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Non-Thrombotic Vascular Diseases of the Chest

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Clinically Oriented Pulmonary Imaging

Part of the book series: Respiratory Medicine ((RM))

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Abstract

Non-thrombotic pulmonary vascular diseases may involve any portion of the pulmonary vascular tree from the main pulmonary artery through to the capillaries, venules, and central veins. They may be congenital or acquired. In this chapter, the typical presentation, important laboratory, as well as imaging findings of the more common or clinically significant entities are reviewed.

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References

  1. Siripornpitak S, Reddy GP, Schwitter J, Higgins CB. Pulmonary artery sling: anatomical and functional evaluation by MRI. J Comput Assist Tomogr. 1997;21(5):766–8.

    Article  PubMed  CAS  Google Scholar 

  2. Lee KH, Yoon CS, Choe KO, et al. Use of imaging for assessing anatomical relationships of tracheobronchial anomalies associated with left pulmonary artery sling. Pediatr Radiol. 2001;31(4):269–78.

    Article  PubMed  CAS  Google Scholar 

  3. Newman B. Congenital bronchopulmonary foregut malformations: concepts and controversies. Pediatr Radiol. 2006;36(8):773–91.

    Article  PubMed  Google Scholar 

  4. Zylak CJ, Eyler WR, Spizarny DL, Stone CH. Developmental lung anomalies in the adult: radiologic-pathologic correlation. Radiographics. 2002;22 Spec No:S25–43.

    Google Scholar 

  5. Rosenberg BF, Tantiwongse T, Wittenborg MH. Anomalous course of left pulmonary artery with respiratory obstruction. Radiology. 1956;67(3):339–45.

    PubMed  CAS  Google Scholar 

  6. Newman B, Meza MP, Towbin RB, Nido PD. Left pulmonary artery sling: diagnosis and delineation of associated tracheobronchial anomalies with MR. Pediatr Radiol. 1996;26(9):661–8.

    Article  PubMed  CAS  Google Scholar 

  7. Berdon WE, Baker DH, Wung JT, et al. Complete cartilage-ring tracheal stenosis associated with anomalous left pulmonary artery: the ring-sling complex. Radiology. 1984;152(1):57–64.

    PubMed  CAS  Google Scholar 

  8. Chen SJ, Lee WJ, Lin MT, et al. Left pulmonary artery sling complex: computed tomography and hypothesis of embryogenesis. Ann Thorac Surg. 2007;84(5):1645–50.

    Article  PubMed  Google Scholar 

  9. Newman B, Gondor M. MR evaluation of right pulmonary agenesis and vascular airway compression in pediatric patients. Am J Roentgenol. 1997;168(1):55–8.

    CAS  Google Scholar 

  10. Collins RT II, Weinberg PM, Ewing S, Fogel M. Images in cardiovascular medicine: pulmonary artery sling in an asymptomatic 15-year-old boy. Circulation. 2008;117(18):2403–6.

    Article  PubMed  Google Scholar 

  11. Ganesh V, Hoey ET, Gopalan D. Pulmonary artery sling: an unexpected finding on cardiac multidetector CT. Postgrad Med J. 2009;85(1001):128.

    Article  PubMed  CAS  Google Scholar 

  12. Kagadis GC, Panagiotopoulou EC, Priftis KN, Vaos G, Nikiforidis GC, Anthracopoulos MB. Preoperative evaluation of the trachea in a child with pulmonary artery sling using 3-dimensional computed tomographic imaging and virtual bronchoscopy. J Pediatr Surg. 2007;42(5):E9–13.

    Article  PubMed  Google Scholar 

  13. du Plessis AM, Andronikou S, Goussaard P. Bridging bronchus and sling left pulmonary artery: a rare entity demonstrated by coronal CT with 3D rendering display and minimal-intensity projections. Pediatr Radiol. 2008;38(9):1024–6.

    Article  PubMed  Google Scholar 

  14. Baden W, Schaefer J, Kumpf M, et al. Comparison of imaging techniques in the diagnosis of bridging bronchus. Eur Respir. 2008;31(5):1125–31.

    Article  CAS  Google Scholar 

  15. Kieffer SA, Amplatz K, Anderson RC, Lillehei CW. Proximal interruption of a pulmonary artery. Am J Roentgenol Radium Ther Nucl Med. 1965;95(3):592–7.

    PubMed  CAS  Google Scholar 

  16. Bouros D, Pare P, Panagou P, Tsintiris K, Siafakas N. The varied manifestation of pulmonary artery agenesis in adulthood. Chest. 1995;108(3):670–6.

    Article  PubMed  CAS  Google Scholar 

  17. Rene M, Sans J, Dominguez J, Sancho C, Valldeperas J. Unilateral pulmonary artery agenesis presenting with hemoptysis: treatment by embolization of systemic collaterals. Cardiovasc Intervent Radiol. 1995;18(4):251–4.

    Article  PubMed  CAS  Google Scholar 

  18. Jaskolka J, Wu L, Chan RP, Faughnan ME. Imaging of hereditary hemorrhagic telangiectasia. Am J Roentgenol. 2004;183(2):307–14.

    Google Scholar 

  19. Abdel Aal AK, Hamed MF, Biosca RF, Saddekni S, Raghuram K. Occlusion time for Amplatzer vascular plug in the management of pulmonary arteriovenous malformations. Am J Roentgenol. 2009;192(3):793–9.

    Article  Google Scholar 

  20. Gupta P, Mordin C, Curtis J, Hughes JM, Shovlin CL, Jackson JE. Pulmonary arteriovenous malformations: effect of embolization on right-to-left shunt, hypoxemia, and exercise tolerance in 66 patients. Am J Roentgenol. 2002;179(2):347–55.

