Skip to main content

Prevention and Management of Cartilage Injury and Osteoarthritis from Sports

  • Chapter
  • First Online:
European Instructional Lectures

Part of the book series: European Instructional Lectures ((EICL,volume 13))

  • 1189 Accesses

Abstract

Articular cartilage defects in the knee of young or active individuals remain a problem in Orthopaedic practice. These defects have limited ability to heal and may progress to osteoarthritis (OA). The prevalence of knee OA among athletes is higher than the non-athletic population. The clinical symptoms of OA are joint pain, limitation of range of motion, joint swelling and joint stiffness. The diagnosis of OA is confirmed by the symptoms of the patient and the radiological findings (narrowing of joint space, osteophyte formation, and subchondral sclerosis). However, there is no strong correlation between the symptoms and the radiographic findings.

The aetiology of knee OA is multi-factorial. Excessive musculoskeletal loading (at work or in sports), high body mass index, previous knee injury, female gender and muscle weakness are well known risk factors. The high level athlete who has sustained a major knee injury has a high incidence of knee OA. Cartilage injuries are frequently observed in young and middle-aged active athletes. Often this injury precedes OA.

Reducing risk factors can decrease the prevalence of knee OA. The prevention of the knee injury, especially anterior cruciate ligament (ACL) injury in sports, is important to reduce and avoid progression of the knee OA.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Woolf AD, Pfleger B (2003) Burden of major musculoskeletal conditions. Bull World Health Organ 81(9):646–656

    PubMed  Google Scholar 

  2. Toivanen AT et al (2010) Obesity, physically demanding work and traumatic knee injury are major risk factors for knee osteoarthritis – a population-based study with a follow-up of 22 years. Rheumatology (Oxford) 49(2):308–314

    Article  Google Scholar 

  3. Cooper C et al (2000) Risk factors for the incidence and progression of radiographic knee osteoarthritis. Arthritis Rheum 43(5):995–1000

    Article  PubMed  CAS  Google Scholar 

  4. Thelin N, Holmberg S, Thelin A (2006) Knee injuries account for the sports-related increased risk of knee osteoarthritis. Scand J Med Sci Sports 16(5):329–333

    Article  PubMed  CAS  Google Scholar 

  5. Felson DT et al (2000) Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 133(8):635–646

    Article  PubMed  CAS  Google Scholar 

  6. Felson DT et al (1987) The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study. Arthritis Rheum 30(8):914–918

    Article  PubMed  CAS  Google Scholar 

  7. Lawrence JS (1977) Rheumatism in populations. Hienemann Medical, London

    Google Scholar 

  8. Felson DT (2004) An update on the pathogenesis and epidemiology of osteoarthritis. Radiol Clin North Am 42(1):1–9, v

    Article  PubMed  Google Scholar 

  9. Roos H et al (1994) The prevalence of gonarthrosis and its relation to meniscectomy in former soccer players. Am J Sports Med 22(2):219–222

    Article  PubMed  CAS  Google Scholar 

  10. Kujala UM et al (1995) Knee osteoarthritis in former runners, soccer players, weight lifters, and shooters. Arthritis Rheum 38(4):539–546

    Article  PubMed  CAS  Google Scholar 

  11. Turner AP, Barlow JH, Heathcote-Elliott C (2000) Long term health impact of playing professional football in the United Kingdom. Br J Sports Med 34(5):332–336

    Article  PubMed  CAS  Google Scholar 

  12. Drawer S, Fuller CW (2001) Propensity for osteoarthritis and lower limb joint pain in retired professional soccer players. Br J Sports Med 35(6):402–408

    Article  PubMed  CAS  Google Scholar 

  13. Chakravarty EF et al (2008) Long distance running and knee osteoarthritis. A prospective study. Am J Prev Med 35(2):133–138

    Article  PubMed  Google Scholar 

  14. Kuettner KE, Goldberg VM (1995) Introduction. In: Kuettner KE, Goldberg VM (eds) Osteoarthritis disorders. American Academy of Orthpaedic Surgeons, Rosemont

