Abstract
The nucleoskeleton (NSK) is the dynamic nuclear network that provides support for nuclear organization and functioning. It is composed of numerous interacting structural proteins that provide a dynamic platform for the multimeric nuclear complexes involved in the regulation of replication, transcription/splicing, chromatin remodelling, nuclear transport, signalling, formation of structural elements, etc. Its protein composition is complex. Its main components are the lamins and the lamin-associated proteins (LAPs) that form a multimeric complex or lamina; the long expandable proteins of the endoskeleton such as EAST, megator, skeletor, chromator and nuance; and actin and its associated proteins; while the nucleolar domain has its own organization and composition . This chapter focuses on the organization, composition and roles of the nucleoskeleton and summarizes the data on the organization and specific protein composition of the plant nucleoskeleton.
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Acknowledgements
I thank my former and present students who collaborated in collection of the data concerning the onion nucleoskeleton: A. Mínguez, W. Yu, R. Samaniego, F. Novillo, H. Li, J.R. Cruz and C. Pérez-Munive, and M. Carnota for expert technical assistance. This work was supported by Spanish DGI project BFU 2007–60142/BFI.
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