    CAS  Google Scholar 

  21. Brown KK. Pulmonary vasculitis. Proc Am Thorac Soc. 2006;3(1):48–57.

    Article  PubMed  CAS  Google Scholar 

  22. Hansell DM. Small-vessel diseases of the lung: CT-pathologic correlates. Radiology. 2002;225(3):639–53.

    Article  PubMed  Google Scholar 

  23. Travis WD, Colby TV, Lombard C, Carpenter HA. A clinicopathologic study of 34 cases of diffuse pulmonary hemorrhage with lung biopsy confirmation. Am J Surg Pathol. 1990;14(12):1112–25.

    Article  PubMed  CAS  Google Scholar 

  24. Watts RA, Lane SE, Bentham G, Scott DG. Epidemiology of systemic vasculitis: a ten-year study in the United Kingdom. Arthritis Rheum. 2000;43(2):414–9.

    Article  PubMed  CAS  Google Scholar 

  25. Hagen EC, Daha MR, Hermans J, et al. Diagnostic value of standardized assays for anti-neutrophil cytoplasmic antibodies in idiopathic systemic vasculitis: EC/BCR project for ANCA assay standardization. Kidney Int. 1998;53(3):743–53.

    Article  PubMed  CAS  Google Scholar 

  26. Frankel SK, Cosgrove GP, Fischer A, Meehan RT, Brown KK. Update in the diagnosis and management of pulmonary vasculitis. Chest. 2006;129(2):452–65.

    Article  PubMed  Google Scholar 

  27. Chung MP, Yi CA, Lee HY, Han J, Lee KS. Imaging of pulmonary vasculitis. Radiology. 2010;255(2):322–41.

    Article  PubMed  Google Scholar 

  28. Jennette JC, Falk RJ, Andrassy K, et al. Nomenclature of systemic vasculitides: proposal of an international consensus conference. Arthritis Rheum. 1994;37(2):187–92.

    Article  PubMed  CAS  Google Scholar 

  29. Guillevin L, Durand-Gasselin B, Cevallos R, et al. Microscopic polyangiitis: clinical and laboratory findings in eighty-five patients. Arthritis Rheum. 1999;42(3):421–30.

    Article  PubMed  CAS  Google Scholar 

  30. Mulder AH, Horst G, van Leeuwen MA, Limburg PC, Kallenberg CG. Antineutrophil cytoplasmic antibodies in rheumatoid arthritis: characterization and clinical correlations. Arthritis Rheum. 1993;36(8):1054–60.

    Article  PubMed  CAS  Google Scholar 

  31. Schnabel A, Csernok E, Isenberg DA, Mrowka C, Gross WL. Antineutrophil cytoplasmic antibodies in systemic lupus erythematosus: prevalence, specificities, and clinical significance. Arthritis Rheum. 1995;38(5):633–7.

    Article  PubMed  CAS  Google Scholar 

  32. Cojocaru M, Cojocaru IM, Iacob SA. Prevalence of anti-neutrophil cytoplasmic antibodies in patients with chronic hepatitis C infection associated mixed cryoglobulinemia. Rom J Intern Med. 2006;44(4):427–31.

    PubMed  CAS  Google Scholar 

  33. Zholudev A, Zurakowski D, Young W, Leichtner A, Bousvaros A. Serologic testing with ANCA, ASCA, and anti-OmpC in children and young adults with Crohn’s disease and ulcerative colitis: diagnostic value and correlation with disease phenotype. Am J Gastroenterol. 2004;99(11):2235–41.

    Article  PubMed  Google Scholar 

  34. Erkan F, Gul A, Tasali E. Pulmonary manifestations of Behcet’s disease. Thorax. 2001;56(7):572–8.

    Article  PubMed  CAS  Google Scholar 

  35. Hiller N, Lieberman S, Chajek-Shaul T, Bar-Ziv J, Shaham D. Thoracic manifestations of Behcet disease at CT. Radiographics. 2004;24(3):801–8.

    Article  PubMed  Google Scholar 

  36. Hamuryudan V, Yurdakul S, Moral F, et al. Pulmonary arterial aneurysms in Behcet’s syndrome: a report of 24 cases. Br J Rheumatol. 1994;33(1):48–51.

    Article  PubMed  CAS  Google Scholar 

  37. Uzun O, Akpolat T, Erkan L. Pulmonary vasculitis in Behcet disease: a cumulative analysis. Chest. 2005;127(6):2243–53.

    Article  PubMed  Google Scholar 

  38. Chae EJ, Do KH, Seo JB, et al. Radiologic and clinical findings of Behcet disease: comprehensive review of multisystemic involvement. Radiographics. 2008;28(5):e31.

    Article  PubMed  Google Scholar 

  39. Tunaci M, Ozkorkmaz B, Tunaci A, Gul A, Engin G, Acunas B. CT findings of pulmonary artery aneurysms during treatment for Behcet’s disease. Am J Roentgenol. 1999;172(3):729–33.

    CAS  Google Scholar 

  40. Marten K, Schnyder P, Schirg E, Prokop M, Rummeny EJ, Engelke C. Pattern-based differential diagnosis in pulmonary vasculitis using volumetric CT. Am J Roentgenol. 2005;184(3):720–33.

    Google Scholar 

  41. Seko Y. Giant cell and Takayasu arteritis. Curr Opin Rheumatol. 2007;19(1):39–43.

    Article  PubMed  Google Scholar 

  42. Gotway MB, Araoz PA, Macedo TA, et al. Imaging findings in Takayasu’s arteritis. Am J Roentgenol. 2005;184(6):1945–50.

