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Extracorporeal Therapy for Drug Overdose and Poisoning

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Pediatric Dialysis

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Abstract

Poisoning continues to be a significant cause of morbidity and mortality. The 2008 Annual Report of the American Association of Poison Control Centers (AAPCC) published information on 2,491,049 human exposure cases of poisoning, half of them being children younger than 6 years [1]. Prescription drugs, over the counter medications, illicit drugs, and common household substances can all be responsible for poisoning. As per the 2008 Annual Report, the top four most frequently involved substances in all human exposures were analgesics (13.3%), cosmetics/personal care products (9.0%), household cleaning substances (8.6%), and sedatives/hypnotics/antipsychotics (6.6%). Most (82.8%) poison exposures were unintentional, and suicidal intent was suspected in 8.7% of cases. In 10.6% of exposures (263,942 cases), poisoning resulted due to therapeutic errors such as inadvertent double-dosing, incorrect dosing, wrong medication taken or given, and inadvertent exposure to someone else’s medication.

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Author information

Authors and Affiliations

  1. Department of Pediatrics, Section of Pediatric Nephrology, Children’s Mercy Hospitals and Clinics, Kansas City, MO, USA

    Vimal Chadha MD

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  1. Vimal Chadha MD
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Correspondence to Vimal Chadha MD .

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Editors and Affiliations

  1. Children’s Mercy Hospital and Clinics, Department of Pediatrics, Section of Pediatric Nephrology, School of Medicine, Kansas City, 64108, Missouri, USA

    Bradley A. Warady

  2. Center for Pediatrics, and Adolescent Medicine, Division of Pediatric Nephrology, Im Neuenheimer Feld 150, Heidelberg, 69120, Germany

    Franz Schaefer

  3. Department of Pediatrics, Stanford University School of Medicine, Division of Pediatric Nephrology, Welch Road 770, Palo Alto, 94304, California, USA

    Steven R. Alexander

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Chadha, V. (2012). Extracorporeal Therapy for Drug Overdose and Poisoning. In: Warady, B., Schaefer, F., Alexander, S. (eds) Pediatric Dialysis. Springer, Boston, MA. https://doi.org/10.1007/978-1-4614-0721-8_42

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  • DOI: https://doi.org/10.1007/978-1-4614-0721-8_42

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  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4614-0720-1

  • Online ISBN: 978-1-4614-0721-8

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