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Nutritional Supplements for Endurance Athletes

  • Chapter
Nutritional Supplements in Sports and Exercise

Abstract

Athletes engaged in heavy endurance training often seek additional nutritional strategies to help maximize performance. Specific nutritional supplements exist to combat certain factors that limit performance beginning with a sound everyday diet. Research has further demonstrated that safe, effective, legal supplements are in fact available for today’s endurance athletes. Several of these supplements are marketed not only to aid performance but also to combat the immunosuppressive effects of intense endurance training. It is imperative for each athlete to research the legality of certain supplements for their specific sport or event. Once the legality has been established, it is often up to each individual athlete to decipher the ethics involved with ingesting nutritional supplements with the sole intent of improving performance.

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References

  1. Bell DG, Jacobs I. Combined caffeine and ephedrine ingestion improves run times of Canadian Forces Warrior Test. Aviat Space Environ Med 1999;70:325–328.

    CAS  Google Scholar 

  2. Blomstrand E, Hassem P, Ekblom B, Newsholme EA. Administration of branched-chain amino acids during sustained exercise-effects on performance and plasma concentration of some amino acids. Eur J Appl Physiol 1991;63:83–88.

    Article  CAS  Google Scholar 

  3. Bridge CA, Jones MA. The effect of caffeine ingestion on 8 km run performance in a field setting. J Sports Sci 2006;24:433–439.

    Article  CAS  Google Scholar 

  4. Erickson MA. Effects of caffeine, fructose, and glucose ingestion on muscle glycogen utilization during exercise. Med Sci Sports Exerc 1987;19:579–583.

    CAS  Google Scholar 

  5. Kreider RB, Miller GW, Williams MH, Somma CT, Nasser TA. Effects of phosphate loading on oxygen uptake, ventilatory anaerobic threshold, and run performance. Med Sci Sports Exerc 1990;22:250–256.

    CAS  Google Scholar 

  6. Mittleman KD, Ricci MR, Bailey SP. Branched-chain amino acids prolong exercise during heat stress in men and women. Med Sci Sports Exerc 1998;30:83–91.

    CAS  Google Scholar 

  7. Saunders MJ, Kane MD, Todd MK. Effects of a carbohydrate-protein beverage on cycling endurance and muscle damage. Med Sci Sports Exerc 2004;36:1233–1238.

    Article  CAS  Google Scholar 

  8. Coyle EF, Montain SJ. Benefits of fluid replacement with carbohydrate during exercise. Med Sci Sports Exerc 1992;24:S324–S330.

    CAS  Google Scholar 

  9. Armstrong LE, Costill DL, Fink WJ. Influence of diuretic-induced dehydration on competitive running performance. Med Sci Sports Exerc 1985;17:456–461.

    Article  CAS  Google Scholar 

  10. Sutton JR, Bar-Or O. Thermal illness in fun running. Am Heart J 1980;100:778–781.

    Article  CAS  Google Scholar 

  11. Coyle EF. Substrate utilization during exercise in active people. Am J Clin Nutr 1995;61(Suppl):968S–979S.

    CAS  Google Scholar 

  12. Thibault G. Ahead of the pack. Training Cond 2006;16:25–31.

    Google Scholar 

  13. Kreider R, Fry AC, O'Toole ML (eds). Overtraining in Sport. Human Kinetics, Champaign, IL, 1998.

    Google Scholar 

  14. Carli G. Changes in the exercise-induced hormone response to branched chain amino acid administration. Eur J Physiol Occup Physiol 1992;64:272–277.

    Article  CAS  Google Scholar 

  15. Cade JR. Dietary intervention and training in swimmers. Eur J Physiol Occup Physiol 1997;63:210–215.

    Article  Google Scholar 

  16. Kreider RB. Dietary supplements and the promotion of muscle growth with resistance exercise. Sports Med 1999;27:97–110.

    Article  CAS  Google Scholar 

  17. Komi PV (ed). Strength and Power in Sport. Blackwell Scientific, Cambridge, MA, 1992.

    Google Scholar 

  18. Brand-Miller J, Wolever TMS, Colagiuri S, Foster-Powell K (eds). The Glucose Revolution. Marlowe, New York, 1999.

    Google Scholar 

  19. Coyle EF, Montain SJ. Carbohydrate and fluid ingestion during exercise: are there trade-offs? Med Sci Sports Ex 1992;24:671–678.

    CAS  Google Scholar 

  20. Noakes TD, Myburgh KH, Du Plessia J, et al. Metabolic rate, not percent dehydration, predicts rectal temperature in marathon runners. Med Sci Sports Exerc 1991;23:443–449.