    Google Scholar 

  43. Choe YH, Han BK, Koh EM, Kim DK, Do YS, Lee WR. Takayasu’s arteritis: assessment of disease activity with contrast-enhanced MR imaging. Am J Roentgenol. 2000;175(2):505–11.

    CAS  Google Scholar 

  44. Schmidt WA, Blockmans D. Use of ultrasonography and positron emission tomography in the diagnosis and assessment of large-vessel vasculitis. Curr Opin Rheumatol. 2005;17(1):9–15.

    Article  PubMed  Google Scholar 

  45. Lee KS, Kim TS, Fujimoto K, et al. Thoracic manifestation of Wegener’s granulomatosis: CT findings in 30 patients. Eur Radiol. 2003;13(1):43–51.

    Article  PubMed  Google Scholar 

  46. Komocsi A, Reuter M, Heller M, Murakozi H, Gross WL, Schnabel A. Active disease and residual damage in treated Wegener’s granulomatosis: an observational study using pulmonary high-resolution computed tomography. Eur Radiol. 2003;13(1):36–42.

    PubMed  Google Scholar 

  47. Lohrmann C, Uhl M, Kotter E, Burger D, Ghanem N, Langer M. Pulmonary manifestations of Wegener granulomatosis: CT findings in 57 patients and a review of the literature. Eur J Radiol. 2005;53(3):471–7.

    Article  PubMed  Google Scholar 

  48. Ananthakrishnan L, Sharma N, Kanne JP. Wegener’s granulomatosis in the chest: high-resolution CT findings. Am J Roentgenol. 2009;192(3):676–82.

    Article  Google Scholar 

  49. Franks TJ, Koss MN. Pulmonary capillaritis. Curr Opin Pulm Med. 2000;6(5):430–5.

    Article  PubMed  CAS  Google Scholar 

  50. Mayberry JP, Primack SL, Muller NL. Thoracic manifestations of systemic autoimmune diseases: radiographic and high-resolution CT findings. Radiographics. 2000;20(6):1623–35.

    PubMed  CAS  Google Scholar 

  51. Castaner E, Alguersuari A, Gallardo X, et al. When to suspect pulmonary vasculitis: radiologic and clinical clues. Radiographics. 2010;30(1):33–53.

    Article  PubMed  Google Scholar 

  52. Bosch X, Guilabert A, Espinosa G, Mirapeix E. Treatment of antineutrophil cytoplasmic antibody associated vasculitis: a systematic review. JAMA. 2007;298(6):655–69.

    Article  PubMed  CAS  Google Scholar 

  53. Keogh KA, Specks U. Churg–Strauss syndrome. Semin Respir Crit Care Med. 2006;27(2):148–57.

    Article  PubMed  Google Scholar 

  54. Choi YH, Im JG, Han BK, Kim JH, Lee KY, Myoung NH. Thoracic manifestation of Churg–Strauss syndrome: radiologic and clinical findings. Chest. 2000;117(1):117–24.

    Article  PubMed  CAS  Google Scholar 

  55. Keogh KA, Specks U. Churg–Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists. Am J Med. 2003;115(4):284–90.

    Article  PubMed  CAS  Google Scholar 

  56. Solans R, Bosch JA, Perez-Bocanegra C, et al. Churg–Strauss syndrome: outcome and long-term follow-up of 32 patients. Rheumatology. 2001;40(7):763–71.

    Article  PubMed  CAS  Google Scholar 

  57. Silva CI, Muller NL. Churg–Strauss syndrome: imaging of the chest. Philladelphia: Saunders-Elsevier; 2008. p. 821–7.

    Google Scholar 

  58. Katzenstein AL. Diagnostic features and differential diagnosis of Churg–Strauss syndrome in the lung: a review. Am J Clin Pathol. 2000;114(5):767–72.

    Article  PubMed  CAS  Google Scholar 

  59. Silva CI, Muller NL, Fujimoto K, Johkoh T, Ajzen SA, Churg A. Churg–Strauss syndrome: high resolution CT and pathologic findings. J Thorac Imaging. 2005;20(2):74–80.

    Article  PubMed  Google Scholar 

  60. Johkoh T, Muller NL, Akira M, et al. Eosinophilic lung diseases: diagnostic accuracy of thin-section CT in 111 patients. Radiology. 2000;216(3):773–80.

    PubMed  CAS  Google Scholar 

  61. Kim YK, Lee KS, Chung MP, et al. Pulmonary involvement in Churg–Strauss syndrome: an analysis of CT, clinical, and pathologic findings. Eur Radiol. 2007;17(12):3157–65.

    Article  PubMed  Google Scholar 

  62. Ioachimescu OC, Sieber S, Kotch A. Idiopathic pulmonary haemosiderosis revisited. Eur Respir. 2004;24(1):162–70.

    Article  CAS  Google Scholar 

  63. Green RJ, Ruoss SJ, Kraft SA, Duncan SR, Berry GJ, Raffin TA. Pulmonary capillaritis and alveolar hemorrhage: update on diagnosis and management. Chest. 1996;110(5):1305–16.

    Article  PubMed  CAS  Google Scholar 

  64. Niles JL, Bottinger EP, Saurina GR, et al. The syndrome of lung hemorrhage and nephritis is usually an ANCA-associated condition. Arch Intern Med. 1996;156(4):440–5.

    Article  PubMed  CAS  Google Scholar 

  65. Jennette JC, Falk RJ. Small-vessel vasculitis. N Engl J Med. 1997;337(21):1512–23.

    Article  PubMed  CAS  Google Scholar 

  66. Akikusa B, Sato T, Ogawa M, Ueda S, Kondo Y. Necrotizing alveolar capillaritis in autopsy cases of microscopic polyangiitis: incidence, histopathogenesis, and relationship with systemic vasculitis. Arch Pathol Lab Med. 1997;121(2):144–9.

