Abstract
Ensuring a well-functioning peritoneal dialysis (PD) catheter is of particular importance for the patient and healthcare providers. The main factors threating catheter function and its longevity are infections and mechanical catheter problems. The latter include obstruction, leakage, hernia, and malposition. Surgical expertise with the applied implantation method appears more important for preventing short- and long-term catheter complications than the catheter type, design, or implantation technique. In addition to catheter-related problems, membrane failure can be responsible for chronic PD (CPD) termination. The adverse metabolic effects of the PD fluids may exacerbate cardiovascular risk. Prevention, early recognition, and appropriate management of these complications are of crucial importance.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
McCormick BB, Bargman JM. Noninfectious complications of peritoneal dialysis: implications for patient and technique survival. J Am Soc Nephrol. 2007;18:3023–5.
Saha TC, Singh H. Noninfectious complications of peritoneal dialysis. South Med J. 2007;100:54–8.
Kim JE, Park SJ, Oh JY, Kim JH, Lee JS, Kim PK, Shin JI. Noninfectious complications of peritoneal dialysis in Korean children: a 26-year single-center study. Yonsei Med J. 2015;56:1359–64.
Bakkaloglu SA, Ekim M, Tumer N, Soylu K. The effect of CAPD on the lipid profile of pediatric patients. Perit Dial Int. 2000;20:568–71.
Verrina E, Edefonti A, Gianoglio B, Rinaldi S, Sorino P, Zacchello G, Lavoratti G, Maringhini S, Pecoraro C, Calevo MG, Turrini Dertenois L, Perfumo F. A multicenter experience on patient and technique survival in children on chronic dialysis. Pediatr Nephrol. 2004;19:82–90.
Honda M. The 1997 report of the Japanese National Registry data on pediatric peritoneal dialysis patients. Perit Dial Int. 1999;19(Suppl 2):S473–8.
Vidal E, Edefonti A, Murer L, Gianoglio B, Maringhini S, Pecoraro C, Sorino P, Leozappa G, Lavoratti G, Ratsch IM, Chimenz R, Verrina E, Italian Registry of Paediatric Chronic Dialysis. Peritoneal dialysis in infants: the experience of the Italian Registry of Paediatric Chronic Dialysis. Nephrol Dial Transplant. 2012;27:388–95.
Rinaldi S, Sera F, Verrina E, Edefonti A, Gianoglio B, Perfumo F, Sorino P, Zacchello G, Cutaia I, Lavoratti G, Leozappa G, Pecoraro C, Rizzoni G, Italian Registry of Pediatric Chronic Peritoneal Dialysis. Chronic peritoneal dialysis catheters in children: a fifteen-year experience of the Italian Registry of Pediatric Chronic Peritoneal Dialysis. Perit Dial Int. 2004;24:481–6.
Borzych-Duzalka D, Aki TF, Azocar M, White C, Harvey E, Mir S, Adragna M, Serdaroglu E, Sinha R, Samaille C, Vanegas JJ, Kari J, Barbosa L, Bagga A, Galanti M, Yavascan O, Leozappa G, Szczepanska M, Vondrak K, Tse KC, Schaefer F, Warady BA, International Pediatric Peritoneal Dialysis Network Registry. Peritoneal dialysis access revision in children: causes, interventions, and outcomes. Clin J Am Soc Nephrol. 2017;12:105–12.
Aksu N, Yavascan O, Anil M, Kara OD, Erdogan H, Bal A. A ten-year single-centre experience in children on chronic peritoneal dialysis – significance of percutaneous placement of peritoneal dialysis catheters. Nephrol Dial Transplant. 2007;22:2045–51.
Bakkaloglu SA, Ekim M, Sever L, Noyan A, Aksu N, Akman S, Elhan AH, Yalcinkaya F, Oner A, Kara OD, Caliskan S, Anarat A, Dusunsel R, Donmez O, Guven AG, Bakkaloglu A, Denizmen Y, Soylemezoglu O, Ozcelik G. Chronic peritoneal dialysis in Turkish children: a multicenter study. Pediatr Nephrol. 2005;20:644–51.
Radtke J, Lemke A, Kemper MJ, Nashan B, Koch M. Surgical complications after peritoneal dialysis catheter implantation depend on children’s weight. J Pediatr Surg. 2016;51:1317–20.
