Abstract
The deformation and behaviour of red blood cells (RBC) were studied in vivo in man with the aid of a skin-tube chamber technique enabling light microscopic observation of the microcirculation at high resolution.
Evidence is presented indicating that RBC deformations in the living microcirculation may be regarded as distortions of the basic biconcave disc shape.
Rouleaux and diapedesis phenomena are discussed and the integrity of the RBC in relation to other blood cells and to the endothelium is emphasized.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Brånemark, P.-I.: Intravascular anatomy of blood cells in man. S. Karger, Basel/New York, 1971
Brånemark, P.-I., Bagge, U., Attefors, R., Stefek, V.: A high resolution light microscope with multirecording capacity for cytorheological studies in vivo in man and animals and in vitro. To be published
Brånemark, P.-I., Langer, L., Fagerberg, S.-E., Breine, U.: Studies in rheology of human diabetes mellitus. Diabetologia7, 107, 1971
Brånemark, P.-I., Lindström, J.: Shape of circulating blood corpuscles. Biorheology1, 139, 1963
Charm, S.E., Nelson, F.: Red cell deformation and flow in capillaries. Bibl. anat.9, 246, 1967
Guest, M.M., Bond, T.P., Copper, R.G., Derrick, J.R.: Red blood cells: Change in shape in capillaries. Science142, 1319, 1963
Schmid-Schönbein, H.: Erythrocyte rheology and the optimization of mass transport in the microcirculation. Blood Cells1, 285, 1975
Skalak, R., Brånemark, P.-I.: Deformation of red blood cells in capillaries. Science164, 717, 1969
Skalak, R., Brånemark, P.-I., Ekholm, R.: Erythrocyte adherence and diapedesis. Some aspects of a possible mechanism based on vital and electron microscopic observations. Angiology21, 224, 1970
Skalak, R., Brånemark, P.-I.: Deformation of red blood cells in capillaries. Science164, 717–719, 1969
Bagge, U.: White blood cell rheology. Experimental studies on the rheological properties of white blood cells in man and rabbit and in an in vitro micro-flow system. Diss. Gothenburg University, 1975
Asano, M., Brånemark, P.-I.: Cardiovascular and microvascular responses to smoking in man. Adv. Microcirc.3, 125–158, 1970
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1978 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Brånemark, PI., Bagge, U. (1978). Intravascular Rheology of Erythrocytes in Man. In: Bessis, M., Shohet, S.B., Mohandas, N. (eds) Red Cell Rheology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-67059-6_1
Download citation
DOI: https://doi.org/10.1007/978-3-642-67059-6_1
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-09001-4
Online ISBN: 978-3-642-67059-6
eBook Packages: Springer Book Archive