Abstract
The metabolic rate of skeletal muscles during maximal voluntary static contractions can be increased more than 120-fold above the basal rate (5). Phosphocreatine (PCr) in the skeletal muscles serves as an energy (ATP) store at the onset of muscle contraction, the breakdown of which increases the rate of oxidative phosphorylation and stimulates anaerobic glycolysis (1,2). However, little is known about the integration of aerobic and anaerobic pathways of metabolism in skeletal muscles during contraction and ischemia. The aim of this study was to determine the role of PCr in forearm skeletal muscle energetics in two different situations: during voluntary static contractions with different relative forces of maximal voluntary contraction (MVC), and in resting skeletal muscles following forearm arterial occlusion (AO) of different durations.
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References
Bessman, S.P. The creatine-creatine phosphate energy shuttle. Ann. Rev. Biochem. 54: 831–862, 1985.
Hochachka, P.W. Fuels and pathways as designed systems for support of muscle work. J. Exp. Biol. 115: 149–164, 1985
McCann, DJ., P.A. Molé, and J.R. Caton. Phosphocreatine kinetics in humans during exercise and recovery. Med. Sci. Sports Ex. 27: 378–389, 1995.
Piiper, J., P.E. Di Prampero, and P. Cerretelli. Relationship between oxygen consumption and anaerobic metabolism in stimulated gastrocemius muscle of the dog. In: Exercise Bioenergeiics and Gas Exchange, edited by P. Cerretelli and B.J. Whipp. Amsterdam: Elsevier/North Holland, 1980. pp. 35–44.
Skards, J., and A. Paeglitis. The energetic supply of the voluntary static contraction of human skeletal muscle, Izvestia Akademii Nauk Latv. SSR 403: 105–122, 1981 (in Russian).
Skards, J., A. Paeglitis, D. Matisone, and E. Eglitis. The role of sympathetic vasoconstrictors providing aerobic work capacity of skeletal muscle. Sechenov. Physiol. J. USSR 72(9): 1275–1283, 1986 (in Russian).
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© 1996 Springer Science+Business Media New York
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Matisone, D., Skards, J., Paeglitis, A., Dzerve, V. (1996). Phosphocreatine as an Energy Store and Energy Shuttle in Human Skeletal Muscles. In: Steinacker, J.M., Ward, S.A. (eds) The Physiology and Pathophysiology of Exercise Tolerance. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5887-3_11
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DOI: https://doi.org/10.1007/978-1-4615-5887-3_11
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