Carpenter JL, Fallon SC, Swartz SJ, Minifee PK, Cass DL, Nuchtern JG, Pimpalwar AP, Brandt ML. Outcomes after peritoneal dialysis catheter placement. J Pediatr Surg. 2016;51:730–3.
LaPlant MB, Saltzman DA, Segura BJ, Acton RD, Feltis BA, Hess DJ. Peritoneal dialysis catheter placement, outcomes and complications. Pediatr Surg Int. 2018;34:1239–44.
Radtke J, Schild R, Reismann M, Ridwelski RR, Kempf C, Nashan B, Rothe K, Koch M. Obstruction of peritoneal dialysis catheter is associated with catheter type and independent of omentectomy: a comparative data analysis from a transplant surgical and a pediatric surgical department. J Pediatr Surg. 2018;53:640–3.
Phan J, Stanford S, Zaritsky JJ, DeUgarte DA. Risk factors for morbidity and mortality in pediatric patients with peritoneal dialysis catheters. J Pediatr Surg. 2013;48:197–202.
Hagen SM, Lafranca JA, IJzermans JN, Dor FJ. A systematic review and meta-analysis of the influence of peritoneal dialysis catheter type on complication rate and catheter survival. Kidney Int. 2014;85:920–32.
Imani PD, Carpenter JL, Bell CS, Brandt ML, Braun MC, Swartz SJ. Peritoneal dialysis catheter outcomes in infants initiating peritoneal dialysis for end-stage renal disease. BMC Nephrol. 2018;19:231.
Ladd AP, Breckler FD, Novotny NM. Impact of primary omentectomy on longevity of peritoneal dialysis catheters in children. Am J Surg. 2011;201:401–4; discussion 404–405.
Nikibakhsh AA, Mahmoodzadeh H, Vali M, Enashaei A, Asem A, Yekta Z. Outcome of immediate use of the permanent peritoneal dialysis catheter in children with acute and chronic renal failure. Iran J Pediatr. 2013;23:171–6.
Zhang Q, Jiang C, Zhu W, Sun C, Xia Y, Tang T, Wan C, Shao Q, Liu J, Jin B, Zhang M. Peritoneal catheter fixation combined with straight upward tunnel and low implant position to prevent catheter malfunction. Nephrology (Carlton). 2018;23:247–52.
Stringel G, McBride W, Weiss R. Laparoscopic placement of peritoneal dialysis catheters in children. J Pediatr Surg. 2008;43:857–60.
Chen Y, Shao Y, Xu J. The survival and complication rates of laparoscopic versus open catheter placement in peritoneal dialysis patients: a meta-analysis. Surg Laparosc Endosc Percutan Tech. 2015;25:440–3.
Xie H, Zhang W, Cheng J, He Q. Laparoscopic versus open catheter placement in peritoneal dialysis patients: a systematic review and meta-analysis. BMC Nephrol. 2012;13:69.
Strippoli GF, Tong A, Johnson D, Schena FP, Craig JC. Catheter type, placement and insertion techniques for preventing peritonitis in peritoneal dialysis patients. Cochrane Database Syst Rev. 2004;(4):CD004680.
van Laanen JHH, Cornelis T, Mees BM, Litjens EJ, van Loon MM, Tordoir JHM, Peppelenbosch AG. Randomized controlled trial comparing open versus laparoscopic placement of a peritoneal dialysis catheter and outcomes: the CAPD I trial. Perit Dial Int. 2018;38:104–12.
Crabtree JH, Fishman A. A laparoscopic method for optimal peritoneal dialysis access. Am Surg. 2005;71:135–43.
Hu JC, Chiu KY, Wang SS, Chen CS, Ho HC, Yang CK, Chen CC, Wang SC, Lin CY, Hung SC, Cheng CL, Li JR. A modified application of peritoneal dialysis catheter implantation: a revolution from the laparoscope- to the nephroscope-assisted surgery. J Endourol. 2018;32:502–8.
Rahim KA, Seidel K, McDonald RA. Risk factors for catheter-related complications in pediatric peritoneal dialysis. Pediatr Nephrol. 2004;19:1021–8.
Donmez O, Durmaz O, Ediz B, Cigerdelen N, Kocak S. Catheter-related complications in children on chronic peritoneal dialysis. Adv Perit Dial. 2005;21:200–3.
Macchini F, Valade A, Ardissino G, Testa S, Edefonti A, Torricelli M, Luzzani S. Chronic peritoneal dialysis in children: catheter related complications. A single centre experience. Pediatr Surg Int. 2006;22:524–8.
