series of cases. Epidemiol Infect 136:1192–1196

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Betancourt O, Zaror L, Senn C (2013) Aislamiento de hongos filamentosos desde pelaje de gatos sin lesiones dermicas en Temuco, Chile. Revista Cientifica de la Facultad de Ciencias Veterinarias 23(5):380

    Google Scholar 

  • Bhutia PY, Gurung S, Yegneswaran PP, Pradhan J et al (2011) A case series and review of sporotrichosis in Sikkim. J Infect Dev Ctries 5(8):603–608

    PubMed  Google Scholar 

  • Black H, Taylor DE, Yeoman DM (1968) Sporotrichosis in New Zealand: a case report. N Z Med J 68(434):27–30

    CAS  PubMed  Google Scholar 

  • Bonifaz A, Saúl A, Paredes-Solis V, Fierro L et al (2007) Sporotrichosis in childhood: clinical and therapeutic experience in 25 patients. Pediatr Dermatol 24(4):369–372

    Article  PubMed  Google Scholar 

  • Borges TS, Rossi CN, Fedullo JD et al (2013) Isolation of Sporothrix schenckii from the claws of domestic cats (indoor and outdoor) and in captivity in São Paulo (Brazil). Mycopathologia 176:129–137

    Article  PubMed  Google Scholar 

  • Brown R, Weintroub D, Simpson M W (1947) Timber as a source of sporotrichosis infection. In: Proceedings of the Transvaal Mine Medical Officers' Association, Johanesburg pp. 5–38

    Google Scholar 

  • Bunce PE, Yang L, Chun S, Zhang SX et al (2012) Disseminated sporotrichosis in a patient with hairy cell leukemia treated with amphotericin B and posaconazole. Med Mycol 50:197–201

    Article  CAS  PubMed  Google Scholar 

  • Bustamante B, Campos PE (2001) Endemic sporotrichosis. Curr Opin Infect Dis 14(2):145–149

    Article  CAS  PubMed  Google Scholar 

  • Cafarchia C, Sasanelli M, Lia RP et al (2007) Lymphocutaneous and nasal sporotrichosis in a dog from Southern Italy: case report. Mycopathologia 163:75–79

    Article  PubMed  Google Scholar 

  • Calero C, Tapia A (1962) Two cases of sporotrichosis in the Isthmus of Panama. Am J Trop Med Hyg 11:676–677

    CAS  PubMed  Google Scholar 

  • Callens SF, Kitetele F, Lukun P et al (2006) Pulmonary Sporothrix schenckii infection in a HIV positive child. J Trop Pediatr 52(2):144–146

    Google Scholar 

  • Camacho E, León-Navarro I, Rodríguez-Brito S et al (2015) Molecular epidemiology of human sporotrichosis in Venezuela reveals high frequency of Sporothrix globosa. BMC Infect Dis 15(1):94

    Article  PubMed Central  PubMed  Google Scholar 

  • Campbell C (1965) A case of sporotrichosis occurring in Papua. Med J Aust 2(1):23

    CAS  PubMed  Google Scholar 

  • Carmichael JW (1962) Chrysosporium and some other aleuriosporic hyphomycetes. Can J Bot 40:1137–1173

    Article  Google Scholar 

  • Carod JF, Ramarozatovo L, Randrianasolo P et al (2007) Cutaneous sporotricosis in a Malagasy patient. Med Trop (Mars) 67(1):18

    CAS  Google Scholar 

  • Carr MM, Fielding JC, Sibbald G et al (1995) Sporotrichosis of the hand: an urban experience. J Hand Surg [Am] 20(1):66–70

    Article  CAS  Google Scholar 

  • Civila ES, Bonasse J, Conti-Díaz IA et al (2004) Importance of the direct fresh examination in the diagnosis of cutaneous sporotrichosis. Inter J Dermatol 43:808–810

    Article  Google Scholar 

  • Coles FB, Schuchat A, Hibbs JR et al (1992) A multistate outbreak of sporotrichosis associated with sphagnum moss. Am J Epidemiol 136:475–487