    PubMed  CAS  Google Scholar 

  67. Kim JS, Lee KS, Koh EM, Kim SY, Chung MP, Han J. Thoracic involvement of systemic lupus erythematosus: clinical, pathologic, and radiologic findings. J Comput Assist Tomogr. 2000;24(1):9–18.

    Article  PubMed  CAS  Google Scholar 

  68. Kim EA, Lee KS, Johkoh T, et al. Interstitial lung diseases associated with collagen vascular diseases: radiologic and histopathologic findings. Radiographics. 2002;22 Spec No:S151–65.

    PubMed  Google Scholar 

  69. Primack SL, Miller RR, Muller NL. Diffuse pulmonary hemorrhage: clinical, pathologic, and imaging features. Am J Roentgenol. 1995;164(2):295–300.

    CAS  Google Scholar 

  70. Lauque D, Cadranel J, Lazor R, et al. Microscopic polyangiitis with alveolar hemorrhage: a study of 29 cases and review of the literature: Groupe d’Etudes et de Recherche sur les Maladies “Orphelines” Pulmonaires (GERM“O”P). Medicine (Baltimore). 2000;79(4):222–33.

    Article  CAS  Google Scholar 

  71. Cheah FK, Sheppard MN, Hansell DM. Computed tomography of diffuse pulmonary haemorrhage with pathological correlation. Clin Radiol. 1993;48(2):89–93.

    Article  PubMed  CAS  Google Scholar 

  72. Eschun GM, Mink SN, Sharma S. Pulmonary interstitial fibrosis as a presenting manifestation in perinuclear antineutrophilic cytoplasmic antibody microscopic polyangiitis. Chest. 2003;123(1):297–301.

    Article  PubMed  Google Scholar 

  73. Nguyen ET, Silva CI, Seely JM, Chong S, Lee KS, Muller NL. Pulmonary artery aneurysms and pseudoaneurysms in adults: findings at CT and radiography. Am J Roentgenol. 2007;188(2):W126–34.

    Article  Google Scholar 

  74. DeLima LG, Wynands JE, Bourke ME, Walley VM. Catheter-induced pulmonary artery false aneurysm and rupture: case report and review. J Cardiothorac Vasc Anesth. 1994;8(1):70–5.

    Article  PubMed  CAS  Google Scholar 

  75. Fraser RS, Muller NL, Colman N, Pare PD. Pulmonary hypertension and edema. In: Muller NL, Colman N, Pare PD, editors. Diagnosis of diseases of the chest. Philladelpia: Saunders; 1999. p. 1935–7.

    Google Scholar 

  76. Loyd JE, Tillman BF, Atkinson JB, Des Prez RM. Mediastinal fibrosis complicating histoplasmosis. Medicine (Baltimore). 1988;67(5):295–310.

    CAS  Google Scholar 

  77. Lloyd JE, Tillman BF, Atkinson JB, Des Prez RM. Mediastinal fibrosis complicating histoplasmosis. Medicine (Baltimore). 1988;67:295–310.

    Google Scholar 

  78. Goodwin RA, Nickell JA, Des Prez RM. Mediastinal fibrosis complicating healed primary histoplasmosis and tuberculosis. Medicine (Baltimore). 1972;51(3):227–46.

    Article  CAS  Google Scholar 

  79. Peebles RS, Carpenter CT, Dupont WD, Loyd JE. Mediastinal fibrosis is associated with human leukocyte antigen-A2. Chest. 2000;117(2):482–5.

    Article  PubMed  CAS  Google Scholar 

  80. Rossi SE, McAdams HP, Rosado-de-Christenson ML, Franks TJ, Galvin JR. Fibrosing mediastinitis. Radiographics. 2001;21(3):737–57.

    PubMed  CAS  Google Scholar 

  81. Mole TM, Glover J, Sheppard MN. Sclerosing mediastinitis: a report on 18 cases. Thorax. 1995;50(3):280–3.

    Article  PubMed  CAS  Google Scholar 

  82. Hanley PC, Shub C, Lie JT. Constrictive pericarditis associated with combined idiopathic retroperitoneal and mediastinal fibrosis. Mayo Clin Proc. 1984;59(5):300–4.

    Google Scholar 

  83. Kalweit G, Huwer H, Straub U, Gams E. Mediastinal compression syndromes due to idiopathic fibrosing mediastinitis—report of three cases and review of the literature. Thorac Cardiovasc Surg. 1996;44(2):105–9.

    Article  PubMed  CAS  Google Scholar 

  84. Cochrane A, Warren R, Mullerworth M, Manolas E. Fibrosing mediastinitis with coronary artery involvement. Ann Thorac Surg. 1991;51(4):652–4.

    Article  PubMed  CAS  Google Scholar 

  85. Flieder DB, Suster S, Moran CA. Idiopathic fibroinflammatory (fibrosing/sclerosing) lesions of the mediastinum: a study of 30 cases with emphasis on morphologic heterogeneity. Mod Pathol. 1999;12(3):257–64.

    Google Scholar 

  86. Mathisen DJ, Grillo HC. Clinical manifestation of mediastinal fibrosis and histoplasmosis. Ann Thorac Surg. 1992;54(6):1053–57; discussion 1057–58.

    Google Scholar 

  87. Urschel HC Jr, Razzuk MA, Netto GJ, Disiere J, Chung SY. Sclerosing mediastinitis: improved management with histoplasmosis titer and ketoconazole. Ann Thorac Surg. 1990;50(2):215–21.