    Google Scholar 

  15. Kellgren JH, Lawrence JS (1957) Radiological assessment of osteo-arthrosis. Ann Rheum Dis 16(4):494–502

    Article  PubMed  CAS  Google Scholar 

  16. Bedson J, Croft PR (2008) The discordance between clinical and radiographic knee osteoarthritis: a systematic search and summary of the literature. BMC Musculoskelet Disord 9:116

    Article  PubMed  Google Scholar 

  17. Rall KL, McElroy GL, Keats TE (1964) A study of long term effects of football injury to the knee. Mo Med 61:435–438

    PubMed  CAS  Google Scholar 

  18. Gelber AC et al (2000) Joint injury in young adults and risk for subsequent knee and hip osteoarthritis. Ann Intern Med 133(5):321–328

    Article  PubMed  CAS  Google Scholar 

  19. Sutton AJ et al (2001) A case–control study to investigate the relation between low and moderate levels of physical activity and osteoarthritis of the knee using data collected as part of the Allied Dunbar National Fitness Survey. Ann Rheum Dis 60(8):756–764

    Article  PubMed  CAS  Google Scholar 

  20. Brown TD et al (1988) Contact stress aberrations following imprecise reduction of simple tibial plateau fractures. J Orthop Res 6(6):851–862

    Article  PubMed  CAS  Google Scholar 

  21. Huber-Betzer H, Brown TD, Mattheck C (1990) Some effects of global joint morphology on local stress aberrations near imprecisely reduced intra-articular fractures. J Biomech 23(8):811–822

    Article  PubMed  CAS  Google Scholar 

  22. Neyret P, Donell ST, Dejour H (1993) Results of partial meniscectomy related to the state of the anterior cruciate ligament. Review at 20 to 35 years. J Bone Joint Surg Br 75(1):36–40

    PubMed  CAS  Google Scholar 

  23. von Porat A, Roos EM, Roos H (2004) High prevalence of osteoarthritis 14 years after an anterior cruciate ligament tear in male soccer players: a study of radiographic and patient relevant outcomes. Ann Rheum Dis 63(3):269–273

    Article  Google Scholar 

  24. Nebelung W, Wuschech H (2005) Thirty-five years of follow-up of anterior cruciate ligament-deficient knees in high-level athletes. Arthroscopy 21(6):696–702

    Article  PubMed  Google Scholar 

  25. Ait Si Selmi T, Fithian D, Neyret P (2006) The evolution of osteoarthritis in 103 patients with ACL reconstruction at 17 years follow-up. Knee 13(5):353–358

    Article  PubMed  CAS  Google Scholar 

  26. Oiestad BE et al (2010) Knee function and prevalence of knee osteoarthritis after anterior cruciate ligament reconstruction: a prospective study with 10 to 15 years of follow-up. Am J Sports Med 38(11):2201–2210

    Article  PubMed  Google Scholar 

  27. Gillquist J, Messner K (1999) Anterior cruciate ligament reconstruction and the long-term incidence of gonarthrosis. Sports Med 27(3):143–156

    Article  PubMed  CAS  Google Scholar 

  28. Oiestad BE et al (2009) Knee osteoarthritis after anterior cruciate ligament injury: a systematic review. Am J Sports Med 37(7):1434–1443

    Article  PubMed  Google Scholar 

  29. Spector TD et al (1996) Risk of osteoarthritis associated with long-term weight-bearing sports: a radiologic survey of the hips and knees in female ex-athletes and population controls. Arthritis Rheum 39(6):988–995

    Article  PubMed  CAS  Google Scholar 

  30. Sandmark H, Vingard E (1999) Sports and risk for severe osteoarthrosis of the knee. Scand J Med Sci Sports 9(5):279–284

    Article  PubMed  CAS  Google Scholar 

  31. Roddy E et al (2005) Evidence-based recommendations for the role of exercise in the management of osteoarthritis of the hip or knee – the MOVE consensus. Rheumatology (Oxford) 44(1):67–73

    Article  CAS  Google Scholar 

  32. Deacon A et al (1997) Osteoarthritis of the knee in retired, elite Australian Rules footballers. Med J Aust 166(4):187–190