    CAS  PubMed  Google Scholar 

  • Conias S, Wilson P (1998) Epidemic cutaneous sporotrichosis: report of 16 cases in Queensland due to mouldy hay. Australas J Dermatol 39:34–37

    Article  CAS  PubMed  Google Scholar 

  • Conti Díaz IA (1989) Epidemiology of sporotrichosis in Latin America. Mycopathologia 108:113–116

    PubMed  Google Scholar 

  • Criseo G, Romeo O (2010) Ribosomal DNA sequencing and phylogenetic analysis of environmental Sporothrix schenckii strains: comparison with clinical isolates. Mycopathologia 169:351–358

    Article  CAS  PubMed  Google Scholar 

  • Criseo G, Malara G, Romeo O et al (2008) Lymphocutaneous sporotrichosis in an immunocompetent patient: a case report from extreme southern Italy. Mycopathologia 166(3):159–162

    Article  PubMed  Google Scholar 

  • Cruz R, Vieille P, Oschilewski D (2012) Sporothrix globosa isolation related to a case of lymphocutaneous sporotrichosis. Rev Chil Infectol 29(4):401–405

    Article  Google Scholar 

  • D’Alessio DJ, Leavens LJ, Strumpf GB et al (1965) An outbreak of sporotrichosis in Vermont associated with sphagnum moss as the source of infection. N Engl J Med 20(272):1054–1058

    Article  Google Scholar 

  • Dahl BA, Silberfarb PM, Sarosi GA et al (1971) Sporotrichosis in children. Report of an epidemic. JAMA 215:1980–1982

    Article  CAS  PubMed  Google Scholar 

  • Dalis JS, Kazeem HM, Kwaga JK et al (2014) Severe generalized skin lesions due to mixed infection with Sporothrix schenckii and Dermatophilus congolensisin a bull from Jos Nigeria. Vet Microbiol 172(3-4):475–478

    Article  CAS  PubMed  Google Scholar 

  • de Beer ZW, Harrington TC, Vismer HF et al (2003) Phylogeny of the Ophiostoma stenoceras-Sporothrix schenckii complex. Mycologia 95(3):434–441

    Article  PubMed  Google Scholar 

  • de Beurmann L, Gougerot H (1912) Les sporotrichoses. Felix Alcan, Paris

    Google Scholar 

  • de Hoog GS (1974) The genera Blastobotrys, Sporothrix, Calcarisporium and Calcarisporiella gen nov. Stud Mycol 7:1–119

    Google Scholar 

  • de Hoog GS, Guarro J, Gené J et al (2000) Atlas of clinical fungi, 2nd edn. Centraalbureau voor Schimmelcultures, Utrecht, The Netherlands

    Google Scholar 

  • de Lezcano LB, Di Martino B, Villalba J, Rodríguez M et al (2008) An unusual clinical presentation of fixed cutaneous sporotrichosis. Report of two cases. Rev Panam Infectol 10(3):45–47

    Google Scholar 

  • de Meyer EM, de Beer ZW, Summerbell RC et al (2008) Taxonomy and phylogeny of new wood- and soil-inhabiting Sporothrix species in the Ophiostoma stenoceras-Sporothrix schenckii complex. Mycologia 100:647–661

    Article  PubMed  Google Scholar 

  • Devi KR, Devi MU, Singh TN, Devi KS et al (2006) Emergence of sporotrichosis in Manipur. Indian J Med Microbiol 24(3):216–219

    CAS  PubMed  Google Scholar 

  • Dhingra D, Durrheim D, Porigneaux P (2015) Sporotrichosis outbreak and mould hay in NSW. Aust Fam Physician 44(4):217–221

    PubMed  Google Scholar 

  • Dias NM, Oliveira MME, Portela MA et al (2011) (2011) Sporotrichosis caused by Sporothrix mexicana. Portugal Emerg Infec Dis 17:1975–1976

    Article  Google Scholar 

  • Dixon DM, Salkin IF, Duncan RA et al (1991) Isolation and characterization of Sporothrix schenckii from clinical and environmental sources associated with the largest U.S epidemic of sporotrichosis. J Clin Microbiol 29(6):1106–1113