    Google Scholar 

  21. Bergstrom J, Hermansen L, Hultman E, Saltin B. Diet, muscle glycogen and physical performance. Acta Physiol Scand 1967;71:140–150.

    Article  CAS  Google Scholar 

  22. Balsom PD, Gaitanos GC, Soderlund K, Ekblom B. High-intensity exercise and muscle glycogen availability in humans. Acta Physiol Scand 1999;165:337–345.

    Article  CAS  Google Scholar 

  23. Volek JS. Influence of nutrition on responses to resistance training. Med Sci Sports Exerc 2004;36:689–696.

    Article  Google Scholar 

  24. Ivy JL, Res PT, Sprague RC, Widzer MO. Effect of a carbohydrate-protein supplement on endurance performance during exercise of varying intensity. Int J Sport Nutr Exerc Metab 2003;13:382–395.

    CAS  Google Scholar 

  25. Anderson LL, Tufekovic G, Zebis MK, et al. The effect of resistance training combined with timed ingestion of protein on muscle fiber size and muscle strength. Metabolism 2005;54:151–156.

    Article  Google Scholar 

  26. Dangin M, Boirie Y, Garcia-Rodenas C, et al. The digestion rate of protein is an independent regulating factor of postprandial protein retention. Am J Physiol Endocrinol Metab 2001;280:E340–E348.

    CAS  Google Scholar 

  27. Ivy JL, Portman R (eds) The Performance Zone. Basic Health Publications, North Bergen, NJ, 2004.

    Google Scholar 

  28. Costill D, Hargreaves M. Carbohydrate nutrition and fatigue. Sports Med 1992;13:86–92.

    Article  CAS  Google Scholar 

  29. Ivy JL. Muscle glycogen synthesis before and after exercise. Sports Med 1991;11:6–11.

    Article  CAS  Google Scholar 

  30. Houston M (ed). Biochemistry Primer for Exercise Science. Human Kinetics, Champaign, IL, 1995.

    Google Scholar 

  31. Ivy JL. Glycogen resynthesis after exercise: effect of carbohydrate intake. Int J Sports Med 1998;19:S142–S145.

    Article  CAS  Google Scholar 

  32. Haymond M. Hypoglycemia in infants and children. Endocrinol Metab Clin North Am 1989;18:211–252.

    CAS  Google Scholar 

  33. Gastelu D, Hatfield F (eds). Nutrition for Maximum Performance. Avery, Garden City Park, NY, 1997.

    Google Scholar 

  34. Blom P, Hostmark A, Vaage O, Kardel K, Maehlum S. Effects of different post-exercise sugar diets on the rate of muscle glycogen synthesis. Med Sci Sports Exerc 1987;19:491–496.

    CAS  Google Scholar 

  35. Burke L, Collier G, Hargreaves M. Muscle glycogen storage after prolonged exercise: effect of the glycemic index of carbohydrate feedings. J Appl Physiol 1993;75:1019–1023.

    CAS  Google Scholar 

  36. Jentjens RLPG, van Loon LJC, Mann CH, Wagenmakers AJM, Jeukendrup AE. Addition of protein and amino acids to carbohydrates does not enhance post-exercise muscle glycogen synthesis. J Appl Physiol 2001;91:839–846.

    Google Scholar 

  37. Tarnopolsky MA, Bosman M, Macdonald JR, Vandeputte D, Martin J, Roy BD. Post-exercise protein-carbohydrate and carbohydrate supplements increase muscle glycogen in men and women. J Appl Physiol 1997;83:1877–1883.

    CAS  Google Scholar 

  38. Evans WJ. Protein nutrition and resistance exercise. Can J Appl Physiol 2001;26(Suppl):S141–S152.

    Google Scholar 

  39. Ivy JL, Katz AL, Dutler CL, Sherman WM, Cyyle EF. Muscle glycogen synthesis after exercise: effect of time of carbohydrate ingestion. J Appl Physiol 1988;64:1480–1485.

    CAS  Google Scholar 

  40. Garetto OP, Richter EA, Goodman MN, Ruderman NB. Enhanced muscle glucose metabolism after exercise in the rat: the two phases. Am J Physiol 1984;246:E471–E475.

    CAS  Google Scholar 

  41. Miller SL, Tipton KD, Chinkes DL. Independent and combined effects of amino acids and glucose after resistance exercise. Med Sci Sports Exerc 2003;35:449–455.

