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Computational Epitope Mapping

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Infectious Disease Informatics

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Abstract

Despite its unequivocal benefits to humankind, vaccine design and development has always been an inherently laborious and a largely empirical process; the unfortunate lack of a rational basis for vaccinology has hitherto stymied the commercial exploitation of vaccine discovery and also the deployment of vaccination as the principal, global instrument of public health provision. Immunoinformatics offers a plethora of programs and techniques that have the potential to simplify greatly the process of discovering vaccines. These techniques can assist in the identification of immunogenic epitopes that might be overlooked by conventional experimentation.

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Authors and Affiliations

  1. SGDP Centre, Institute of Psychiatry, London, United Kingdom

    Matthew N. Davies & Darren R. Flower

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  1. Matthew N. Davies
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  2. Darren R. Flower
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  1. Sydney Medical School, University of Sydney, Sydney, 2006, Australia

    Vitali Sintchenko

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Davies, M.N., Flower, D.R. (2010). Computational Epitope Mapping. In: Sintchenko, V. (eds) Infectious Disease Informatics. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1327-2_9

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