    PubMed Central  CAS  PubMed  Google Scholar 

  • Dooley DP, Bostic PS, Beckius ML (1997) Spook house sporotrichosis. A point-source outbreak of sporotrichosis associated with hay bale props in a Halloween haunted-house. Arch Intern Med 157:1885–1887

    Article  CAS  PubMed  Google Scholar 

  • Dunstan RW, Langham RF, Reimann KA et al (1986) Feline sporotrichosis: a report of five cases with transmission to humans. J Am Acad Dermatol 15(1):37–45

    Article  CAS  PubMed  Google Scholar 

  • El-Mofty AM, Nada M (1965) Sporotrichosis in Egypt. Br J Dermatol 77:357–364

    Article  CAS  PubMed  Google Scholar 

  • Epinosa-Texis A, Hernández-Hernandez F, Lavalle P et al (2001) Study of 50 patients with sporotrichosis. Clinical and laboratory assessment. Gac Med Mex 137(2):111–116

    Google Scholar 

  • Escaffi F, María José Benedetto B, Antonieta Podlipnik C, Sebastián (2010) Esporotricosis cutánea: revisión a propósito de un caso contraído en Chile/Cutaneous sporotrichosis: a Chilean case report. Rev Chil Dermatol 26(2):154–158

    Google Scholar 

  • Feeney KT, Arthur IH, Whittle AJ, Altman SA et al (2007) Outbreak of sporotrichosis, Western Australia. Emerg Infec Dis 13:1228–1231

    Article  Google Scholar 

  • Fernandes GF, dos Santos PO, Rodrigues AM et al (2013) Characterization of virulence profile, protein secretion and immunogenicity of different Sporothrix schenckii sensu stricto isolates compared with S. globosa and S. brasiliensis species. Virulence 4(3):1–9

    Article  Google Scholar 

  • Fernández-Silva F, Capilla J, Mayayo E et al (2012) Virulence of Sporothrix luriei in a murine model of disseminated infection. Mycopathologia 173(4):245–249

    Article  PubMed  Google Scholar 

  • Fleury RN, Taborda PR, Gupta AK et al (2001) Zoonotic sporotrichosis. Transmission to humans by infected domestic cat scratching: report of four cases in São Paulo. Brazil Int J Dermatol 40(5):318–322

    CAS  PubMed  Google Scholar 

  • Flores C, Ferrada L, De la Parra M (1982) Estudio micológico y experimental de un caso de esporotricosis. Bol Micol 1:39–42

    Google Scholar 

  • Freitas D, Migliano M, Zani Neto L (1956) Esporotricose—Observação de caso espontâneo em gato doméstico (F. catus). Rev Fac Med Vet Univ São Paulo 5(4):601–604

    Article  Google Scholar 

  • Freitas D, Moreno G, Saliba A et al (1965) Esporotricose em cães e gatos. Rev Fac Med Vet Univ São Paulo 7(2):381–387

    Article  Google Scholar 

  • Freitas DF, de Siqueira HB, do Valle AC et al (2012) Sporotrichosis in HIV-infected patients: report of 21 cases of endemic sporotrichosis in Rio de Janeiro, Brazil. Med Mycol 50:170–178

    Article  PubMed  Google Scholar 

  • Fujii H, Tanioka M, Yonezawa M et al (2008) A case of atypical sporotrichosis with multifocal cutaneous ulcers. Clin Exp Dermatol 33(2):135–138

    Article  CAS  PubMed  Google Scholar 

  • Ghosh A, Chakrabarti A, Sharma VK et al (1999) Sporotrichosis in Himachal Pradesh (North India). Trans R Soc Trop Med Hyg 93:41–45

    Article  CAS  PubMed  Google Scholar 

  • Gori S, Lupetti A, Moscato G et al (1997) Pulmonary sporotrichosis with hyphae in a human immunodeficiency virus-infected patient. A case report. Acta Cytol 41(2):519–521

