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Proline and Lysine Metabolism

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Pseudomonas

Abstract

Besides their function as building blocks for proteins, certain amino acids have other important physiological roles. Such is the case of the non-polar imino acid proline and of lysine, a basic amino acid. Proline is accumulated by bacterial cells during osmotic stress as one of the prevalent compatible solutes that act as osmoprotectants21, 39. It is also a precursor in the biosynthesis of pyoluteorin, an antifimgal compound produced by several Pseudomonas fluorescens strains35, 47. Lysine is involved in pathogenicity mechanisms in Pseudomonas syringae, by conjugation of the amino acid with indole acetic acid (IAA). These IAA-lysine conjugates interfere with auxin metabolism in plants infected by P. syringae, leading to alterations in plant development10. Lysine also participates indirectly in survival of bacteria to low pH, a stress situation that triggers lysine decarboxylation to produce cadaverine, which reduces outer membrane permeability42, 43.

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Authors and Affiliations

  1. Department of Plant Biochemistry and Molecular and Cellular Biology, Estación Experimental del Zaidín, CSIC, Spain

    Olga Revelles & Manuel Espinosa-Urgel

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  1. Olga Revelles
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  2. Manuel Espinosa-Urgel
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  1. CSIC, Granada, Spain

    Juan-Luis Ramos

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Revelles, O., Espinosa-Urgel, M. (2004). Proline and Lysine Metabolism. In: Ramos, JL. (eds) Pseudomonas. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-9088-4_10

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  • DOI: https://doi.org/10.1007/978-1-4419-9088-4_10

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-4789-7

  • Online ISBN: 978-1-4419-9088-4

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