Summary
Hemorrhage in the obstetric cases occurs unexpectedly and potentially causes serious maternal and fetal morbidity and mortality. Various aspects of antepartum hemorrhage, current obstetric guidelines including nonsurgical and surgical interventions during obstetric hemorrhage, and special anesthetic considerations have been reviewed. Excellent critical care management minimizes postoperative morbidity and mortality after obstetric hemorrhage. A well-equipped labor and delivery operative suite staffed by expert obstetric, anesthesia, neonatal, and nursing teams leads to successful outcome for the mother and baby in obstetric hemorrhagic emergencies.
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References
Baker RJ. Hemorrhage in obstetrics. Obstet Gynecol Annu 1977;6:295.
American College of Obstetricians and Gynecologists. Hemorrhagic Shock, vol 1. ACOG Tech Bull 1984;82.
Kaunitz AM, Hughes JM, Grimes DA, et al. Causes of maternal mortality in the United States. Obstet Gynecol 1985;65(5):605–612.
Chichakli LO, Atrash HK, MacKay AP, et al. Pregnancy-related mortality in the United States due to hemorrhage: 1979–1992. Obstet Gynecol 1999;94(5 pt 1):721–725.
Atrash HK, Koonin LM, Lawson HW, et al. Maternal mortality in the United States, 1979–1986. Obstet Gynecol 1990;76(6):1055–1060.
Berg CJ, Atrash HK, Koonin LM, Tucker M. Pregnancy-related mortality in the United States, 1987–1990. Obstet Gynecol 1996;88(2): 161–167.
Cheek TG, Gutsche BB. Maternal physiologic alterations during pregnancy. In: Shnider SM, Levinson G (eds) Anesthesia for Obstetrics. Baltimore: Williams & Wilkins, 1993.
Brock-Utne JG, Downing JW, Seedat F. Laryngeal oedema associated with pre-eclamptic toxaemia. Anaesthesia 1977;32(6):556–558.
Seager SJ, Macdonald R. Laryngeal oedema and pre-eclampsia. Anaesthesia 1980;35(4):360–362.
Hein HA. Cardiorespiratory arrest with laryngeal oedema in pregnancy-induced hypertension. Can Anaesth Soc J 1984;31(2):210–212.
Brimacombe J. Acute pharyngolaryngeal oedema and pre-eclamptic toxaemia. Anaesth Intensive Care 1992;20(1):97–98.
Rocke DA, Scoones GP. Rapidly progressive laryngeal oedema associated with pregnancy-aggravated hypertension. Anaesthesia 1992;47(2): 141–143.
Jouppila R, Jouppila P, Hollmen A. Laryngeal oedema as an obstetric anaesthesia complication: case reports. Acta Anaesthesiol Scand 1980; 24(2):97–98.
Pilkington S, Carli F, Dakin MJ, et al. Increase in Mallampati score during pregnancy. Br J Anaesth 1995;74(6):638–642.
Farcon EL, Kim MH, Marx GF. Changing Mallampati score during labour. Can J Anaesth 1994;41(1):50–51.
Bhavani-Shankar K, Lynch EP, Datta S. Airway changes during Cesarean hysterectomy. Can J Anaesth 2000;47(4):338–341.
Suresh MS. Difficult airway in the parturient. In: Fleisher LA, Prough DS (eds) Problems in Anesthesia. Airway Management. Hagerstown, MD: Lippincott/Williams & Wilkins, 2001:88–99.
Prowse CM. Respiratory and acid-base changes during pregnancy. Anesthesiology 1965;26(4):381–392.
Andersen GJ. The maternal oxygen tension and acid-base status during pregnancy. J Obstet Gynaecol Br Commonw 1969;76:16–19.
Lucius H, Gahlenbeck H, Kleine HO, et al. Respiratory functions, buffer system, and electrolyte concentrations of blood during human pregnancy. Respir Physiol 1970;9(3):311–317.