    Article  PubMed  Google Scholar 

  88. Sherrick AD, Brown LR, Harms GF, Myers JL. The radiographic findings of fibrosing mediastinitis. Chest. 1994;106(2):484–9.

    Article  PubMed  CAS  Google Scholar 

  89. Farmer DW, Moore E, Amparo E, Webb WR, Gamsu G, Higgins CB. Calcific fibrosing mediastinitis: demonstration of pulmonary vascular obstruction by magnetic resonance imaging. Am J Roentgenol. 1984;143(6):1189–91.

    CAS  Google Scholar 

  90. Rodriguez E, Soler R, Pombo F, Requejo I, Montero C. Fibrosing mediastinitis: CT and MR findings. Clin Radiol. 1998;53(12):907–10.

    Article  PubMed  CAS  Google Scholar 

  91. Weinstein JB, Aronberg DJ, Sagel SS. CT of fibrosing mediastinitis: findings and their utility. Am J Roentgenol. 1983;141(2):247–51.

    CAS  Google Scholar 

  92. Chan CK, Hutcheon MA, Hyland RH, Smith GJ, Patterson BJ, Matthay RA. Pulmonary tumor embolism: a critical review of clinical, imaging, and hemodynamic features. J Thorac Imaging. 1987;2(4):4–14.

    Article  PubMed  CAS  Google Scholar 

  93. Kane RD, Hawkins HK, Miller JA, Noce PS. Microscopic pulmonary tumor emboli associated with dyspnea. Cancer. 1975;36(4):1473–82.

    Article  PubMed  CAS  Google Scholar 

  94. Roberts KE, Hamele-Bena D, Saqi A, Stein CA, Cole RP. Pulmonary tumor embolism: a review of the literature. Am J Med. 2003;115(3):228–32.

    Article  PubMed  Google Scholar 

  95. Rossi SE, Goodman PC, Franquet T. Nonthrombotic pulmonary emboli. Am J Roentgenol. 2000;174(6):1499–508.

    CAS  Google Scholar 

  96. Jakel J, Ramaswamy A, Kohler U, Barth PJ. Massive pulmonary tumor microembolism from a hepatocellular carcinoma. Pathol Res Pract. 2006;202(5):395–9.

    Article  PubMed  Google Scholar 

  97. Brock SJ, Fuller C, Iveson TJ. Pulmonary tumour emboli: a difficult ante-mortem diagnosis. Clin Oncol. 2000;12(1):56–7.

    CAS  Google Scholar 

  98. Shepard JA, Moore EH, Templeton PA, McLoud TC. Pulmonary intravascular tumor emboli: dilated and beaded peripheral pulmonary arteries at CT. Radiology. 1993;187(3):797–801.

    PubMed  CAS  Google Scholar 

  99. Tack D, Nollevaux MC, Gevenois PA. Tree-in-bud pattern in neoplastic pulmonary emboli. Am J Roentgenol. 2001;176(6):1421–2.

    CAS  Google Scholar 

  100. Fred HL, Harle TS. Septic pulmonary embolism. Am Fam Phys/GP. 1970;1(5):81–7.

    CAS  Google Scholar 

  101. Roberts WC, Buchbinder NA. Right-sided valvular infective endocarditis: a clinicopathologic study of twelve necropsy patients. Am J Med. 1972;53(1):7–19.

    Article  PubMed  CAS  Google Scholar 

  102. Huang RM, Naidich DP, Lubat E, Schinella R, Garay SM, McCauley DI. Septic pulmonary emboli: CT-radiographic correlation. Am J Roentgenol. 1989;153(1):41–5.

    CAS  Google Scholar 

  103. Cook RJ, Ashton RW, Aughenbaugh GL, Ryu JH. Septic pulmonary embolism: presenting features and clinical course of 14 patients. Chest. 2005;128(1):162–6.

    Article  PubMed  Google Scholar 

  104. MacMillan JC, Milstein SH, Samson PC. Clinical spectrum of septic pulmonary embolism and infarction. J Thorac Cardiovasc Surg. 1978;75(5):670–9.

    PubMed  CAS  Google Scholar 

  105. Kuhlman JE, Fishman EK, Teigen C. Pulmonary septic emboli: diagnosis with CT. Radiology. 1990;174(1):211–3.

    PubMed  CAS  Google Scholar 

  106. Kuhlman JE, Fishman EK, Siegelman SS. Invasive pulmonary aspergillosis in acute leukemia: characteristic findings on CT, the CT halo sign, and the role of CT in early diagnosis. Radiology. 1985;157(3):611–4.

    PubMed  CAS  Google Scholar 

  107. Kim Y, Lee KS, Jung KJ, Han J, Kim JS, Suh JS. Halo sign on high resolution CT: findings in spectrum of pulmonary diseases with pathologic correlation. J Comput Assist Tomogr. 1999;23(4):622–6.

    Article  PubMed  CAS  Google Scholar 

  108. Kwon WJ, Jeong YJ, Kim KI, et al. Computed tomographic features of pulmonary septic emboli: comparison of causative microorganisms. J Comput Assist Tomogr. 2007;31(3):390–4.

