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Carboxymethyl Chitosan Derivatives in Blood Clotting

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Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications

Part of the book series: Advances in Polymer Science ((POLYMER,volume 292))

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Abstract

Hemorrhage is one of the major challenges in healthcare area. Many hemostats are commercially available, but their application is limited due to high cost, non-biocompatible and immunogenic properties. Chitosan and its derivatives have been extensively used as a hemostatic material to stop bleeding. The amine and hydroxyl groups of chitosan are modified into different derivatives, for exhibiting better solubility, hemostatic properties, biocompatibility, moisture absorption, film-forming, and antibacterial activities. One such derivative is carboxymethyl chitosan and it has been widely studied for hemostatic and other biomedical applications. In this book chapter, we are overviewing the different forms of carboxymethyl chitosan derivatives such as hydrogel, sponges, cryogel, membranes and microspheres which were studied for hemostatic applications.

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Author notes

  1. C. Arthi and P. M. Nazreen contributed equally to this work.

Authors and Affiliations

  1. Polymeric Biomaterials Lab, School of Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi, India

    C. Arthi, P. M. Nazreen, M. Nivedhitha Sundaram & R. Jayakumar

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  1. C. Arthi
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  2. P. M. Nazreen
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  3. M. Nivedhitha Sundaram
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  4. R. Jayakumar
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Correspondence to R. Jayakumar .

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Editors and Affiliations

  1. Centre for Nanosciences and Molecular Medicine, Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham (University), Kochi, Kerala, India

    R. Jayakumar

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Arthi, C., Nazreen, P.M., Nivedhitha Sundaram, M., Jayakumar, R. (2023). Carboxymethyl Chitosan Derivatives in Blood Clotting. In: Jayakumar, R. (eds) Multifaceted Carboxymethyl Chitosan Derivatives: Properties and Biomedical Applications. Advances in Polymer Science, vol 292. Springer, Cham. https://doi.org/10.1007/12_2023_161

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