Overview
- Cutting-edge technologies for transporter studies in drug discovery and development
- Transporter structure-function studies and drug treatments in various diseases
- Latest developments in pharmacogenomics, systems biology, and bioinformatics
- Step-by-step methods with tips on troubleshooting and avoiding known pitfalls
- Wide-ranging and practical protocols by leading researchers in the field
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 637)
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Table of contents (19 protocols)
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Front Matter
Keywords
About this book
Studies of membrane transporters have had a great impact on our understanding of human diseases and the design of effective drugs. In Membrane Transporters in Drug Discovery and Development: Methods and Protocols, expert researchers provide practical methodologies of the ongoing research on membrane transporters, considering applications of transporter technologies in drug discovery and development. Chapters include new and useful fields and methodologies, including pharmacogenomics, nutrigenomics, systems biology, bioinformatics, nuclear magnetic resonance (NMR), imaging, and quantitative real-time-PCR. Transporter studies in drug discovery and development for various diseases are discussed, including neuropsychiatric disorders, cardiovascular diseases, ophthalmic diseases, cancer, and diabetes. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.
Wide-ranging and current, Membrane Transporters in Drug Discovery and Development: Methods and Protocols delivers a collection of practical protocols that can be used immediately in the lab, along with critical surveys of key topics by leading researchers in the field.
Reviews
From the reviews:
“This book forms part of the very large and well regarded Methods in Molecular Biology series, of which it is volume 637. Perhaps surprisingly, given its subtitle of Methods and Protocols, it includes not only protocols, but also reviews of a number of relevant areas of transporter biology … . In summary, this volume provides a very useful collection of up-to-date protocols for any scientist interested in the role of membrane transporters in drug action and drug development.” (Steve Baldwin, BTS Newsletter, Issue 37, Winter, 2010)
“This book describes various methodologies used in ongoing research on membrane transporters and discusses the roles of transporters in various diseases. … The book does a good job of reviewing the key methodologies used in this research. It is written for biomedical researchers who are interested in membrane transporters and drug development. Graduate students and postdoctoral researchers in the membrane transporter field will find it very useful. … It provides a good overview of methodologies used in the membrane transporter research field.” (Yi M. Weaver, Doody’s Review Service, July, 2010)
Editors and Affiliations
Bibliographic Information
Book Title: Membrane Transporters in Drug Discovery and Development
Book Subtitle: Methods and Protocols
Editors: Qing Yan
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-60761-700-6
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Humana Press 2010
Hardcover ISBN: 978-1-60761-699-3Published: 26 April 2010
Softcover ISBN: 978-1-4939-5733-0Published: 23 August 2016
eBook ISBN: 978-1-60761-700-6Published: 26 April 2010
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIII, 365
Topics: Human Physiology, Pharmacology/Toxicology, Membrane Biology