    Article  PubMed  Google Scholar 

  109. Mylonakis E, Calderwood SB. Infective endocarditis in adults. N Engl J Med. 2001;345(18):1318–30.

    Article  PubMed  CAS  Google Scholar 

  110. Kizer KW, Goodman PC. Radiographic manifestations of venous air embolism. Radiology. 1982;144(1):35–9.

    PubMed  CAS  Google Scholar 

  111. Orebaugh SL. Venous air embolism: clinical and experimental considerations. Crit Care Med. 1992;20(8):1169–77.

    Article  PubMed  CAS  Google Scholar 

  112. Gallagher TJ. Scuba diving accidents: decompression sickness, air embolism. J Fla Med Assoc. 1997;84(7):446–51.

    PubMed  CAS  Google Scholar 

  113. Woodring JH, Fried AM. Nonfatal venous air embolism after contrast-enhanced CT. Radiology. 1988;167(2):405–7.

    PubMed  CAS  Google Scholar 

  114. Hill AD, Toner ME, FitzGerald MX. Talc lung in a drug abuser. Ir J Med Sci. 1990;159(5):147–8.

    Article  PubMed  CAS  Google Scholar 

  115. Bendeck SE, Leung AN, Berry GJ, Daniel D, Ruoss SJ. Cellulose granulomatosis presenting as centrilobular nodules: CT and histologic findings. Am J Roentgenol. 2001;177(5):1151–3.

    CAS  Google Scholar 

  116. Schmidt RA, Glenny RW, Godwin JD, Hampson NB, Cantino ME, Reichenbach DD. Panlobular emphysema in young intravenous Ritalin abusers. Am Rev Respir Dis. 1991;143(3):649–56.

    PubMed  CAS  Google Scholar 

  117. Jorens PG, Van Marck E, Snoeckx A, Parizel PM. Nonthrombotic pulmonary embolism. Eur Respir. 2009;34(2):452–74.

    Article  CAS  Google Scholar 

  118. Nan DN, Fernandez-Ayala M, Iglesias L, Garcia-Palomo D, Parra JA, Farinas MC. Talc granulomatosis: a differential diagnosis of interstitial lung disease in HIV patients. Chest. 2000;118(1):258–60.

    Article  PubMed  CAS  Google Scholar 

  119. Fields TA, McCall SJ, Reams BD, Roggli VL, Palmer SM, Howell DN. Pulmonary embolization of microcrystalline cellulose in a lung transplant recipient. J Heart Lung Transplant Off Public Int Soc Heart Transplant. 2005;24(5):624–7.

    Article  Google Scholar 

  120. Diaz-Ruiz MJ, Gallardo X, Castaner E, Mata JM, Catala J, Ferreres JC. Cellulose granulomatosis of the lungs. Eur Radiol. 1999;9(6):1203–4.

    Article  PubMed  CAS  Google Scholar 

  121. Ward S, Heyneman LE, Reittner P, Kazerooni EA, Godwin JD, Muller NL. Talcosis associated with IV abuse of oral medications: CT findings. Am J Roentgenol. 2000;174(3):789–93.

    CAS  Google Scholar 

  122. Demeter S, Raymond GS, Puttagunta L, Barrie JR. Residents’ corner: answer to case of the month #66: intravenous pulmonary talcosis with complicating massive fibrosis. Can Assoc Radiol J. 1999;50(6):413–15.

    Google Scholar 

  123. Stern EJ, Frank MS, Schmutz JF, Glenny RW, Schmidt RA, Godwin JD. Panlobular pulmonary emphysema caused by i.v. injection of methylphenidate (Ritalin): findings on chest radiographs and CT scans. Am J Roentgenol. 1994;162(3):555–60.

    CAS  Google Scholar 

  124. Parisi DM, Koval K, Egol K. Fat embolism syndrome. Am J Orthop. 2002;31(9):507–12.

    PubMed  Google Scholar 

  125. Koessler MJ, Fabiani R, Hamer H, Pitto RP. The clinical relevance of embolic events detected by transesophageal echocardiography during cemented total hip arthroplasty: a randomized clinical trial. Anesth Analg. 2001;92(1):49–55.

    Article  PubMed  CAS  Google Scholar 

  126. King MB, Harmon KR. Unusual forms of pulmonary embolism. Clin Chest Med. 1994;15(3):561–80.

    PubMed  CAS  Google Scholar 

  127. Dudney TM, Elliott CG. Pulmonary embolism from amniotic fluid, fat, and air. Prog Cardiovasc Dis. 1994;36(6):447–74.

    Article  PubMed  CAS  Google Scholar 

  128. Richards RR. Fat embolism syndrome. Can J Surg. 1997;40(5):334–9.

    PubMed  CAS  Google Scholar 

  129. Muller NL, Fraser RS, Colman NC, Pare PD. Radiologic diagnosis of diseases of the chest. 1st ed. Philladelpia: Saunders; 2001.

    Google Scholar 

  130. Davies S. Amniotic fluid embolus: a review of the literature. Can J Anaesth. 2001;48(1):88–98.

    Google Scholar 

  131. Clark SL. New concepts of amniotic fluid embolism: a review. Obstet Gynecol Surv. 1990;45(6):360–8.

    Article  PubMed  CAS  Google Scholar 

  132. Clark SL, Hankins GD, Dudley DA, Dildy GA, Porter TF. Amniotic fluid embolism: analysis of the national registry. Am J Obstet Gynecol. 1995;172(4 Part 1):1158–67; discussion 1159–67.

    Google Scholar 

  133. Karetzky M, Ramirez M. Acute respiratory failure in pregnancy: an analysis of 19 cases. Medicine (Baltimore). 1998;77(1):41–9.

    Article  CAS  Google Scholar 

  134. Pluymakers C, De Weerdt A, Jacquemyn Y, Colpaert C, Van de Poel E, Jorens PG. Amniotic fluid embolism after surgical trauma: two case reports and review of the literature. Resuscitation. 2007;72(2):324–32.

    Google Scholar 

  135. Fidler JL, Patz EF Jr, Ravin CE. Cardiopulmonary complications of pregnancy: radiographic findings. Am J Roentgenol. 1993;161(5):937–42.