    Article  CAS  Google Scholar 

  42. Williams MH. The Ergogenics Edge. 1st ed. Human Kinetics, Champaign, IL, 1998.

    Google Scholar 

  43. Cade R, Conte M. Effects of phosphate loading on 2,3-diphosphoglycerate and maximum oxygen uptake. Med Sci Sports Exerc 1984;16:263–268.

    CAS  Google Scholar 

  44. Antonio J, Stout J. Supplements for Endurance Athletes. Human Kinetics, Champaign, IL, 2002.

    Google Scholar 

  45. Blomstrand E, Celsing F, Newsholme EA. Changes in plasma concentrations of aromatic and branched-chain amino acids during sustained exercise in man and their possible role in fatigue. Acta Physiol Scand 1988;1:115–121.

    Article  Google Scholar 

  46. Castell LM, Yamamoto T, Phoenix J, Newsholme EA. The role of tryptophan in fatigue in different conditions of stress. Adv Exp Med Biol 1999;467:697–704.

    CAS  Google Scholar 

  47. Davis JM. Carbohydrates, branched-chain amino acids, and endurance: the central fatigue hypothesis. Int J Sport Nutr 1995;5(Suppl):S29–S38.

    Google Scholar 

  48. Hassmen P, Blomstrand E, Ekblom B, Newsholme EA. Branched-chain amino acid supplementation during 30-km competitive run: mood and cognitive performance. Nutrition 1994;10:405–410.

    CAS  Google Scholar 

  49. Tanaka H, West KA, Duncan GE, Bassett DRJ. Changes in plasma tryptophan/branched chain amino acid ration in responses to training volume variation. Int J Sport Nutr 1997;18:270–275.

    Article  CAS  Google Scholar 

  50. Talbott SM, Hughes K. The Health Professional's Guide to Dietary Supplements. 1st ed. Lippincott Williams & Wilkins, Philadelphia, 2007.

    Google Scholar 

  51. Gastmann UA, Lehmann MJ. Overtraining and the BCAA hypothesis. Med Sci Sports Exerc 1998;30:1173–1178.

    Article  CAS  Google Scholar 

  52. Van Hall G, Raaymakers JS, Saris WH, Wagenmakers AJ. Ingestion of branched-chain amino acids and tryptophan during sustained exercise in man: failure to affect performance. J Physiol 1995;486:789–794.

    Google Scholar 

  53. Davis JM, Bailey SP, Woods JA, Galiano FJ, Hamilton MT, Bartoli WP. Effects of carbohydrate feedings on plasma free tryptophan and branched-chain amino acids during prolonged cycling. Eur J Appl Physiol Occup Physiol 1992;65:513–519.

    Article  CAS  Google Scholar 

  54. Costill DL, Dalsky GP, Fink WJ. Effects of caffeine ingestion on metabolism and exercise performance. Med Sci Sports Exerc 1978;10:155–158.

    CAS  Google Scholar 

  55. Spreit LL, MaClean DA, Dyck DJ, Hultmant E. Caffeine ingestions and muscle metabolism during prolonged exercise in humans. Am J Physiol 1992;262:E891–E898.

    Google Scholar 

  56. Schneiker KT, Bishop D, Dawson B, Hackett LP. Effects of caffeine on prolonged intermittent-sprint ability in team-sport athletes. Med Sci Sports Exerc 2006;38:578–585.

    Article  CAS  Google Scholar 

  57. Namdar M, Koepfli P, Grathwohl R, et al. Caffeine decreases exercise-induced myocardial flow reserve. J Am Coll Cardiol 2006;47:405–410.

    Article  CAS  Google Scholar 

  58. Bell DG, McLennan TM, Sabiston CM. Effect of ingesting caffeine and ephedrine on 10-km run performance. Med Sci Sports Exerc 2002;34:344–349.

    Article  CAS  Google Scholar 

  59. Blumenthal M, Busse WR, Goldberg A (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Integrative Medicine Communications, Boston, 1998.

    Google Scholar 

  60. Jimenez C, Melin B, Doulmann N, Allevard AM, Launay JC, Savourey G. Plasma volume changes during and after acute variations of body hydration level in humans. Eur J Appl Physiol Occup Physiol 1999;80:1–8.

    Article  CAS  Google Scholar 

  61. Wagner DR. Hyperhydrating with glycerol: implications for athletic performance. J Am Diet Assoc 1999;99:207–212.

    Article  CAS  Google Scholar 

  62. Lyons TP, Riedesel ML, Meuli LE, Chick TW. Effects of glycerol-induced hyperhydration prior to exercise in the heat on sweating and core temperature. Med Sci Sports Exerc 1990;22:477–483.

