Abstract
It was shown that Acetobacter xylinum cellulose gel-films can sorb silver and selenium nanoparticles stabilized by N-poly(vinyl-2-pirrolidone). The structure of original cellulose matrix, isolated nanoparticles and cellulose with sorbed nanoparticles was characterized by electron diffraction, electron microscopy, small- and wide-angle x-ray scattering methods, and atomic force microscopy. It was found that in static culture Acetobacter xylinum bacterium (strain VKM B-880) may synthesize high-molecular cellulose with narrow molecular weight distribution and a considerable number of carbon sources. The structures of cellulose microfibrilles and ribbons correspond mainly to polymorphous Iβ modification. We concluded from structural studies that textured cellulose films were formed. The sorption conditions of poly(vinylpyrrolidone)-Se° and poly(vinylpyrrolidone)-Ag° nanoparticles were optimized to obtain a cellulose template that can be used in medical practice.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
W. Czaja, A. Krystynowicz, S. Bielecki, and R. M. Brown Jr., Microbial cellulose–the natural power to heal wounds, Biomaterials 27, 145–151 (2006).
B. A. Paramonov, V. V. Kopeikin, A. A. Tkachenko, and A. K. Khripunov, Perspectives of application of wound coating obtained on the basis of cellulose produced by Acetobacter xylinum, in: Proceedings of the First International Scientific and Practical Conference “Modern Polymer Materials in Medicine and Medical Engineering”, St. Petersburg, 2005, pp. 203–205 [in Russian].
I. V. Gofman, A. L. Buyanov, A. K. Khripunov, L. G. Revelskaya, A. A. Tkachenko, and B. A. Paramonov, Polymer compositions based on Acetobacter xylinum cellulose and synthetic polymers: functional properties and prospect of medical applications, Mater., Technol. Instruments 11(1), 35–41 (2006).
Yu. G. Baklagina, A. K. Khripunov, A. A. Tkachenko, E. I. Suvorova, V. V. Klechkovskaya, L. N. Borovikova, R. Yu. Smyslov, V. K. Nilova, Ya. I. Nazarkina, V. K. Lavrent’ev, S. V. Valueva, A. I. Kipper, and V. V. Kopeikin, Interaction of Se0 nanoparticles stabilized by poly(vinylpyrrolidone) with gel films of Acetobacter xylinum cellulose, Crystallogr. Rep., 51(4), 619–626 (2006).
Yu. G. Baklagina, A. K. Khripunov, A. A. Tkachenko, V. V. Kopeikin, N. A. Matveeva, V. K. Lavrent’ev, V. K. Nilova, T.E. Sukhanova, R. Yu. Smyslov, I. S. Zanaveskina, V. V. Klechkovskaya, and L. A. Feigin, Sorption properties of bacterial cellulose gel films, Russ. J. Appl. Chem. 78(7), 1176–1181 (2005).
V. A. Baraboj, Biological functions, metabolism, and mechanisms of selenium effects, Adv. Curr. Biol., 124(2), 157–168 (2004) [in Russian].
Yu. G. Baklagina, A. K. Khripunov, A. A. Tkachenko, S. V. Gladchenko, V. K. Lavrent’ev, A. Ya. Volkov, V. K. Nilova, V. M. Denisov, T.E. Sukhanova, I. S. Zanaveskina, V. V. Klechkovskaya, and L. A. Feigin, Structural parameters of cellulose produced by Acetobacter xylinum and their variation in the course of drying of gel films, Russ. J. Appl. Chem. 76(6), 989–996 (2003).
V. V. Kopeikin and E. F. Panarin, Water-soluble nanocomposites of zerovalent metallic silver with enhanced antimicrobial activity, Dokl. Chem. 380(4–6), 277–280 (2001).
A. K. Khripunov, A. A. Tkachenko, Yu. G. Baklagina, V. V. Kopeikin, M. A. Katsdze, A. G. Miroshnichenko, and E. F. Panarin, Bacterial cellulose–perspective materials for use in medical practice, in: Proceedings of the Second International Conference “Modern Approaches to the Design of Effective Medical Dressings, Suture Materials, and Polymer Implantants”, Moscow, November 21–22, 1995, p. 71 [in Russian].
D. I. Svergun, Determination of the regularization parameter in indirect-transform methods using perceptual criteria, J. Appl.Cryst. 25, 495–503 (1992).
H.-P. Fink, H. J. Purz, A. Bohn, and J. Kunze, Investigation of the supramolecular structure of never dried bacterial cellulose, Macromol. Symp. 120, 207–217 (1997).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2008 Springer Science + Business Media B.V
About this paper
Cite this paper
Klechkovskaya, V. et al. (2008). Network Model of Acetobacter Xylinum Cellulose Intercalated by Drug Nanoparticles. In: Giersig, M., Khomutov, G.B. (eds) Nanomaterials for Application in Medicine and Biology. NATO Science for Peace and Security Series. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6829-4_14
Download citation
DOI: https://doi.org/10.1007/978-1-4020-6829-4_14
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-6827-0
Online ISBN: 978-1-4020-6829-4
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)