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Effects of pain on activities of daily living and functioning in Parkinson’s disease patients

  • Research Article
  • Published:
Translational Neuroscience

Abstract

Objective

To investigate how pain affects Parkinson’s disease (PD) patients in their activities of daily living (ADL) and functioning, and to identify correlations among ADL and types of pain, pain locations, and demographics.

Methods

The study population comprised 104 PD patients who reported feeling pain. Patients indicated whether pain affected particular actions, including standing, walking, and laboring. Patients further reported the functional effects of pain on their emotional and social health. Data was collected using self-made questionnaires.

Results

Overall, akathisic pain was the most effective predictor of negative effects of pain on ADL. The presence of akathisic pain increased the likelihood of mobility problems by almost 4.0-fold (p = 0.024), exhaustion by 10.0-fold (p = 0.017), social functioning problems by 3.5-fold (p = 0.037), lack of enjoyment in life by approximately 4.0-fold (p = 0.017) and problems in emotional functioning by 3.6-fold (p = 0.025). In addition, it was found that the duration of PD was correlated to problems with daily work (p = 0.033); Hoehn and Yahr stage of PD at diagnosis was correlated to exhaustion (p = 0.013); and male gender was correlated to a lack of perceived enjoyment of life (p = 0.010).

Conclusion

Pain is a debilitating symptom of PD patients, and has a negative impact on ADL. Thus, medical professionals should seriously consider the effects of pain in deciding the optimum therapeutic approach for PD patients.

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Authors and Affiliations

  1. Parkinson’s Clinic of Eastern, Toronto and Movement Disorders Centre, Toronto, Ontario, Canada

    Abdul Qayyum Rana

  2. Department of Neurology, Cleveland Clinic, Florida and Movement Disorders Centre, Weston, Florida, USA

    Tarannum S. Khan

  3. Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada

    Patrick Galange & Adeel Khan

  4. Faculty of Neuroscience, University of Toronto, Toronto, Ontario, Canada

    Muhammad Saad Yousuf

Authors
  1. Abdul Qayyum Rana
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  2. Tarannum S. Khan
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  3. Patrick Galange
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  4. Adeel Khan
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  5. Muhammad Saad Yousuf
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Correspondence to Abdul Qayyum Rana.

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Rana, A.Q., Khan, T.S., Galange, P. et al. Effects of pain on activities of daily living and functioning in Parkinson’s disease patients. Translat.Neurosci. 3, 328–333 (2012). https://doi.org/10.2478/s13380-012-0038-5

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  • DOI: https://doi.org/10.2478/s13380-012-0038-5

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