    CAS  Google Scholar 

  63. Montner P, Stark DM, Riedesel ML. Pre-exercise glycerol hydration improves cycling endurance time. Int J Sports Med 1996;17:27–33.

    Article  CAS  Google Scholar 

  64. Arnall DA, Goforth HWJ. Failure to reduce body water loss in cold-water immersion by glycerol ingestion. Undersea Hyperb Med 1993;20:309–320.

    CAS  Google Scholar 

  65. Harris RC, Viru M, Greenhaff PL, Hultman E. The effect of oral creatine supplementation on running performance during maximal short term exercise in man. J Physiol 1993;467:74P.

    Google Scholar 

  66. Smith JC, Stephens DP, Hall EL, Jackson AW, Earnest CP. Effect of oral creatine ingestion on parameters of the work rate-time relationship and time to exhaustion in high-intensity cycling. Eur J Appl Physiol 1998;77:360–365.

    Article  CAS  Google Scholar 

  67. Nelson A, Day R, Glickman-Weiss E, Hegstad M, Sampson B. Creatine supplementation alters the response to a graded cycle ergometer test. Eur J Appl Physiol 2000;83:89–94.

    Article  CAS  Google Scholar 

  68. Stout J, Eckerson J, Ebersole K, et al. Effect of creatine loading on neuromuscular fatigue threshold. J Appl Physiol 2000;88:109–112.

    CAS  Google Scholar 

  69. Bangsbo J, Gollnick PD, Graham TE. Anaerobic energy production and O2 deficit-debt relationship during exhaustive exercise in humans. J Physiol 1990;422:539–559.

    CAS  Google Scholar 

  70. Wallimann T, Wyss M, Brdiczka D, Nicolay K, Eppenberger HM. Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the `phosphocreatine circuit’ for cellular energy homeostasis. Biochem J 1992;281:21–40.

    CAS  Google Scholar 

  71. Mackinnon LT. Exercise and natural killer cells: what is the relationship? Sports Med 1989;7:141–149.

    Article  CAS  Google Scholar 

  72. McCarthy DA, Dale MM. The leucocytosis of exercise: a review and model. Sports Med 1988;6:333–363.

    Article  CAS  Google Scholar 

  73. Brahmi Z, Thomas JE, Park M, Dowdeswell IRG. The effect of acute exercise on natural killer cell activity of trained and sedentary subjects. J Clin Immunol 1985;5:321.

    Article  CAS  Google Scholar 

  74. Berning JR. Energy intake, diet and muscle wasting. In: Kreider RB, Fry AC, O'Toole ML (eds) Overtraining in Sport (pp 275–288). Human Kinetics, Champaign, IL, 1998.

    Google Scholar 

  75. Haff GG, Lehmkuhl MJ, McCoy LB, Stone MH. Carbohydrate supplementation and resistance training. J Strength Cond Res 2003;7:187–196.

    Google Scholar 

  76. Flakoll PJ, Judy T, Flinn K, Carr C, Flinn S. Postexercise protein supplementation improves health and muscle soreness during basic military training in marine recruits. J Appl Physiol 2001;96:951–956.

    Article  Google Scholar 

  77. Buckley J. Effect of oral bovine colostrum supplement (Intact) on running performance. In: Proceedings of the Australian Conference of Science and Medicine in Sport (p 79).

    Google Scholar 

  78. Brinkworth GD, Buckley JD, Bourdon PC, Gulbin JP, David A. Oral bovine colostrum supplementation enhances buffer capacity but not rowing performance in elite female rowers. Int J Sport Nutr Exerc Metab 2002;12:349–365.

    Google Scholar 

  79. Bolke E, Jehle PM, Hausmann F, et al. Preoperative oral application of immunoglobulin-enriched colostrum milk and mediator response during abdominal surgery. Shock 2002;17:9–12.

    Article  Google Scholar 

  80. Playford RJ, MacDonald CE, Calnan DP, et al. Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability. Clin Sci (Lond) 2001;100:627–633.

    Article  CAS  Google Scholar 

  81. Khan Z, Macdonald C, Wicks AC, et al. Use of the “nutriceutical,” bovine colostrum, for the treatment of distal colitis: results from an initial study. Aliment Pharmacol Ther 2002;16:1917–1922.