    PubMed  CAS  Google Scholar 

  33. Buckwalter JA, Lane NE (1997) Athletics and osteoarthritis. Am J Sports Med 25(6):873–881

    Article  PubMed  CAS  Google Scholar 

  34. Buckwalter JA, Lane NE (1997) Does participation in sports cause osteoarthritis? Iowa Orthop J 17:80–89

    PubMed  CAS  Google Scholar 

  35. Aroen A et al (2004) Articular cartilage lesions in 993 consecutive knee arthroscopies. Am J Sports Med 32(1):211–215

    Article  PubMed  Google Scholar 

  36. Brittberg M et al (1994) Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med 331(14):889–895

    Article  PubMed  CAS  Google Scholar 

  37. Krishnan SP et al (2006) Collagen-covered autologous chondrocyte implantation for osteochondritis dissecans of the knee: two- to seven-year results. J Bone Joint Surg Br 88(2):203–205

    Article  PubMed  CAS  Google Scholar 

  38. Bartlett W et al (2005) Autologous chondrocyte implantation versus matrix-induced autologous chondrocyte implantation for osteochondral defects of the knee: a prospective, randomised study. J Bone Joint Surg Br 87(5):640–645

    Article  PubMed  CAS  Google Scholar 

  39. Nehrer S et al (2006) Three-year clinical outcome after chondrocyte transplantation using a hyaluronan matrix for cartilage repair. Eur J Radiol 57(1):3–8

    Article  PubMed  CAS  Google Scholar 

  40. Behrens P et al (2006) Matrix-associated autologous chondrocyte transplantation/implantation (MACT/MACI) – 5-year follow-up. Knee 13(3):194–202

    Article  PubMed  Google Scholar 

  41. Steinwachs M, Kreuz PC (2007) Autologous chondrocyte implantation in chondral defects of the knee with a type I/III collagen membrane: a prospective study with a 3-year follow-up. Arthroscopy 23(4):381–387

    Article  PubMed  Google Scholar 

  42. van den Berg WB et al (2001) Growth factors and cartilage repair. Clin Orthop Relat Res (391 Suppl):S244–S250

    Article  Google Scholar 

  43. Engebretsen L, Arendt E, Fritts HM (1993) Osteochondral lesions and cruciate ligament injuries. MRI in 18 knees. Acta Orthop Scand 64(4):434–436

    Article  PubMed  CAS  Google Scholar 

  44. Wei X, Messner K (1999) Maturation-dependent durability of spontaneous cartilage repair in rabbit knee joint. J Biomed Mater Res 46(4):539–548

    Article  PubMed  CAS  Google Scholar 

  45. Twyman RS, Desai K, Aichroth PM (1991) Osteochondritis dissecans of the knee. A long-term study. J Bone Joint Surg Br 73(3):461–464

    PubMed  CAS  Google Scholar 

  46. Sharma L et al (1998) Knee adduction moment, serum hyaluronan level, and disease severity in medial tibiofemoral osteoarthritis. Arthritis Rheum 41(7):1233–1240

    Article  PubMed  CAS  Google Scholar 

  47. Honkonen SE (1995) Degenerative arthritis after tibial plateau fractures. J Orthop Trauma 9(4):273–277

    Article  PubMed  CAS  Google Scholar 

  48. Buckwalter JA, Mankin HJ (1998) Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr Course Lect 47:487–504

    PubMed  CAS  Google Scholar 

  49. Knutsen G et al (2004) Autologous chondrocyte implantation compared with microfracture in the knee. A randomized trial. J Bone Joint Surg Am 86-A(3):455–464

    PubMed  Google Scholar 

  50. Gudas R et al (2006) Osteochondral autologous transplantation versus microfracture for the treatment of articular cartilage defects in the knee joint in athletes. Knee Surg Sports Traumatol Arthrosc 14(9):834–842

    Article  PubMed  Google Scholar 

  51. Knutsen G et al (2007) A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years. J Bone Joint Surg Am 89(10):2105–2112

    Article  PubMed  Google Scholar 

  52. Steadman JR et al (2003) Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy 19(5):477–484

    Article  PubMed  Google Scholar 

  53. Namdari S et al (2009) Results and performance after microfracture in National Basketball Association athletes. Am J Sports Med 37(5):943–948