    Article  CAS  PubMed  Google Scholar 

  • Gremião ID, Menezes RC, Schubach TM et al (2015) Feline sporotrichosis: epidemiological and clinical aspects. Med Mycol 53(1):15–21

    Article  PubMed  Google Scholar 

  • Gumaa SA (1978) Sporotrichosis in Sudan. Trans R Soc Trop Med Hyg 72(6):637–640

    Article  CAS  PubMed  Google Scholar 

  • Gurcan S, Konuk E, Kilic H et al (2007) Sporotrichosis, a disease rarely reported from Turkey, and an overview of Turkish literature. Mycoses 50:426–429

    Article  PubMed  Google Scholar 

  • Hajjeh R, McDonnell S, Reef S et al (1997) Outbreak of sporotrichosis among tree nursery workers. J Infect Dis 176:499–504

    Article  CAS  PubMed  Google Scholar 

  • Hawks GH (1955) Sporotrichosis Report of tree cases from Toronto. Can Med Assoc J 72:28–32

    PubMed Central  CAS  PubMed  Google Scholar 

  • Hektoen L, Perkins CF (1900) Refractory subcutaneous abscesses caused by Sporothrix schenckii. A new pathogenic fungus. J Exp Med 5:77–89

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Houh W, Chung SR, Ro BI (1995) Itraconazole in the treatment of sporotrichosis: a Korean experience. Trop Doct 25(3):107–109

    CAS  PubMed  Google Scholar 

  • Howard DH (1961) Dimorphism of Sporotrichum schenckii. J Bacteriol 81:464–469

    PubMed Central  CAS  PubMed  Google Scholar 

  • Inokuma D, Shibaki A, Shimizu H (2010) Two cases of cutaneous sporotrichosis in continental ⁄ microthermal climate zone: global warming alert? Clin Exp Dermatol 35:668–676

    Article  CAS  PubMed  Google Scholar 

  • Ishizaki H, Kawasaki M, Aoki M et al (2004) Mitochondrial DNA analysis of Sporothrix schenckii from China, Korea and Spain. Nihon Ishinkin Gakkai Zasshi 45(1):23–25

    Article  CAS  PubMed  Google Scholar 

  • Jacyk WK, Lawande RV, Tulpule SS (1981) Deep mycoses in West Africa: a report of 13 cases and review of the Nigerian literature. J Natl Med Assoc 73(3):251–256

    PubMed Central  CAS  PubMed  Google Scholar 

  • Jirásek L, Fragner P, Pavlásková I (1976) A case of epidermal sporotrichosis. Cesk Dermatol 51(3):162–167

    PubMed  Google Scholar 

  • Kazemi A, Razi A (2007) Sporotrichosis in Iran. Rev Iberoam Micol 24:38–40

    Article  PubMed  Google Scholar 

  • Kong X, Xiao T, Lin J et al (2006) Relationships among genotypes, virulence and clinical forms of Sporothrix schenckii infection. Clin Microbiol Infect 12(11):1077–1081

    Article  CAS  PubMed  Google Scholar 

  • Krempl-Lamprecht L (1978) Tropic-subtropic fungus infections in Germany. Hautarzt 29(1):17–21

    CAS  PubMed  Google Scholar 

  • Kusuhara M, Hachisuka H, Sasai Y (1988) Statistical survey of 150 cases with sporotrichosis. Mycopathologia 102:129–133

    Article  CAS  PubMed  Google Scholar 

  • Kwangsukstith C, Vanittanakom N, Khanjanasthiti P et al (1990) Cutaneous sporotrichosis in Thailand: first reported case. Mycoses 33(11-12):513–517

    CAS  PubMed  Google Scholar 

  • Laur WE, Posey RE, Waller JD (1979) A familial epidemic of cutaneous sporotrichosis occurring in north Texas. Cutis 23:205–208

    CAS  PubMed  Google Scholar 

  • Learmonth GE (1915) Observations on a Sporothrix bearing some resemblance to the Sporothrix beurmanni. Can Med Assoc J 5(1):32–38

    PubMed Central  CAS  PubMed  Google Scholar 

  • Lee H, Kim DY, Lee KH (2015) Deformity of the earlobe caused by fixed cutaneous sporotrichosis in a pediatric patient. Int J Dermatol 54(5):e187–e189

    Article  PubMed  Google Scholar 

  • Liu TT, Zhang K, Zhou X (2014) Molecular identification of Sporothrix clinical isolates in China. J Zhejiang Univ Sci B 15(1):100–108

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Lutz A, Splendore A (1907) On a mycosis observed in men and mice: Contribution to the knowledge of the so-called sporotrichosis. Revista Médica de São Paulo 21:443–450

    Google Scholar 

  • Lyon GM, Zurita S, Casquero J et al (2003) Population-based surveillance and a case-control study of risk factors for endemic lymphocutaneous sporotrichosis in Peru. Clin Infec Dis 36:34–39

    Article  CAS  Google Scholar 

  • Mackinnon JE (1972) Regional peculiarities of some deep mycoses. Mycopathol Mycol Appl 46:249–265

    Article  CAS  PubMed  Google Scholar 

  • Madrid H, Cano J, Gene J et al (2009) Sporothrix globosa, a pathogenic fungus with widespread geographical distribution. Rev Iberoam Micol 26(3):218–222

    Article  PubMed  Google Scholar 

  • Madrid H, Gené J, Cano J et al (2010) Sporothrix brunneoviolacea and Sporothrix dimorphospora, two new members of the Ophiostoma stenoceras-Sporothrix schenckii complex. Mycologia 102:1193–1203

    Article  CAS  PubMed  Google Scholar 

  • Madrid IM, Mattei AS, Fernandes CG et al (2012) Epidemiological Findings and Laboratory Evaluation of Sporotrichosis: A Description of 103 Cases in Cats and Dogs in Southern Brazil. Mycopathologia 173:265–273

    Article  PubMed  Google Scholar 

  • Magand F, Perrot JL, Cambazard F et al (2009) Sporotrichose cutanée autochtone française. Ann Dermatol Venereol 2009(136):273–275

    Article  Google Scholar 

  • Mahajan VK, Sharma NL, Sharma RC et al (2005) Cutaneous sporotrichosis in Himachal Pradesh, India. Mycoses 48:25–31

    Article  CAS  PubMed  Google Scholar 

  • Marimon R, Gené J, Cano J et al (2006) Molecular phylogeny of Sporothrix schenckii. J Clin Microbiol 44:3251–3256

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Marimon R, Cano J, Gené J et al (2007) Sporothrix brasiliensis, S. globosa, and S. mexicana, three new Sporothrix species of clinical interest. J Clin Microbiol 45:3198–3206

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  • Marimon R, Gené J, Cano J et al (2008) Sporothrix luriei: a rare fungus from clinical origin. Med Mycol 46:621–625

    Article  PubMed  Google Scholar 

  • Mata-Essayag S, Delgado A, Maria T, Colella MT et al (2013) Epidemiology of sporotrichosis in Venezuela. Int J Dermatol 52:974–980

    Article  PubMed  Google Scholar 

  • Matter SE, Bailey DM, Sexton DJ (1984) Immune deficiency presenting as disseminated sporotrichosis. J Okla State Med Assoc 77:114–117

    CAS  PubMed  Google Scholar 

  • Mayorga R, Cáceres A, Toriello et al (1979) Investigación de uma zona endemica de esporotricosis em La region de La Laguna de Ayarza, Guatemala. Bol Sanit Panam 87(1):20–34

    CAS  Google Scholar 

  • Mayorga-Rodriguez JA, Barba-Rubio J, Munõz-Estrada VF et al (1997) Sporotrichosis in Jalisco state: a clinical epidemiological study (1960±1996). Dermatol Rev Mex 41:105–108

    Google Scholar 

  • McCarty TP, Pappas PG (2014) The evolving epidemiology of sporotrichosis. Curr Fungal Infect Rep 8(4):255–261

    Article  Google Scholar 

  • Mehta KI, Sharma NL, Kanga AK et al (2007) Isolation of Sporothrix schenckii from the environmental sources of cutaneous sporotrichosis patients in Himachal Pradesh, India: results of a pilot study. Mycoses 50(6):496–501

    Article  PubMed  Google Scholar 

  • Mesa-Arango AC, Del Rocío R-MM, Pérez-Mejía A et al (2002) Phenotyping and genotyping of Sporothrix schenckii isolates according to geographic origin and clinical form of Sporotrichosis. J Clin Microbiol 40(8):3004–3011

    Article  PubMed Central  PubMed  Google Scholar 

  • Mora-Cabrera M, Alonso RA, Ulloa-Arvizu R et al (2001) Analysis of restriction profiles of mitochondrial DNA from Sporothrix schenckii. Med Mycol 39:439–444

    Article  CAS  PubMed  Google Scholar 

  • Morgado FN, Schubach AO, Barros MB et al (2011) The in situ inflammatory profile of lymphocutaneous and fixed forms of human sporotrichosis. Med Mycol 49(6):612–620

    PubMed  Google Scholar 

  • Muir DB, Pritchard RC (1984) Sporothrix schenckii—incidence in the Sydney region. Australas J Dermatol 25:27–28

    Article  CAS  PubMed  Google Scholar 

  • Nakamura Y, Sato H, Watanabe S et al (1996) Sporothrix schenckii isolated from a cat in Japan. Mycoses 39(3-4):125–128

    Article  CAS  PubMed  Google Scholar 

  • Negroni R, Maiolo E, Arechavala AI et al (2007) Problemas clínicos em Micologia Medica: problema n° 25. Rev Iberoam Micol 24:79–81

    Article  PubMed  Google Scholar 

  • Newton PN, Chung WH, Phetsouvanh R et al (2005) Sporotrichosis, Plain of Jars, Lao People's Democratic Republic. Emerg Infect Dis 11(9):1496–1497

    Article  PubMed Central  PubMed  Google Scholar 

  • Neyra E, Fonteyne PA, Swinne D et al (2005) Epidemiology of human sporotrichosis investigated by amplified fragment length polymorphism. J Clin Microbiol 43(3):1348–1352

    Article  PubMed Central  PubMed  Google Scholar 

  • Nusbaum BP, Nita Gulbas N, Horwitz N (1983) Sporotrichosis acquired from a cat. J Am Acad Dermatol 8:386–391

    Article  CAS  PubMed  Google Scholar 

  • Oda S, Kotani Y, Matsumura T (1964) Two cases of sporotrichosis in mie prefecture. Hifuka Kiyo 59:195–199

    CAS  PubMed  Google Scholar 

  • Ojeda T, Rodríguez-Pichardo A, Suárez AI (2011) Esporotricosis en la provincia de Sevilla (España) Carta científica. Enferm Infec Microbiol Clin 29(3):232–242

    Article  Google Scholar 

  • Oliveira MME, Almeida-Paes R, Muniz MM et al (2011) Phenotypic and molecular identification of Sporothrix isolates from an epidemic area of sporotrichosis in Brazil. Mycopathologia 172:257–267

    Article  PubMed  Google Scholar 

  • Oliveira MM, Almeida-Paes R, Gutierrez-Galhardo MC et al (2014) Molecular identification of the Sporothrix schenckii complex. Rev Iberoam Micol 31(1):2–6

    Google Scholar 

  • Pappas PG, Tellez I, Deep AE et al (2000) Sporotrichosis in Peru: Description of an Area of Hyperendemicity. Clin Infect Dis 30:65–70

    Article  CAS  PubMed  Google Scholar 

  • Pardo-Castello V, Trespalacios F (1959) Superficial and deep mycoses in Cuba: a report based on 1,174 cases. South Med J 52(1):7–15

    Article  CAS  PubMed  Google Scholar 

  • Park CH, Greer CL, Cook CB (1972) Cutaneous sporotrichosis: recent appearance in Northern Virginia. Am J Clin Pathol 57(1):23–26

    CAS  PubMed  Google Scholar 

  • Pereira SA, Menezes RC, Gremião ID et al (2011) Sensitivity of cytopathological examination in the diagnosis of feline sporotrichosis. J Feline Med Surg 13:220–223

    Article  PubMed  Google Scholar 

  • Pereira SA, Gremião ID, Kitada AA et al (2014) The epidemiologicals cenário of feline sporotrichosis in Rio de Janeiro, Stateof Rio de Janeiro, Brazil. Rev Soc Bras Med Trop 47(3):392–393

    Article  PubMed  Google Scholar 

  • Pérez-Fernández N, Jaka-Moreno A, de la Cabac I et al (2013) Nodular skin lesions in a patient from Nicaragua. Enferm Infecc Microbiol Clin 31(2):114–115

    Article  PubMed  Google Scholar 

  • Pérez-Morales L, Iglesias-López M, Quiñones-Cherta O et al (2014) Aislamiento microbiológico de Sporothrix schenckii en un paciente inmunodeprimido. Presentación de un caso. Medisur 12(4):662–669

    Google Scholar 

  • Pönnighaus M, Grosser S, Baum HP (2003) Sporotrichosis as the cause of a leg ulcer. Hautarzt 54(1):64–66

    PubMed  Google Scholar 

  • Powell KE, Taylor A, Phillips BJ et al (1978) Cutaneous sporotrichosis in forestry workers: epidemic due to contaminated sphagnum moss. JAMA 240:232–235

    Article  CAS  PubMed  Google Scholar 

  • Ramírez M, Andagua J, Lizárraga J et al (2011) Esporotricosis en pacientes que acuden a un centro medico de referencia en Abancay, Perú. Rev Peru Med Exp Salud Publica 28:508–512

    Article  Google Scholar 

  • Randhawa HS, Chand R, Mussa AY et al (2003) Sporotrichosis in India: First case in a Delhi resident and an update. Indian J Med Microbiol 21:12–16

    CAS  PubMed  Google Scholar 

  • Rippon JW (1988) Sporotrichosis. In: Rippon JW (ed) Medical Mycology. The Pathogenic Fungi and Pathogenic Actinomycetes, 3rd edn. WB Saunders, Philadelphia PA, pp 325–352

    Google Scholar 

  • Robinson CF, Orban TD (1951) A case of regional lymphatic sporotrichosis. Aust J Dermatol 1:142–144

    Article  CAS  PubMed  Google Scholar 

  • Rodrigues AM, Teixeira MM, Hoog G et al (2013a) Phylogenetic Analysis Reveals a High Prevalence of Sporothrix brasiliensis in Feline Sporotrichosis Outbreaks. PLoS Negl Trop Dis 7(6):1–14

    Google Scholar 

  • Rodrigues AM, de Hoog GS, Camargo ZP (2013b) Emergence of pathogenicity in the Sporothrix schenckii complex. Med Mycol 51(4):405–412

    Article  PubMed  Google Scholar 

  • Rodrigues AM, de Hoog GS, Zhang Y et al (2014) Emerging sporotrichosis is driven by clonal and recombinant Sporothrix species. Emerg Microbes Infect 3, e32

    Article  PubMed Central  PubMed  Google Scholar 

  • Roets F, de Beer ZW, Wingfield MJ et al (2008) Ophiostoma gemellus and Sporothrix variecibatus from mites infesting Protea in fructescences in South Africa. Mycologia 100:496–510

    Article  PubMed  Google Scholar 

  • Romero-Cabello R, Bonifaz A, Romero-Feregrino R et al (2011) Disseminated sporotrichosis BMJ Case Rep 25 doi: 10.1136/bcr.10.2010.3404

    Google Scholar 

  • Sánchez-Saldaña L, Galarza CM, Matos-Sánchez R (2009) Infecciones micóticas subcutáneas. Dermatología Peruana 19(4):362–387

    Google Scholar 

  • Schenck BR (1898) Refractory subcutaneous abscesses caused by a fungus possibly related to the sporotricha. Bull Johns Hopkins Hosp 9:286–290

    Google Scholar 

  • Schubach TM, de Oliveira SA, dos Reis RS et al (2002) Sporothrix schenckii isolated from domestic cats with and without sporotrichosis in Rio de Janeiro, Brazil. Mycopathologia 153:83–86

    Article  PubMed  Google Scholar 

  • Schubach TM, Schubach A, Okamoto T et al (2004) Evaluation of an epidemic of sporotrichosis in cats: 347 cases (1998-2001). J Am Vet Med Assoc 224:1623–1629

    Article  PubMed  Google Scholar 

  • Silva MBT, Costa MMM, Torres CCS (2012) Urban sporotrichosis: a neglected epidemic in Rio de Janeiro, Brazil. Cad Saúde Pública Rio de Janeiro 28(10):1867

    Article  Google Scholar 

  • Sivagnanam S, Bannan AM, Chen SC et al (2012) Sporotrichosis (Sporothrix schenckii infection) in the New South Wales mid-north coast, 2000–2010. Med J 196:588–590

    Google Scholar 

  • Song Y, Li SS, Zhong SX et al (2013) Report of 457 sporotrichosis cases from Jilin province, northeast China, a serious endemic region. J Eur Acad Dermatol Venereol 27:313–318

    Article  CAS  PubMed  Google Scholar 

  • Souza LL, Nascente PS, Nobre MO et al (2006) Isolation of Sporothrix schenckii from the nails of healthy cats. Braz J Microbiol 37:372–374

    Article  Google Scholar 

  • Staib F, Grosse G, Male O et al (1974) Utilization of creatinine and guanidino-acetic acid by Sporothrix schenckii. Microbiological epidemiological and pathologico-anatomical studies on the vector of sporotrichosis in Austria. Z Hautkr 49(14):607–613

    CAS  PubMed  Google Scholar 

  • Symmers WS (1968) Sporotrichosis in Ireland. Ulster Med J 37(2):85–101

    PubMed Central  CAS  PubMed  Google Scholar 

  • Takenaka M, Yoshizaki A, Utani A et al (2014) A survey of 165 sporotrichosis cases examined in Nagasaki prefecture from 1951 to 2012. Mycoses 57:294–298

    Article  PubMed  Google Scholar 

  • Travassos LR, Lloyd KO (1980) Sporothrix schenckii and related species of Ceratocystis. Microbiol Rev 44:683–721

    PubMed Central  CAS  PubMed  Google Scholar 

  • Vidal G, Rodríguez de Kop N (1993) Esporotricosis: enfoque epidemiológico, clínico y terapêutico/Sporotrichosis: clinical, therapeutic and epidemiologic overview. Arch Argent Dermatol 43(4):221–234

    Google Scholar 

  • Vismer HF, Hull PR (1997) Prevalence, epidemiology, and geographical distribution of Sporothrix schenckii infections in Gauteng, South Africa. Mycopathologia 137(3):137–143

    Google Scholar 

  • Wroblewska M, Swoboda-Kopec E, Kawecki D et al (2005) Infection by a dimorphic fungus Sporothrix schenckii in an immune compromised patient. Infection 33(4):289–291

    Article  CAS  PubMed  Google Scholar 

  • Zhang MF, Zhang YQ, Jiang P et al (1996) Isolation of Sporothrix schenckii from Reed. Chin J Dermatol 29:322–333

    Google Scholar 

  • Zhang YQ, Xu XG, Zhang M et al (2011) Sporotrichosis: clinical and histopathological manifestations. Am J Dermatopathol 33:296–302

    Article  PubMed  Google Scholar 

  • Zurita MS (2014) Esporotricosis y paracoccidioidomicosis en Perú: experiencias en prevención y control. Rev Peru Med Exp Salud Publica 31(2):352–357

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Iracilda Zeppone Carlos .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer International Publishing Switzerland

About this chapter

Cite this chapter

Carlos, I.Z., Batista-Duharte, A. (2015). Sporotrichosis: An Emergent Disease. In: Zeppone Carlos, I. (eds) Sporotrichosis. Springer, Cham. https://doi.org/10.1007/978-3-319-11912-0_1

Download citation

Publish with us

Policies and ethics