    Article  CAS  Google Scholar 

  82. Ardawi MSM, Newsholme EA. Glutamine metabolism in lymphocytes of rats. Biochem J 1983;212:835.

    CAS  Google Scholar 

  83. Ardawi MSM, Newsholme EA. Metabolism in lymphocytes and its importance in immune response. Essays Biochem 1985;21:1.

    CAS  Google Scholar 

  84. Carli F, Webster J, Ramachandra V, et al. Aspects of protein metabolism after elective surgery in patients receiving constant nutritional support. Clin Sci (Colch) 1990;78:621–628.

    CAS  Google Scholar 

  85. Williams JZ, Abumrad N, Barbul A. Effect of a specialized amino acid mixture on human collagen deposition. Ann Surg 2002;236:369–374.

    Article  Google Scholar 

  86. Vukovich MD, Sharp RL, Kesl LD, Schaulis DL, King DS. Effects of a low-dose amino acid supplement on adaptations to cycling training in untrained individuals. Int J Sport Nutr 1997;7:298–309.

    CAS  Google Scholar 

  87. Castell LM, Poortmans JR, Newsholme EA. Does glutamine have a role in reducing infections in athletes? Euro J Appl Physiol 1996;73:488–490.

    Article  CAS  Google Scholar 

  88. Des Robert C, Le Bacquer O, Piloquet H, Roze JC, Darmaun D. Acute effects of intravenous glutamine supplementation on protein metabolism in very low birth weight infants: a stable isotope study. Pediatr Res 2002;51:87–93.

    Article  CAS  Google Scholar 

  89. Yoshida S, Kaibara A, Ishibashi N, Shirouzu K. Glutamine supplementation in cancer patients. Nutrition 2001;17:766–768.

    Article  CAS  Google Scholar 

  90. Klimberg VS, Nwokedi E, Hutchins LF, et al. Glutamine facilitates chemotherapy while reducing toxicity. JPEN J Parenter Enteral Nutr 1992;16:83S–87S.

    Article  CAS  Google Scholar 

  91. Barbosa E, Moreira EA, Goes JE, Faintuch J. Pilot study with a glutamine-supplemented enteral formula in critically ill infants. Rev Hosp Clin Fac Med Sao Paulo 1999;54:21–24.

    CAS  Google Scholar 

  92. Khaled S, Brun JF, Micallef JP, et al. Serum zinc and blood rheology in sportsmen (football players). Clin Hemorheol Microcirc 1997;17:47–58.

    CAS  Google Scholar 

  93. Om A, Chung K. Dietary zinc deficiency alters 5 alpha-reduction and aromatization of testosterone and androgen estrogen receptors in rat liver. J Nutr 1996;126:842–848.

    CAS  Google Scholar 

  94. Nieman DC. Nutrition, exercise, and immune system function. Clin Sports Med 1999;18:537–548.

    Article  CAS  Google Scholar 

  95. Van Loan MD, Sutherland B, Lowe NM, Turnland JR, King JC. The effects of zinc depletion on peak force and total work of knee and shoulder extensor and flexor muscles. Int J Sport Nutr 1999;9:125–135.

    Google Scholar 

  96. Eby GA. Zinc ion availability: the determinant of efficacy in zinc lozenge treatment of common colds. J Antimicrob Chemother 1997;40:483–493.

    CAS  Google Scholar 

  97. Cordova A, Navas FJ. Effect of training on zinc metabolism: changes in serum and sweat zinc concentrations in sportsmen. Ann Nutr Metab 1998;42:274–282.

    Article  CAS  Google Scholar 

  98. Kilic M, Baltaci AK, Gunay M, Gokbel H, Okudan N, Cicioglu I. The effect of exhaustion exercise on thyroid hormones and testosterone levels of elite athletes receiving oral zinc. Neuro Endocrinol Lett 2006;27:247–252.

    CAS  Google Scholar 

  99. Peake JM, Gerrard DF, Griffin JF. Plasma zinc and immune markers in runners in response to a moderate increase in training volume. Int J Sports Med 2003;24:212–216.

    Article  CAS  Google Scholar 

  100. Gisolfi CV, Lamb DR (eds). Fluid Homeostasis During Exercise (Perspectives in Exercise and Sports Medicine). Benchmark Press, Indianapolis, 1990.

    Google Scholar 

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  1. Department of Health & Kinesiology, Texas A&M University in College Station, TX

    Christopher J. Rasmussen MS, CSCS

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  1. Christopher J. Rasmussen MS, CSCS
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© 2008 Humana Press, a part of Springer Science+Business Media, LLC

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Rasmussen, C.J. (2008). Nutritional Supplements for Endurance Athletes. In: Nutritional Supplements in Sports and Exercise. Humana Press. https://doi.org/10.1007/978-1-59745-231-1_11

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