Lim VS, Katz AI, Lindheimer MD. Acid-base regulation in pregnancy. Am J Physiol 1976;231(6):1764–1769.
Templeton A, Kelman GR. Maternal blood-gases, PAO2−PaO2): Hysiological shunt and VD/VT in normal pregnancy. Br J Anaesth 1976; 48(10):1001–1004.
Leontic EA. Respiratory disease in pregnancy. Med Clin N Am 1977; 61(1):111–128.
Kirshon B, Cotton DB. Invasive hemodynamic monitoring in the obstetric patient. Clin Obstet Gynecol 1987;30(3):579–590.
Robson SC, Hunter S, Boys RJ, Dunlop W. Serial study of factors influencing changes in cardiac output during human pregnancy. Am J Physiol 1989;256(4 pt 2):H1060–H1065.
Clark SL, Cotton DB, Lee W, et al. Central hemodynamic assessment of normal term pregnancy. Am J Obstet Gynecol 1989;161(6 pt 1): 1439–1442.
Gant NFWR. Measurement of uteroplacental blood flow in the human. In: Rosenfeld CR (ed) The Uterine Circulation. Ithaca: Perinatology Press, 1989:53–73.
Chesley LC. The effect of posture on renal function in late pregnancy. Am J Obstet Gynecol 1964;89(6):754–759.
Wilson M, Morganti AA, Zervoudakis I, et al. Blood pressure, the reninaldosterone system and sex steroids throughout normal pregnancy. Am J Med 1980;68(1):97–104.
Duvekot JJ, Cheriex EC, Pieters FA, et al. Early pregnancy changes in hemodynamics and volume homeostasis are consecutive adjustments triggered by a primary fall in systemic vascular tone. Am J Obstet Gynecol 1993;169(6):1382–1392.
Lund CJ. Blood volume during pregnancy: significance of plasma and red cell volumes. Am J Obstet Gynecol 1967;98:393–403.
Gatti L, Tenconi PM, Guarneri D, et al. Hemostatic parameters and platelet activation by flow-cytometry in normal pregnancy: a longitudinal study. Int J Clin Lab Res 1994;24(4):217–219.
Astedt B. Significance of placenta in depression of fibrinolytic activity during pregnancy. J Obstet Gynaecol Br Commonw 1972;79(3):205–206.
Chandler WL. The thromboelastograph and the thromboelastograph technique. Semin Thromb Hemost 1995;21:1–6.
Sharma SK. Thromboelastographic changes in healthy parturients and postpartum women. Anesth Analg 1997;85:94–98.
Gruenwald P, Levin H, Yousem H. Abruption and premature separation of the placenta. The clinical and the pathologic entity. Am J Obstet Gynecol 1968;102(4):604–610.
Hirris BA. Marginal placental bleeding. Anatomical and pathological considerations. Am J Obstet Gynecol 1952;64(1):53–61.
Harris BA Jr, Gore H, Flowers CE Jr. Peripheral placental separation: a possible relationship to premature labor. Obstet Gynecol 1985;66(6): 774–778.
Nyberg DA, Cyr DR, Mack LA, et al. Sonographic spectrum of placental abruption. AJR Am J Roentgenol 1987;148(1):161–164.
Pritchard JA, Mason R, Corley M, Pritchard S. Genesis of severe placental abruption. Am J Obstet Gynecol 1970;108(1):22–27.
Ananth CV, Berkowitz GS, Savitz DA, Lapinski RH. Placental abruption and adverse perinatal outcomes. JAMA 1999;282(17):1646–1651.
Paterson ME. The aetiology and outcome of abruptio placentae. Acta Obstet Gynecol Scand 1979;58(1):31–35.
Pritchard JA, Brekken AL. Clinical and laboratory studies on severe abruptio placentae. Am J Obstet Gynecol 1967;97(5):681–700.
Hurd WW, Miodovnik M, Hertzberg V, Lavin JP. Selective management of abruptio placentae: a prospective study. Obstet Gynecol 1983;61(4):467–473.
Spirt BA, Kagan EH, Rozanski RM. Abruptio placenta: sonographic and pathologic correlation. AJR Am J Roentgenol 1979;133(5):877–881.
Jaffe MH, Schoen WC, Silver TM, et al. Sonography of abruptio placentae. AJR Am J Roentgenol 1981;137(5):1049–1054.
McGahan JP, Phillips HE, Reid MH, Oi RH. Sonographic spectrum of retroplacental hemorrhage. Radiology 1982;142(2):481–485.
Abdella TN, Sibai BM, Hays JM Jr, Anderson GD. Relationship of hypertensive disease to abruptio placentae. Obstet Gynecol 1984;63(3): 365–370.
Hibbard BM, Jeffcoate TN. Abruptio placentae. Obstet Gynecol 1966; 27(2):155–167.
Green JR. Placental abnormalities: placenta previa and abruptio placentae. In: Creasy RKR (ed) Maternal Fetal Medicine: Principles and Practice. Philadelph: Saunders, 1994:592–612.
Muldoon MJ. The use of central venous pressure monitoring in abruptio placentae. J Obstet Gynaecol Br Commonw 1969;76:225.
Shoemaker WC. Resuscitation of the critically ill patient. Use of branched-chain decision trees to improve outcome. Emerg Med Clin N Am 1986;4(4):655–694.
Czer LS, Shoemaker WC. Optimal hematocrit value in critically ill postoperative patients. Surg Gynecol Obstet 1978;147(3):363–368.
Oats JN, Vasey DP, Waldron BA. Effects of ketamine on the pregnant uterus. Br J Anaesth 1979;51(12):1163–1166.
Suresh MS. Comparison of etomidate with thiopental for induction of anesthesia at cesarean section. Anesthesiology 1986;65(3A):A400.
Andrews WW. Effect of type of anesthesia on blood loss at elective repeat cesarean section. Am J Perinatology 1992;9(3):197–200.
Belfort MA, Rokey R, Saade GR, Moise KJ Jr. Rapid echocardiographic assessment of left and right heart hemodynamics in critically ill obstetric patients. Am J Obstet Gynecol 1994;171(4):884–892.
Murphy MB, Murray C, Shorten GD. Fenoldopam—a selective peripheral dopamine-receptor agonist for the treatment of severe hypertension. N Engl J Med 2001;345(21):1548–1557.
Halpenny M, Markos F, Snow HM, et al. Effects of prophylactic fenoldopam infusion on renal blood flow and renal tubular function during acute hypovolemia in anesthetized dogs. Crit Care Med 2001;29(4): 855–860.
Poinsot O, Romand JA, Favre H, Suter PM. Fenoldopam improves renal hemodynamics impaired by positive end-expiratory pressure. Anesthesiology 1993;79(4):680–684.
Mathur VS, Swan SK, Lambrecht LJ, et al. The effects of fenoldopam, a selective dopamine receptor agonist, on systemic and renal hemodynamics in normotensive subjects. Crit Care Med 1999;27(9):1832–1837.
Douglas RG, Buckman MI, MacDonald PF. Premature separation of the normally implanted placenta. J Obstet Gynaecol Br Emp 1955;62:710.
Basu HK. Fibrinolysis and abruptio placentae. Br J Obstet Gynaecol 1969;76:481.
Sher G. Pathogenesis and management of uterine inertia complicating abruptio placentae with consumption coagulopathy. Am J Obstet Gynecol 1977;129(2):164–170.
Clark SL, Cotton DB, Hankins G, Phelan JP. Critical Care Obstetrics, 3rd edn. Oxford: Blackwell Publishing 1997.
Collins JA. Recent developments in the area of massive transfusion. World J Surg 1987;11(1):75–81.
Consensus Conference. Platelet transfusion therapy. JAMA 1987;257: 1777–1780.
Sharma SK. Assessment of parturients with TEG during massive hemorrhage. In: Abstracts, Society for Obstetric Anesthesiology and Perinatology 27th Annual Meeting, 1995;132.
McNicol PL, Liu G, Harley ID, et al. Blood loss and transfusion requirements in liver transplantation: experience with the first 75 cases. Anaesth Intensive Care 1994;22(6):666–671.
Wilson RJ. Bleeding during late pregnancy. In: Wilson RJ (ed) St. Louis: Mosby, 1983.
Clark SL, Koonings PP, Phelan JP. Placenta previa/accreta and prior cesarean section. Obstet Gynecol 1985;66(1):89–92.
Silver R, Depp R, Sabbagha RE, et al. Placenta previa: aggressive expectant management. Am J Obstet Gynecol 1984;150(1):15–22.
Cotton DB, Read JA, Paul RH, Quilligan EJ. The conservative aggressive management of placenta previa. Am J Obstet Gynecol 1980;137(6): 687–695.
Wexler P, Gottesfeld KR. Second trimester placenta previa. An apparently normal placentation. Obstet Gynecol 1977;50(6):706–709.
Wexler P, Gottesfeld KR. Early diagnosis of placenta previa. Obstet Gynecol 1979;54(2):231–234.
Farine D, Peisner DB, Timor-Tritsch IE. Placenta previa—is the traditional diagnostic approach satisfactory? J Clin Ultrasound 1990;18(4): 328–330.
Powell MC, Buckley J, Price H, et al. Magnetic resonance imaging and placenta previa. Am J Obstet Gynecol 1986;154(3):565–569.
Naeye RL, Harkness WL, Utts J. Abruptio placentae and perinatal death: a prospective study. Am J Obstet Gynecol 1977;128(7):740–746.
Brenner WE, Edelman DA, Hendricks CH. Characteristics of patients with placenta previa and results of “expectant management”. Am J Obstet Gynecol 1978;132(2):180–191.
Droste S, Keil K. Expectant management of placenta previa: cost-benefit analysis of outpatient treatment. Am J Obstet Gynecol 1994; 170(5 pt 1):1254–1257.
Mouer JR. Placenta previa: antepartum conservative management, inpatient versus outpatient. Am J Obstet Gynecol 1994;170(6):1683–1685.
Wing DA, Paul RH, Millar LK. Management of the symptomatic placenta previa: a randomized, controlled trial of inpatient versus outpatient expectant management. Am J Obstet Gynecol 1996;175(4 pt 1): 806–811.
Abboud TK. Anesthesia for placenta previa at Women’s Hospital: 3 year survey. In: Abstracts, 25th Annual Meeting, 1993;19.
Chestnut DH, Thompson CS, McLaughlin GL, Weiner CP. Does the intravenous infusion of ritodrine or magnesium sulfate alter the hemodynamic response to hemorrhage in gravid ewes? Am J Obstet Gynecol 1988;159(6):1467–1473.
Sipes SL, Chestnut DH, Vincent RD Jr, et al. Which vasopressor should be used to treat hypotension during magnesium sulfate infusion and epidural anesthesia? Anesthesiology 1992;77(1):101–108.
Sherman SJ, Greenspoon JS, Nelson JM, Paul RH. Identifying the obstetric patient at high risk of multiple-unit blood transfusions. J Reprod Med 1992;37(7):649–652.
McVay PA, Hoag RW, Hoag MS, Toy PT. Safety and use of autologous blood donation during the third trimester of pregnancy. Am J Obstet Gynecol 1989;160(6):1479–1486.
Consensus conference. Perioperative red blood cell transfusion. JAMA 1988;260(18):2700–2703.
Practice Guidelines for blood component therapy. A report by the American Society of Anesthesiologists Task Force on Blood Component Therapy. Anesthesiology 1996;84(3):732–747.
Graber SE, Krantz SB. Erythropoietin and the control of red cell production. Annu Rev Med 1978;29:51–66.
Egrie JC. Characterization and biological effects of human recombinant erythropoietin. Immunobiology 1986;172:213–224.
Eschbach JW, Egrie JC, Downing MR, et al. Correction of the anemia of end-stage renal disease with recombinant human erythropoietin. Results of a combined phase I and II clinical trial. N Engl J Med 1987; 316(2):73–78.
Eschbach JW, Abdulhadi MH, Browne JK, et al. Recombinant human erythropoietin in anemic patients with end-stage renal disease. Results of a phase III multicenter clinical trial. Ann Intern Med 1989;111(12): 992–1000.
Rutherford CJ, Schneider TJ, Dempsey H, et al. Efficacy of different dosing regimens for recombinant human erythropoietin in a simulated perisurgical setting: the importance of iron availability in optimizing response. Am J Med 1994;96(2):139–145.
Abraham PA, Halstenson CE, Macres MM, et al. Epoietin enhances erythropoiesis in normal men undergoing repeated phlebotomies. Clin Pharmacol Ther 1992;52:205.
Fishbane S, Maesaka JK. Iron management in end-stage renal disease. Am J Kidney Dis 1997;29(3):319–333.
Sowade O, Warnke H, Scigalla P, et al. Avoidance of allogeneic blood transfusions by treatment with epoetin beta (recombinant human erythropoietin) in patients undergoing open-heart surgery. Blood 1997;89(2): 411–418.
Goldberg MA, McCutchen JW, Jove M, et al. A safety and efficacy comparison study of two dosing regimens of epoetin alfa in patients undergoing major orthopedic surgery. Am J Orthop 1996;25(8):544–552.
Dodril FD. The use of the heart-lung apparatus in human cardiac surgery. J Thorac Cardiovasc Surg 1957;33:60–74.
Helm RE, Klemperer J D, Rosengart TK, et al. Intraoperative autolgous blood donation preserves red cell mass but does not decrease post-operative bleeding. Ann Thorac Surg 1996;62(5):1431–1441.
Kochamba GS, Pfeffer TA, Sintek CF, Khonsari S. Intraoperative autotransfusion reduces blood loss after cardiopulmonary bypass. Ann Thorac Surg 1996;61(3):900–903.
Stehling L, Zauder HL. Acute normovolemic hemodilution. Transfusion 1991;31(9):857–868.
Stehling L. Alternatives to allogeneic transfusion. In: Petz LD (ed) Clinical Practice of Transfusion Medicine. New York: Churchill Livingstone, 1996:539–561.
Stehling L, Zauder HL. Controversies in transfusion medicine. Perioperative hemodilution: pro. Transfusion 1994;34(3):265–268.
Estella NM. Normovolemic hemodilution before cesarean hysterectomy for placenta percreta. Obstet Gynecol 1997;89:1–2.
Grange CS, Douglas MJ, Adams TJ, Wadsworth LD. The use of acute hemodilution in parturients undergoing cesarean section. Am J Obstet Gynecol 1998;178(1 pt 1):156–160.
Gross JB. Estimating allowable blood loss: corrected for dilution. Anesthesiology 1983;58(3):277–280.
Monk TG, Goodnough LT, Birkmeyer JD, et al. Acute normovolemic hemodilution is a cost-effective alternative to preoperative autologous blood donation by patients undergoing radical retropubic prostatectomy. Transfusion 1995;35(7):559–565.
Monk TG, Goodnough LT. Blood conservation strategies to minimize allogeneic blood use in urologic surgery. Am J Surg 1995;170(6A suppl): 69S–73S.
Baker BW. Blood Conservation, obstetrics, and Jehovah’s Witnesses. Anesthesiol Clin N Am 1998;16(2):375–384.
Messmer K, Kreimeier U, Intaglietta M. Present state of intentional hemodilution. Eur Surg Res 1986;18(3–4):254–263.
Goodnough LT, Brecher ME, Kanter MH, AuBuchon JP. Transfusion medicine. First of two parts—blood transfusion. N Engl J Med 1999; 340(6):438–447.
