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Image-Guided Tumor Ablation: Basic Science

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Tumor Ablation

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Abstract

Minimally invasive strategies in image-guided tumor ablation are gaining increasing attention as viable therapeutic options for focal primary and secondary hepatic malignancies (1–3). Although liver transplantation continues to be the standard for cure of hepatocellular carcinoma (HCC), there remains a clear need for treatment alternatives in the large population of HCC patients unable to qualify for liver transplantation surgery (4). For hepatic metastases, while conventional surgical resection has demonstrated acceptable rates of success (5) in carefully selected patient populations, several classes of minimally invasive, image-guided therapeutic strategies are being vigorously explored as practical alternatives (2,3). Possible advantages of minimally invasive therapies compared to surgical resection include the anticipated reduction in morbidity and mortality, lower cost, the ability to perform procedures on outpatients, and the potential application in a wider spectrum of patients, including nonsurgical candidates.

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Authors and Affiliations

  1. Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, USA

    Muneeb Ahmed MD (Research Assistant in Radiology)

  2. Minimally Invasive Tumor Therapy Laboratory, Department of Radiology and Abdominal Imaging, Beth Israel Deaconess Medical Center, Boston, MA, USA

    S. Nahum Goldberg MD (Associate Professor of Radiology, Harvard Medical School, Director, Abdominal Intervention and Tumor Ablation, Director)

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  1. Muneeb Ahmed MD
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  2. S. Nahum Goldberg MD
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Editors and Affiliations

  1. Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, 02115, USA

    Eric vanSonnenberg MD (Chief of Radiology, Interventional Radiologist) (Chief of Radiology, Interventional Radiologist)

  2. Brigham and Women’s Hospital Children’s Hospital, Boston, MA, 02115, USA

    Eric vanSonnenberg MD (Chief of Radiology, Interventional Radiologist) (Chief of Radiology, Interventional Radiologist)

  3. Boston, MA, 02115, USA

    William N. McMullen (Interventional Oncology Consultant) (Interventional Oncology Consultant)

  4. Department of Radiology, Ospedale Civile Busto Arsizio, 21052, Busto Arsizio, Italy

    Luigi Solbiati MD (Chairman) (Chairman)

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Ahmed, M., Goldberg, S.N. (2005). Image-Guided Tumor Ablation: Basic Science. In: vanSonnenberg, E., McMullen, W.N., Solbiati, L., Livraghi, T., Müeller, P.R., Silverman, S.G. (eds) Tumor Ablation. Springer, New York, NY. https://doi.org/10.1007/0-387-28674-8_3

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