    Article  PubMed  Google Scholar 

  54. Riyami M, Rolf C (2009) Evaluation of microfracture of traumatic chondral injuries to the knee in professional football and rugby players. J Orthop Surg Res 4:13

    Article  PubMed  Google Scholar 

  55. Gobbi A, Nunag P, Malinowski K (2005) Treatment of full thickness chondral lesions of the knee with microfracture in a group of athletes. Knee Surg Sports Traumatol Arthrosc 13(3):213–221

    Article  PubMed  Google Scholar 

  56. Peterson L et al (2000) Two- to 9-year outcome after autologous chondrocyte transplantation of the knee. Clin Orthop Relat Res 374:212–234

    Article  PubMed  Google Scholar 

  57. Minas T (2001) Autologous chondrocyte implantation for focal chondral defects of the knee. Clin Orthop Relat Res (391 Suppl):S349–S361

    Article  Google Scholar 

  58. Peterson L et al (2002) Autologous chondrocyte transplantation. Biomechanics and long-term durability. Am J Sports Med 30(1):2–12

    PubMed  Google Scholar 

  59. Bentley G et al (2003) A prospective, randomised comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee. J Bone Joint Surg Br 85(2):223–230

    Article  PubMed  CAS  Google Scholar 

  60. Horas U et al (2003) Autologous chondrocyte implantation and osteochondral cylinder transplantation in cartilage repair of the knee joint. A prospective, comparative trial. J Bone Joint Surg Am 85-A(2):185–192

    PubMed  CAS  Google Scholar 

  61. Dozin B et al (2005) Comparative evaluation of autologous chondrocyte implantation and mosaicplasty: a multicentered randomized clinical trial. Clin J Sport Med 15(4):220–226

    Article  PubMed  Google Scholar 

  62. Muellner T et al (2001) Failed autologous chondrocyte implantation. Complete atraumatic graft delamination after two years. Am J Sports Med 29(4):516–519

    PubMed  CAS  Google Scholar 

  63. Saris DB et al (2009) Treatment of symptomatic cartilage defects of the knee: characterized chondrocyte implantation results in better clinical outcome at 36 months in a randomized trial compared to microfracture. Am J Sports Med 37(Suppl 1):10S–19S

    Article  PubMed  Google Scholar 

  64. Kreuz PC et al (2007) Importance of sports in cartilage regeneration after autologous chondrocyte implantation: a prospective study with a 3-year follow-up. Am J Sports Med 35(8):1261–1268

    Article  PubMed  Google Scholar 

  65. Kreuz PC et al (2006) Results after microfracture of full-thickness chondral defects in different compartments in the knee. Osteoarthritis Cartilage 14(11):1119–1125

    Article  PubMed  CAS  Google Scholar 

  66. Iwasa J et al (2009) Clinical application of scaffolds for cartilage tissue engineering. Knee Surg Sports Traumatol Arthrosc 17(6):561–577

    Article  PubMed  Google Scholar 

  67. Bobic V (1996) Arthroscopic osteochondral autograft transplantation in anterior cruciate ligament reconstruction: a preliminary clinical study. Knee Surg Sports Traumatol Arthrosc 3(4):262–264

    Article  PubMed  CAS  Google Scholar 

  68. Hangody L et al (2001) Mosaicplasty for the treatment of articular defects of the knee and ankle. Clin Orthop Relat Res (391 Suppl):S328–S336

    Article  Google Scholar 

  69. Safran MR, Kim H, Zaffagnini S (2008) The use of scaffolds in the management of articular cartilage injury. J Am Acad Orthop Surg 16(6):306–311

    PubMed  Google Scholar 

  70. Williams RJ, Gamradt SC (2008) Articular cartilage repair using a resorbable matrix scaffold. Instr Course Lect 57:563–571

    PubMed  Google Scholar 

  71. Kerker JT, Leo AJ, Sgaglione NA (2008) Cartilage repair: synthetics and scaffolds: basic science, surgical techniques, and clinical outcomes. Sports Med Arthrosc 16(4):208–216