Ozyer U, Harman A, Aytekin C, Boyvat F, Ozdemir N. Correction of displaced peritoneal dialysis catheters with an angular stiff rod. Acta Radiol. 2009;50:139–43.
Ratajczak A, Lange-Ratajczak M, Bobkiewicz A, Studniarek A. Surgical management of complications with peritoneal dialysis. Semin Dial. 2017;30:63–8.
Zorzanello MM, Fleming WJ, Prowant BE. Use of tissue plasminogen activator in peritoneal dialysis catheters: a literature review and one center’s experience. Nephrol Nurs J. 2004;31:534–7.
Krishnan RG, Moghal NE. Tissue plasminogen activator for blocked peritoneal dialysis catheters. Pediatr Nephrol. 2006;21:300.
Sakarcan A, Stallworth JR. Tissue plasminogen activator for occluded peritoneal dialysis catheter. Pediatr Nephrol. 2002;17:155–6.
Leblanc M, Ouimet D, Pichette V. Dialysate leaks in peritoneal dialysis. Semin Dial. 2001;14:50–4.
Hooman N, Esfahani ST, Mohkam M, Derakhshan A, Gheissari A, Vazirian S, Mortazavi F, Ghane-Sherbaff F, Falak-Aflaki B, Otoukesh H, Madani A, Sharifian-Dorcheh M, Mahdavi A, Esmaeile M, Naseri M, Azhir A, Merikhi A, Mohseni P, Ataei N, Fallahzadeh MH, Basiratnia M, Hosseini-Al-Hashemi G. The outcome of Iranian children on continuous ambulatory peritoneal dialysis: the first report of Iranian National Registry. Arch Iran Med. 2009;12:24–8.
Sojo ET, Grosman MD, Monteverde ML, Bailez MM, Delgado N. Fibrin glue is useful in preventing early dialysate leakage in children on chronic peritoneal dialysis. Perit Dial Int. 2004;24:186–90.
Aranda RA, Romao Junior JE, Kakehashi E, Domingos W, Sabbaga E, Marcondes M, Abensur H. Intraperitoneal pressure and hernias in children on peritoneal dialysis. Pediatr Nephrol. 2000;14:22–4.
Fischbach M, Warady BA. Peritoneal dialysis prescription in children: bedside principles for optimal practice. Pediatr Nephrol. 2009;24:1633–42; quiz 1640, 1642.
Jander A, Nowicki M, Tkaczyk M, Makulska I, Zwolinska D, Latoszynska J, Boguszewska-Baczkowska A, Grenda R, Balasz-Chmielewska I, Zagozdzon I, Zaluska-Lesniewska I, Zurowska A, Stefaniak E, Zachwieja J, Leszczynska B, Roszkowska-Blaim M, Zachwieja K, Pietrzyk JA, Wiercinski R, Zoch-Zwierz W, Stankiewicz R. Chronic peritoneal dialysis in infants – preliminary results of the multicenter survey. Przegl Lek. 2006;63(Suppl 3):72–4.
Tom CM, Dubina ED, Simms ER, de Virgilio C, Moazzez A. Outcomes of combined hernia repair and peritoneal dialysis catheter placement: a NSQIP analysis. Am Surg. 2018;84:1604–7.
Bargman JM. Complications of peritoneal dialysis related to increased intraabdominal pressure. Kidney Int Suppl. 1993;40:S75–80.
Schmitt CP, Zaloszyc A, Schaefer B, Fischbach M. Peritoneal dialysis tailored to pediatric needs. Int J Nephrol. 2011;2011:940267.
Bakkaloglu SA, Ekim M, Tumer N, Gungor A, Yilmaz S. Pleurodesis treatment with tetracycline in peritoneal dialysis-complicated hydrothorax. Pediatr Nephrol. 1999;13:637–8.
Borzych D, Ley S, Schaefer F, Billing H, Ley-Zaporozhan J, Schenk J, Schmitt CP. Dialysate leakage into pericardium in an infant on long-term peritoneal dialysis. Pediatr Nephrol. 2008;23:335–8.
Camilleri B, Glancey G, Pledger D, Williams P. The icodextrin black line sign to confirm a pleural leak in a patient on peritoneal dialysis. Perit Dial Int. 2004;24:197.
Szeto CC, Chow KM. Pathogenesis and management of hydrothorax complicating peritoneal dialysis. Curr Opin Pulm Med. 2004;10:315–9.
Kim YL. Update on mechanisms of ultrafiltration failure. Perit Dial Int. 2009;29(Suppl 2):S123–7.
Raby AC, Gonzalez-Mateo GT, Williams A, Topley N, Fraser D, Lopez-Cabrera M, Labeta MO. Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosis. Kidney Int. 2018;94:346–62.
Chung SH, Heimburger O, Lindholm B. Poor outcomes for fast transporters on PD: the rise and fall of a clinical concern. Semin Dial. 2008;21:7–10.
Saxena R. Pathogenesis and treatment of peritoneal membrane failure. Pediatr Nephrol. 2008;23:695–703.
Schaefer F, Klaus G, Mehls O. Peritoneal transport properties and dialysis dose affect growth and nutritional status in children on chronic peritoneal dialysis. Mid-European Pediatric Peritoneal Dialysis Study Group. J Am Soc Nephrol. 1999;10:1786–92.
Canepa A, Verrina E, Perfumo F. Use of new peritoneal dialysis solutions in children. Kidney Int Suppl. 2008;(108):S137–44.
Michallat AC, Dheu C, Loichot C, Danner S, Fischbach M. Long daytime exchange in children on continuous cycling peritoneal dialysis: preservation of drained volume because of icodextrin use. Adv Perit Dial. 2005;21:195–9.
Htay H, Johnson DW, Wiggins KJ, Badve SV, Craig JC, Strippoli GF, Cho Y. Biocompatible dialysis fluids for peritoneal dialysis. Cochrane Database Syst Rev. 2018;10:CD007554.
Honda M, Warady BA. Long-term peritoneal dialysis and encapsulating peritoneal sclerosis in children. Pediatr Nephrol. 2010;25:75–81.
Stefanidis CJ, Shroff R. Encapsulating peritoneal sclerosis in children. Pediatr Nephrol. 2014;29:2093–103.
Brown EA, Bargman J, van Biesen W, Chang MY, Finkelstein FO, Hurst H, Johnson DW, Kawanishi H, Lambie M, de Moraes TP, Morelle J, Woodrow G. Length of time on peritoneal dialysis and encapsulating peritoneal sclerosis – position paper for ISPD: 2017 update. Perit Dial Int. 2017;37:362–74.
Vidal E, Edefonti A, Puteo F, Chimenz R, Gianoglio B, Lavoratti G, Leozappa G, Maringhini S, Mencarelli F, Pecoraro C, Ratsch IM, Cannavo R, De Palo T, Testa S, Murer L, Verrina E, Italian Registry of Pediatric Chronic Dialysis. Encapsulating peritoneal sclerosis in paediatric peritoneal dialysis patients: the experience of the Italian Registry of Pediatric Chronic Dialysis. Nephrol Dial Transplant. 2013;28:1603–9.
Hoshii S, Honda M. High incidence of encapsulating peritoneal sclerosis in pediatric patients on peritoneal dialysis longer than 10 years. Perit Dial Int. 2002;22:730–1.
Shroff R, Stefanidis CJ, Askiti V, Edefonti A, Testa S, Ekim M, Kavaz A, Ariceta G, Bakkaloglu S, Fischbach M, Klaus G, Zurowska A, Holtta T, Jankauskiene A, Vondrak K, Vande Walle J, Schmitt CP, Watson AR, European Paediatric Dialysis Working Group. Encapsulating peritoneal sclerosis in children on chronic PD: a survey from the European Paediatric Dialysis Working Group. Nephrol Dial Transplant. 2013;28:1908–14.
Ekim M, Fitoz S, Yagmurlu A, Ensari A, Yuksel S, Acar B, Ozcakar ZB, Kendirli T, Bingoler B, Yalcinkaya F. Encapsulating peritoneal sclerosis in paediatric peritoneal dialysis patients. Nephrology (Carlton). 2005;10:341–3.
Kawaguchi Y, Saito A, Kawanishi H, Nakayama M, Miyazaki M, Nakamoto H, Tranaeus A. Recommendations on the management of encapsulating peritoneal sclerosis in Japan, 2005: diagnosis, predictive markers, treatment, and preventive measures. Perit Dial Int. 2005;25(Suppl 4):S83–95.
Bakkaloglu SA, Saygili A, Sever L, Noyan A, Akman S, Ekim M, Aksu N, Doganay B, Yildiz N, Duzova A, Soylu A, Alpay H, Sonmez F, Civilibal M, Erdem S, Kardelen F. Assessment of cardiovascular risk in paediatric peritoneal dialysis patients: a Turkish Pediatric Peritoneal Dialysis Study Group (TUPEPD) report. Nephrol Dial Transplant. 2009;24:3525–32.
Bonthuis M, van Stralen KJ, Jager KJ, Baiko S, Jahnukainen T, Laube GF, Podracka L, Seeman T, Tyerman K, Ulinski T, Groothoff JW, Schaefer F, Verrina E. Dyslipidaemia in children on renal replacement therapy. Nephrol Dial Transplant. 2014;29:594–603.
Buyan N, Bideci A, Ozkaya O, Ortac E, Bakkaloglu S, Gonen S, Peru H, Soylemezoglu O, Cinaz P. Leptin and resistin levels and their relationships with glucose metabolism in children with chronic renal insufficiency and undergoing dialysis. Nephrology (Carlton). 2006;11:192–6.
Canpolat N, Caliskan S, Sever L, Guzeltas A, Kantarci F, Candan C, Civilibal M, Kasapcopur O, Arisoy N. Glucose intolerance: is it a risk factor for cardiovascular disease in children with chronic kidney disease? Pediatr Nephrol. 2012;27:627–35.
KDIGO. KDIGO clinical practice guideline for lipid management in chronic kidney disease. Kidney Int Suppl. 2013;3(3):259.
Kavey RE, Allada V, Daniels SR, Hayman LL, McCrindle BW, Newburger JW, Parekh RS, Steinberger J, American Heart Association Expert Panel on Population and Prevention Science; the Councils on Cardiovascular Disease in the Young, Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; and the Interdisciplinary Working Group on Quality of Care and Outcomes Research. Cardiovascular risk reduction in high-risk pediatric patients: a scientific statement from the American Heart Association Expert Panel on Population and Prevention Science; the Councils on Cardiovascular Disease in the Young, Epidemiology and Prevention, Nutrition, Physical Activity and Metabolism, High Blood Pressure Research, Cardiovascular Nursing, and the Kidney in Heart Disease; and the Interdisciplinary Working Group on Quality of Care and Outcomes Research. J Cardiovasc Nurs. 2007;22:218–53.
Factor KF. Potassium management in pediatric peritoneal dialysis patients: can a diet with increased potassium maintain a normal serum potassium without a potassium supplement? Adv Perit Dial. 2007;23:167–9.
Khan AN, Bernardini J, Johnston JR, Piraino B. Hypokalemia in peritoneal dialysis patients. Perit Dial Int. 1996;16:652.
Hutchinson AJ. Serum magnesium and end-stage renal disease. Perit Dial Int. 1997;17:327–9.
Wei M, Esbaei K, Bargman JM, Oreopoulos DG. Inverse correlation between serum magnesium and parathyroid hormone in peritoneal dialysis patients: a contributing factor to adynamic bone disease? Int Urol Nephrol. 2006;38:317–22.
Greenberg A, Bernardini J, Piraino BM, Johnston JR, Perlmutter JA. Hemoperitoneum complicating chronic peritoneal dialysis: single-center experience and literature review. Am J Kidney Dis. 1992;19:252–6.
Vidal E, Alberici I, Verrina E, Italian Registry of Pediatric Chronic Dialysis. Acute pancreatitis in children on chronic maintenance dialysis. Pediatr Nephrol. 2019;34(9):1501–12.
Bastani B, Mifflin TE, Lovell MA, Westervelt FB, Bruns DE. Serum amylases in chronic and end-stage renal failure: effects of mode of therapy, race, diabetes and peritonitis. Am J Nephrol. 1987;7:292–9.
Wang R, Leesch V, Turner P, Moberly JB, Martis L. Kinetic analysis of icodextrin interference with serum amylase assays. Adv Perit Dial. 2002;18:96–9.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2021 Springer Nature Switzerland AG
About this chapter
Cite this chapter
Bakkaloğlu, S.A., Sethna, C.B. (2021). Noninfectious Complications of Peritoneal Dialysis in Children. In: Warady, B.A., Alexander, S.R., Schaefer, F. (eds) Pediatric Dialysis. Springer, Cham. https://doi.org/10.1007/978-3-030-66861-7_17
Download citation
DOI: https://doi.org/10.1007/978-3-030-66861-7_17
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-030-66860-0
Online ISBN: 978-3-030-66861-7
eBook Packages: MedicineMedicine (R0)