Stramer SL, Caglioti S, Strong DM. NAT of the United States and Canadian blood supply. Transfusion 2000;40(10):1165–1168.
Rainaldi MP, Tazzari PL, Scagliarini G, et al. Blood salvage during caesarean section. Br J Anaesth 1998;80(2):195–198.
Jackson SH, Lonser RE. Safety and effectiveness of intracesarean blood salvage. Transfusion 1993;33(2):181.
Rebarber A, Lonser R, Jackson S, et al. The safety of intraoperative autologous blood collection and autotransfusion during cesarean section. Am J Obstet Gynecol 1998;179(3 pt 1):715–720.
Potter PS, Waters JH, Burger GA, Mraovic B. Application of cell-salvage during cesarean section. Anesthesiology 1999;90(2):619–621.
National Heart La. Transfusion alert: use of autologous blood. National Heart, Lung, and Blood Institute Expert Panel on the Use of Autologous Blood. Transfusion 1995;35(8):703–711.
Bernstein HH, Rosenblatt MA, Gettes M, Lockwood C. The ability of the Haemonetics 4 Cell Saver System to remove tissue factor from blood contaminated with amniotic fluid. Anesth Analg 1997;85(4):831–833.
Fong J, Gurewitsch ED, Kump L, Klein R. Clearance of fetal products and subsequent immunoreactivity of blood salvaged at cesarean delivery. Obstet Gynecol 1999;93(6):968–972.
Cattling SJ. Cell salvage in obstetrics: an evaluation of the ability of cell salvage combined with leucocyte depletion filtration to remove amniotic fluid from operative blood loss at cesarean section. Int J Obstet Anesth 1999;8:79–84.
Waters JH, Biscotti C, Potter PS, Phillipson E. Amniotic fluid removal during cell salvage in the cesarean section patient. Anesthesiology 2000;92(6):1531–1536.
Durand FD. Rheologic and cytologic study of autologous blood collected with cell savers during cesarean. Rev Fr Transfusion Hemobiol 1989;32:179–191.
Weiskopf RB. Erythrocyte salvage during cesarean section. Anesthesiology 2000;92(6):1519–1522.
Nightingale SD. Summary of Meeting of the DHSS Advisory Committee on Blood Safety and Availability, 29–30 May 1999. Washington, DC: U.S. Department of Health and Human Services, Office of the Secretary.
Cunningham FG, MacDonald PC, Gant NF. Diseases and abnormalities of the fetal membranes. In: Cunningham FG and Williams SW, (eds) Williams Obstetrics, 20th edn. Stamford, CT: Appleton & Lange, 1997:674.
Antoine C, Young BK, Silverman F. Sinusoidal fetal heart rate pattern with vasa previa in twin pregnancy. Obstet Gynecol 1982;27:295.
Benirschke K, Kaufmann P. The Pathology of the Human Placenta. New York: Springer-Verlag, 1995.
Lynch C, Coker A, Lawal AH, et al. The B-Lynch surgical technique for the control of massive postpartum haemorrhage: an alternative to hysterectomy? Five cases reported. Br J Obstet Gynaecol 1997;104(3): 372–375.
Ferguson JE, Bourgeois FJ, Underwood PB. B-Lynch suture for postpartum hemorrhage. Obstet Gynecol 2000;95(6 pt 2):1020–1022.
Clark SL. Placenta previa and abruptio placentae. In: Creasy RK, Resnik R (eds) Maternal-Fetal Medicine. Philadelphia: Saunders, 1999:620.
Zaki ZM, Bahar AM, Ali ME, et al. Risk factors and morbidity in patients with placenta previa accreta compared to placenta previa non-accreta. Acta Obstet Gynecol Scand 1998;77(4):391–394.
Kay HH, Spritzer CE. Preliminary experience with magnetic resonance imaging in patients with third-trimester bleeding. Obstet Gynecol 1991;78(3 pt 1):424–429.
