Abstract
During early vertebrate development, the embryonic body plan is established by cell proliferation, migration, and differentiation. The mechanisms of patterning are complex and likely include multiple so-called induction events. Recent studies of this aspect of developmental biology have been remakably enhanced by the techniques of molecular biology. Most noteworthy is the molecular identification of inducing factors, which are closely associated with determination of the early embryonic axis. Foremost among these are several cell growth factors, including fibroblast growth factors (FGFS) and transforming growth factor-beta (TGF-β).
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Asashima, M., Uochi, T., Kinoshita, K., Nishihara, R., Ariizumi, T., Fukui, A. (1997). Control of Cell Differentiation and Morphogenesis by Activins During Early Amphibian Development. In: Aono, T., Sugino, H., Vale, W.W. (eds) Inhibin, Activin and Follistatin. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1874-6_20
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DOI: https://doi.org/10.1007/978-1-4612-1874-6_20
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