    CAS  Google Scholar 

  136. Yi CA, Lee KS, Choe YH, Han D, Kwon OJ, Kim S. Computed tomography in pulmonary artery sarcoma: distinguishing features from pulmonary embolic disease. J Comput Assist Tomogr. 2004;28(1):34–9.

    Article  PubMed  Google Scholar 

  137. Cox JE, Chiles C, Aquino SL, Savage P, Oaks T. Pulmonary artery sarcomas: a review of clinical and radiologic features. J Comput Assist Tomogr. 1997;21(5):750–5.

    Article  PubMed  CAS  Google Scholar 

  138. Baker PB, Goodwin RA. Pulmonary artery sarcomas: a review and report of a case. Arch Pathol Lab Med. 1985;109(1):35–9.

    PubMed  CAS  Google Scholar 

  139. Olsson HE, Spitzer RM, Erston WF. Primary and secondary pulmonary artery neoplasia mimicking acute pulmonary embolism. Radiology. 1976;118(1):49–53.

    PubMed  CAS  Google Scholar 

  140. Blackmon SH, Rice DC, Correa AM, et al. Management of primary pulmonary artery sarcomas. Ann Thorac Surg. 2009;87(3):977–84.

    Article  PubMed  Google Scholar 

  141. Dennie CJ, Veinot JP, McCormack DG, Rubens FD. Intimal sarcoma of the pulmonary arteries seen as a mosaic pattern of lung attenuation on high-resolution CT. Am J Roentgenol. 2002;178(5):1208–10.

    Google Scholar 

  142. Smith WS, Lesar MS, Travis WD, et al. MR and CT findings in pulmonary artery sarcoma. J Comput Assist Tomogr. 1989;13(5):906–9.

    Article  PubMed  CAS  Google Scholar 

  143. Weinreb JC, Davis SD, Berkmen YM, Isom W, Naidich DP. Pulmonary artery sarcoma: evaluation using Gd-DTPA. J Comput Assist Tomogr. 1990;14(4):647–9.

    Article  PubMed  CAS  Google Scholar 

  144. Thurer RL, Thorsen A, Parker JA, Karp DD. FDG imaging of a pulmonary artery sarcoma. Ann Thorac Surg. 2000;70(4):1414–5.

    Article  PubMed  CAS  Google Scholar 

  145. Chong S, Kim TS, Kim BT, Cho EY, Kim J. Pulmonary artery sarcoma mimicking pulmonary thromboembolism: integrated FDG PET/CT. Am J Roentgenol. 2007;188(6):1691–3.

    Article  Google Scholar 

  146. Simonneau G, Galie N, Rubin LJ, et al. Clinical classification of pulmonary hypertension. J Am Coll Cardiol. 2004;43(12 Suppl S):5S–12S.

    Article  PubMed  Google Scholar 

  147. Leinonen H, Pohjola-Sintonen S, Krogerus L. Pulmonary veno-occlusive disease. Acta Med Scand. 1987;221(3):307–10.

    Article  PubMed  CAS  Google Scholar 

  148. Morassut PA, Walley VM, Smith CD. Pulmonary veno-occlusive disease and the CREST variant of scleroderma. Can J Cardiol. 1992;8(10):1055–8.

    PubMed  CAS  Google Scholar 

  149. Veeraraghavan S, Koss MN, Sharma OP. Pulmonary veno-occlusive disease. Curr Opin Pulm Med. 1999;5(5):310–3.

    Article  PubMed  CAS  Google Scholar 

  150. Kishida Y, Kanai Y, Kuramochi S, Hosoda Y. Pulmonary venoocclusive disease in a patient with systemic lupus erythematosus. J Rheumatol. 1993;20(12):2161–2.

    PubMed  CAS  Google Scholar 

  151. Hourseau M, Capron F, Nunes H, Godmer P, Martin A, Kambouchner M. Pulmonary veno-occlusive disease in a patient with HIV infection: a case report with autopsy findings. Ann Pathol. 2002;22(6):472–5.

    PubMed  Google Scholar 

  152. Hamada K, Teramoto S, Narita N, Yamada E, Teramoto K, Kobzik L. Pulmonary veno-occlusive disease in pulmonary Langerhans’ cell granulomatosis. Eur Respir. 2000;15(2):421–3.

    Article  CAS  Google Scholar 

  153. Johnson SR, Patsios D, Hwang DM, Granton JT. Pulmonary veno-occlusive disease and scleroderma associated pulmonary hypertension. J Rheumatol. 2006;33(11):2347–50.

    PubMed  Google Scholar 

  154. Montani D, Achouh L, Dorfmuller P, et al. Pulmonary veno-occlusive disease: clinical, functional, radiologic, and hemodynamic characteristics and outcome of 24 cases confirmed by histology. Medicine (Baltimore). 2008;87(4):220–33.

    Article  Google Scholar 

  155. Holcomb BW Jr, Loyd JE, Ely EW, Johnson J, Robbins IM. Pulmonary veno-occlusive disease: a case series and new observations. Chest. 2000;118(6):1671–9.

    Article  PubMed  Google Scholar 

  156. Pietra GG, Capron F, Stewart S, et al. Pathologic assessment of vasculopathies in pulmonary hypertension. J Am Coll Cardiol. 2004;43(12 Suppl S):25S–32S.

    Article  PubMed  Google Scholar 

  157. Lantuejoul S, Sheppard MN, Corrin B, Burke MM, Nicholson AG. Pulmonary veno-occlusive disease and pulmonary capillary hemangiomatosis: a clinicopathologic study of 35 cases. Am J Surg Pathol. 2006;30(7):850–7.