Levine D, Barnes PD, Edelman RR. Obstetric MR imaging. Radiology 1999;211(3):609–617.
Ha TP, Li KC. Placenta accreta: MRI antenatal diagnosis and surgical correlation. J Magn Reson Imaging 1998;8(3):748–750.
Hudon L, Belfort MA, Broome DR. Diagnosis and management of placenta percreta: a review. Obstet Gynecol Surv 1998;53(8):509–517.
Maldjian C, Adam R, Pelosi M, et al. MRI appearance of placenta percreta and placenta accreta. Magn Reson Imaging 1999;17(7):965–971.
Ito T, Katagiri C, Ikeno S, et al. Placenta previa increta penetrating the entire thickness of the uterine myometrium: ultrasonographic and magnetic resonance imaging findings. J Obstet Gynaecol Res 1999;25(5): 303–307.
Chou MM, Ho ES, Lee YH. Prenatal diagnosis of placenta previa accreta by transabdominal color Doppler ultrasound. Ultrasound Obstet Gynecol 2000;15(1):28–35.
Kidney DD, Nguyen AM, Ahdoot D, et al. Prophylactic perioperative hypogastric artery balloon occlusion in abnormal placentation. AJR Am J Roentgenol 2001;176(6):1521–1524.
Dubois J, Garel L, Grignon A, et al. Placenta percreta: balloon occlusion and embolization of the internal iliac arteries to reduce intraoperative blood losses. Am J Obstet Gynecol 1997;176(3):723–726.
Goldberg AB, Greenberg MB, Darney PD. Misoprostol and pregnancy. N Engl J Med 2001;344(1):38–47.
Bamigboye AA, Hofmeyr GJ, Merrell DA. Rectal misoprostol in the prevention of postpartum hemorrhage: a placebo-controlled trial. Am J Obstet Gynecol 1998;179(4):1043–1046.
Hofmeyr GJ, Nikodem VC, de Jager M, Gelbart BR. A randomised placebo controlled trial of oral misoprostol in the third stage of labour. Br J Obstet Gynaecol 1998;105(9):971–975.
Surbek DV, Fehr PM, Hosli I, Holzgreve W. Oral misoprostol for third stage of labor: a randomized placebo-controlled trial. Obstet Gynecol 1999;94(2):255–258.
Gulmezoglu AM, Villar J, Ngoc NT, et al. WHO multicentre randomised trial of misoprostol in the management of the third stage of labour. Lancet 2001;358(9283):689–695.
Chestnut DH. Obstetric Anesthesia. Principles and Practice, 2nd edn. St. Louis: Mosby, 1999.
Chestnut DH, Dewan DM, Redick LF, et al. Anesthetic management for obstetric hysterectomy: a multi-institutional study. Anesthesiology 1989;70(4):607–610.
Sprung J, Cheng EY, Patel S. When to remove an epidural catheter in a parturient with disseminated intravascular coagulation. Reg Anesth 1992;17(6):351–354.
Abbi M, Misra R. Rupture of uterus in a primigravida prior to onset of labor. Int J Fertil Womens Med 1997;42(6):418–420.
Milon D, Chevrant-Breton O, Tekam S, et al. Rupture of the uterus during labor without apparent cause. Eur J Obstet Gynecol Reprod Biol 1983;15(1):1–4.
Nel JT. An unusual case of uterine rupture. A case report. S Afr Med J 1984;65(2):60–61.
Langton J, Fishwick K, Kumar B, Nwosu EC. Spontaneous rupture of an unscarred gravid uterus at 32 weeks gestation. Hum Reprod 1997; 12(9):2066–2067.
Fischer RL. Spontaneous rupture of an unscarred uterus in a primigravid woman. Am J Obstet Gynecol 1996;175(2):504–505.