    Article  PubMed  Google Scholar 

  72. Koga H et al (2009) Mesenchymal stem cell-based therapy for cartilage repair: a review. Knee Surg Sports Traumatol Arthrosc 17(11):1289–1297

    Article  PubMed  Google Scholar 

  73. Salzmann GM et al (2009) Sporting activity after high tibial osteotomy for the treatment of medial compartment knee osteoarthritis. Am J Sports Med 37(2):312–318

    Article  PubMed  Google Scholar 

  74. Bradbury N et al (1998) Participation in sports after total knee replacement. Am J Sports Med 26(4):530–535

    PubMed  CAS  Google Scholar 

  75. Fisher N et al (2006) Sporting and physical activity following Oxford medial unicompartmental knee arthroplasty. Knee 13(4):296–300

    Article  PubMed  CAS  Google Scholar 

  76. Naal FD et al (2007) Return to sports and recreational activity after unicompartmental knee arthroplasty. Am J Sports Med 35(10):1688–1695

    Article  PubMed  Google Scholar 

  77. Hopper GP, Leach WJ (2008) Participation in sporting activities following knee replacement: total versus unicompartmental. Knee Surg Sports Traumatol Arthrosc 16(10):973–979

    Article  PubMed  Google Scholar 

  78. Walton NP et al (2006) Patient-perceived outcomes and return to sport and work: TKA versus mini-­incision unicompartmental knee arthroplasty. J Knee Surg 19(2):112–116

    PubMed  Google Scholar 

  79. Hochberg M (2002) Prevention of lower limb osteoarthritis: data from the Johns Hopkins Precursors Study. In: Hascall VC, Kuettner KE (eds) The many faces of osteoarthritis. Birkhauser, Basel, pp 31–37

    Chapter  Google Scholar 

  80. Felson DT (1998) Preventing knee and hip osteoarthritis. Bull Rheum Dis 47(7):1–4

    PubMed  CAS  Google Scholar 

  81. Felson DT et al (1991) Occupational physical demands, knee bending, and knee osteoarthritis: results from the Framingham Study. J Rheumatol 18(10):1587–1592

    PubMed  CAS  Google Scholar 

  82. Felson DT et al (1992) Weight loss reduces the risk for symptomatic knee osteoarthritis in women. The Framingham Study. Ann Intern Med 116(7):535–539

    Article  PubMed  CAS  Google Scholar 

  83. Manninen P et al (1996) Overweight, gender and knee osteoarthritis. Int J Obes Relat Metab Disord 20(6):595–597

    PubMed  CAS  Google Scholar 

  84. Zhang W et al (2008) OARSI recommendations for the management of hip and knee osteoarthritis, part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage 16(2):137–162

    Article  PubMed  CAS  Google Scholar 

  85. Smith W, Walter J Jr, Bailey M (1985) Effects of insoles in Coast Guard basic training footwear. J Am Podiatr Med Assoc 75(12):644–647

    PubMed  CAS  Google Scholar 

  86. Sitler M et al (1990) The efficacy of a prophylactic knee brace to reduce knee injuries in football. A prospective, randomized study at West Point. Am J Sports Med 18(3):310–315

    Article  PubMed  CAS  Google Scholar 

  87. Olsen OE et al (2005) Exercises to prevent lower limb injuries in youth sports: cluster randomised controlled trial. BMJ 330(7489):449

    Article  PubMed  Google Scholar 

  88. Myklebust G et al (2003) Prevention of anterior cruciate ligament injuries in female team handball players: a prospective intervention study over three seasons. Clin J Sport Med 13(2):71–78

    Article  PubMed  Google Scholar 

  89. Soligard T et al (2008) Comprehensive warm-up programme to prevent injuries in young female footballers: cluster randomised controlled trial. BMJ 337:a2469

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lars Engebretsen MD, PhD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 EFORT

About this chapter

Cite this chapter

Takeda, H., Engebretsen, L. (2013). Prevention and Management of Cartilage Injury and Osteoarthritis from Sports. In: Bentley, G. (eds) European Instructional Lectures. European Instructional Lectures, vol 13. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36149-4_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-36149-4_18

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-36148-7

  • Online ISBN: 978-3-642-36149-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics