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Line bisection in medication-overuse and chronic tension-type headaches

  • Research Article
  • Published:
Translational Neuroscience

Abstract

Background

Both medication-overuse headache (MOH) and drug dependence share similar clinical features and the latter displays some deficits in visuospatial attention. The line bisection performance might help to indicate whether there is also a disruption in the visuospatial attention in MOH.

Methods

We administered the line bisection test and measured anxiety and depression levels in 21 patients with MOH, 26 patients with chronic tension-type headaches (CTTH) and in 22 healthy volunteers.

Results

On average, MOH patients significantly bisected leftward when referring to both frequency and magnitude, whereas the healthy volunteers and CTTH patients bisected slightly rightward. The levels of anxiety and depression were elevated in both MOH and CTTH patients compared to healthy volunteers, but the anxiety / depression levels were not correlated with the line bisection errors in all participants.

Conclusions

We found a pronounced pseudoneglect in MOH, which might indicate a relatively hyperactive right or hypoactive left hemisphere, or both, suggesting the disorder’s neuropsychological mechanism might overlap with that of drug dependence.

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Authors and Affiliations

  1. Department of Clinical Psychology and Psychiatry/School of Public Health, Zhejiang University College of Medicine, Hangzhou, Zhejiang, 310058, China

    Jinhua Zhang, Qianqian Gao, Hongying Fan & Wei Wang

  2. Department of Neurology, Zhejiang Provincial People’s Hospital, Hangzhou, Zhejiang, 310014, China

    Jinhua Zhang, Yu Geng & Huaqiao Tan

  3. Department of Psychiatry, Zhejiang Provincial People’s Hospital, Hangzhou, Zhejiang, 310014, China

    Enyan Yu & Wei Wang

Authors
  1. Jinhua Zhang
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  2. Qianqian Gao
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  3. Hongying Fan
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  4. Enyan Yu
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  5. Yu Geng
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  6. Huaqiao Tan
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  7. Wei Wang
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Correspondence to Wei Wang.

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Zhang, J., Gao, Q., Fan, H. et al. Line bisection in medication-overuse and chronic tension-type headaches. Translat.Neurosci. 5, 117–122 (2014). https://doi.org/10.2478/s13380-014-0216-8

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  • DOI: https://doi.org/10.2478/s13380-014-0216-8

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