American College of Obstetricians and Gynecologists. Vaginal birth after previous cesarean delivery. In: The American College of Obstetricians and Gynecologists (ed) 2001 Compendium of Selected Publications. Washington, DC: The American College of Obstetricians and Gynecologists, 1999:1106–1112.
Holt VL, Mueller BA. Attempt and success rates for vaginal birth after caesarean section in relation to complications of the previous pregnancy. Paediatr Perinat Epidemiol 1997;11 Suppl 1:63–72.
Hoskins IA, Gomez JL. Correlation between maximum cervical dilatation at cesarean delivery and subsequent vaginal birth after cesarean delivery. Obstet Gynecol 1997;89(4):591–593.
Lydon-Rochelle M, Holt VL, Easterling TR, Martin DP. Risk of uterine rupture during labor among women with a prior cesarean delivery. N Engl J Med 2001;345(1):3–8.
Zelop CM, Shipp TD, Repke JT, et al. Uterine rupture during induced or augmented labor in gravid women with one prior cesarean delivery. Am J Obstet Gynecol 1999;181(4):882–886.
Crosby WMCJ. Safety of lapbelt restraint for pregnant victims of automobile collisions. N Engl J Med 1971;284:6326–6329.
Rothenberger D, Quattlebaum FW, Perry JF Jr, et al. Blunt maternal trauma: a review of 103 cases. J Trauma 1978;18(3):173–179.
O’Keeffe DF. When the accident victim is pregnant. Contemp Ob Gyn 1985;148–163.
Nelson DM, Stempel LE, Zuspan FP. Association of prolonged, preterm premature rupture of the membranes and abruptio placentae. J Reprod Med 1986;31(4):249–253.
Chasnoff IJ, Burns KA, Burns WJ. Cocaine use in pregnancy: perinatal morbidity and mortality. Neurotoxicol Teratol 1987;9(4):291–293.
Rice JP, Kay HH, Mahony BS. The clinical significance of uterine leiomyomas in pregnancy. Am J Obstet Gynecol 1989;160(5 pt 1): 1212–1216.
Glueck CJ, Kupferminc MJ, Fontaine RN, et al. Genetic hypofibrinolysis in complicated pregnancies. Obstet Gynecol 2001;97(1):44–48.
Kupferminc MJ, Eldor A, Steinman N, et al. Increased frequency of genetic thrombophilia in women with complications of pregnancy. N Engl J Med 1999;340(1):9–13.
van der Molen EF, Arends GE, Nelen WL, et al. A common mutation in the 5,10-methylenetetrahydrofolate reductase gene as a new risk factor for placental vasculopathy. Am J Obstet Gynecol 2000;182(5): 1258–1263.
Hibbard LT. Placenta previa. In: Sciarra JJ, editor. Gynecology and Obstetrics. New York: Harper & Row, 1981.
Iyasu S, Saftlas A, Rowley D. The epidemiology of placenta previa in the United States, 1979 though 1987. Am J Obstet Gynecol 1993;168: 1424.
Ananth CV, Wilcox A, Savitz DA. Effect of maternal age and parity on the risk of uteroplacental bleeding disorders in pregnancy. Obstet Gynecol 1996;88:511.
Kelly JV IL. Placenta Previa. In: Iffy L KH, editor. Principles and Practice of Obstetrics and Perinatology. New York: John Wiley & Sons, 1981.
To WW, Leung WC. Placenta previa and previous cesarean section. Int J Gynaecol Obstet 1995;51(1):25–31.
Clark SL, Koonings PP, Phelan JP. Placenta previa/accreta and prior cesarean section. Obstet Gynecol 1985;66(1):89–92.
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Wali, A., Suresh, M.S., Gregg, A.R. (2004). Antepartum Hemorrhage. In: Datta, S., Hepner, D.L. (eds) Anesthetic and Obstetric Management of High-Risk Pregnancy. Springer, New York, NY. https://doi.org/10.1007/0-387-21572-7_8
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DOI: https://doi.org/10.1007/0-387-21572-7_8
Publisher Name: Springer, New York, NY
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