    Article  PubMed  Google Scholar 

  158. Wagenvoort CA, Beetstra A, Spijker J. Capillary haemangiomatosis of the lungs. Histopathology. 1978;2(6):401–6.

    Article  PubMed  CAS  Google Scholar 

  159. Tron V, Magee F, Wright JL, Colby T, Churg A. Pulmonary capillary hemangiomatosis. Hum Pathol. 1986;17(11):1144–50.

    Article  PubMed  CAS  Google Scholar 

  160. Eltorky MA, Headley AS, Winer-Muram H, Garrett HE Jr, Griffin JP. Pulmonary capillary hemangiomatosis: a clinicopathologic review. Ann Thorac Surg. 1994;57(3):772–6.

    Article  PubMed  CAS  Google Scholar 

  161. Rabiller A, Jais X, Hamid A, et al. Occult alveolar haemorrhage in pulmonary veno-occlusive disease. Eur Respir. 2006;27(1):108–13.

    Article  CAS  Google Scholar 

  162. Resten A, Maitre S, Humbert M, et al. Pulmonary hypertension: CT of the chest in pulmonary venoocclusive disease. Am J Roentgenol. 2004;183(1):65–70.

    Google Scholar 

  163. Rambihar VS, Fallen EL, Cairns JA. Pulmonary veno-occlusive disease: antemortem diagnosis from roentgenographic and hemodynamic findings. Can Med Assoc J. 1979;120(12):1519–22.

    PubMed  CAS  Google Scholar 

  164. Montani D, O’Callaghan DS, Savale L, et al. Pulmonary veno-occlusive disease: recent progress and current challenges. Respir Med. 2010;104(Suppl 1):S23–32.

    Article  PubMed  Google Scholar 

  165. Valdes L, Gonzalez-Juanatey JR, Alvarez D, et al. Diagnosis of pulmonary veno-occlusive disease: new criteria for biopsy. Respir Med. 1998;92(7):979–83.

    Article  PubMed  CAS  Google Scholar 

  166. Cassart M, Gevenois PA, Kramer M, et al. Pulmonary venoocclusive disease: CT findings before and after single-lung transplantation. Am J Roentgenol. 1993;160(4):759–60.

    CAS  Google Scholar 

  167. Swensen SJ, Tashjian JH, Myers JL, et al. Pulmonary venoocclusive disease: CT findings in eight patients. Am J Roentgenol. 1996;167(4):937–40.

    CAS  Google Scholar 

  168. Dufour B, Maitre S, Humbert M, Capron F, Simonneau G, Musset D. High-resolution CT of the chest in four patients with pulmonary capillary hemangiomatosis or pulmonary venoocclusive disease. Am J Roentgenol. 1998;171(5):1321–4.

    CAS  Google Scholar 

  169. Resten A, Maitre S, Musset D. CT imaging of peripheral pulmonary vessel disease. Eur Radiol. 2005;15(10):2045–56.

    Article  PubMed  Google Scholar 

  170. Van Praagh S, Carrera ME, Sanders S, Mayer JE Jr, Van Praagh R. Partial or total direct pulmonary venous drainage to right atrium due to malposition of septum primum: anatomic and echocardiographic findings and surgical treatment: a study based on 36 cases. Chest. 1995;107(6):1488–98.

    Article  PubMed  Google Scholar 

  171. Rajiah P, Kanne JP. Computed tomography of pulmonary venous variants and anomalies. J Cardiovasc Comput Tomogr. 2010;4(3):155–63.

    Article  PubMed  Google Scholar 

  172. Gustafson RA, Warden HE, Murray GF, Hill RC, Rozar GE. Partial anomalous pulmonary venous connection to the right side of the heart. J thorac cardiovasc surg. 1989;98(5 Part 2):861–8.

    PubMed  CAS  Google Scholar 

  173. Woodring JH, Howard TA, Kanga JF. Congenital pulmonary venolobar syndrome revisited. Radiographics. 1994;14(2):349–69.

    PubMed  CAS  Google Scholar 

  174. Shah DC, Haissaguerre M, Jais P. Toward a mechanism-based understanding of atrial fibrillation. J Cardiovasc Electrophysiol. 2001;12(5):600–1.

    Article  PubMed  CAS  Google Scholar 

  175. Ravenel JG, McAdams HP. Pulmonary venous infarction after radiofrequency ablation for atrial fibrillation. Am J Roentgenol. 2002;178(3):664–6.

    Google Scholar 

  176. Scharf C, Sneider M, Case I, et al. Anatomy of the pulmonary veins in patients with atrial fibrillation and effects of segmental ostial ablation analyzed by computed tomography. J Cardiovasc Electrophysiol. 2003;14(2):150–5.

    Article  PubMed  Google Scholar 

  177. Robbins IM, Colvin EV, Doyle TP, et al. Pulmonary vein stenosis after catheter ablation of atrial fibrillation. Circulation. 1998;98(17):1769–75.

    PubMed  CAS  Google Scholar 

  178. Lacomis JM, Wigginton W, Fuhrman C, Schwartzman D, Armfield DR, Pealer KM. Multi-detector row CT of the left atrium and pulmonary veins before radio-frequency catheter ablation for atrial fibrillation. Radiographics. 2003;23 Spec No:S35–48; discussion S48–50.

    Google Scholar 

  179. Thakur RK, Klein GJ, Yee R, Zardini M. Embolic complications after radiofrequency catheter ablation. Am J Cardiol. 1994;74(3):278–9.

    Article  PubMed  CAS  Google Scholar 

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Peña, E., Dennie, C., Chandy, G. (2012). Non-Thrombotic Vascular Diseases of the Chest. In: Kanne, J. (eds) Clinically Oriented Pulmonary Imaging. Respiratory Medicine. Humana Press. https://doi.org/10.1007/978-1-61779-542-8_8

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