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Antioxidant Defenses in the Vascular Wall

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Oxidative Stress and Vascular Disease

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 224))

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Abstract

Oxidative stress, defined as a disturbance in the pro-oxidant to anti-oxidant balance in favor of the former (1), may lead to oxidative damage, depending on its extent and duration, and the type of oxidant(s) involved. Within the vascular wall both radicals (i.e., one electron) and nucleophilic (two electron) oxidants are likely produced and contribute to oxidative stress (see Chapter 2). This chapter describes antioxidant defenses in the vascular wall in atherosclerosis.

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  1. Roland Stocker
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  1. Boston University School of Medicine, Boston, MA, USA

    John F. Keaney Jr. M.D. (Associate Professor of Medicine and Pharmacology) (Associate Professor of Medicine and Pharmacology)

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Stocker, R. (2000). Antioxidant Defenses in the Vascular Wall. In: Keaney, J.F. (eds) Oxidative Stress and Vascular Disease. Developments in Cardiovascular Medicine, vol 224. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-4649-8_3

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  • DOI: https://doi.org/10.1007/978-1-4615-4649-8_3

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