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Circadian Regulation of Renal Function

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Circadian Clocks: Role in Health and Disease

Part of the book series: Physiology in Health and Disease ((PIHD))

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Abstract

The biological clock allows living organisms to anticipate periodic changes in the external environment and this feature allows a competitive advantage at both the species and individual level. Among the physiological parameters which need accurate adjustment during a 24-h period are fluid, electrolyte, acid–base balance, urine production, and maintenance of blood pressure. These functions are all mediated by the kidneys—organs that are critical for the regulation of blood pressure and the maintenance of body homeostasis. Developing evidence clearly demonstrates a role for the molecular circadian clock in the regulation of several renal ion transporters and channels with implications for circadian control of renal function.

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Authors and Affiliations

  1. Division of Nephrology, Hypertension and Renal Transplantation, Department of Medicine, University of Florida, 1600 SW Archer Road, 100224, Gainesville, FL, 32610, USA

    Kristen Solocinski & Michelle L. Gumz Ph.D.

  2. Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, USA

    Kristen Solocinski & Michelle L. Gumz Ph.D.

  3. Division of Internal Medicine and Chronobiology Unit, Department of Medical Sciences, IRCCS Scientific Institute and Regional General Hospital “Casa Sollievo della Sofferenza”, San Giovanni Rotondo, (FG), Italy

    Gianluigi Mazzoccoli

Authors
  1. Kristen Solocinski
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  2. Gianluigi Mazzoccoli
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  3. Michelle L. Gumz Ph.D.
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Corresponding author

Correspondence to Michelle L. Gumz Ph.D. .

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Editors and Affiliations

  1. University of Florida, Gainesville, Florida, USA

    Michelle L. Gumz

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Solocinski, K., Mazzoccoli, G., Gumz, M.L. (2016). Circadian Regulation of Renal Function. In: Gumz, M. (eds) Circadian Clocks: Role in Health and Disease. Physiology in Health and Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3450-8_6

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