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Comparing mixture estimates by parametric bootstrapping likelihood ratios

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Abstract

Wildlife managers and researchers often need to estimate the relative contributions of distinct populations in a miture of organisms. Increasingly, there is interest in comparing these mixture contributions across space or time. Comparisons usually just check for overlap in the interval estimates for each population contribution from each mixture. This method inflates Type I error rates, has limited power due to its focus on marginal comparisons, and employs a fundamentally inappropriate measure of mixture difference. Given the difficulty of defining an appropriate measure of mixture difference, a powerful alternative is to compare mixtures using a likelihood ratio test. In applications where the standard asymptotic theory does not hold, the null reference distribution can be obtained through parametric bootstrapping. In addition to testing simple hypotheses, a likelihood ratio framework encourages modeling the change in mixture contributions as a function of covariates. The method is demonstrated with an analysis of potential sampling bias in the estimation of population contributions to the commercial sockeye, salmon (Oncorhynchus nerka) fishery in Upper Cook Inlet, Alaska.

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References

  • ADF&G (2000), “SPAM version 3.2 User’s Guide: Statistics Program for Analyzing Mixtures,” Special Publication No. 15, Alska Department of Fish and Game. Division of Commercial Fisheries. Anchorage, AK, http: //www.cf.adfg.state.ak.us/geninfo/research/genetics/Software/Spam Page.html.

  • Aitchison, J. (1982), “The Statistical Analysis of Compositional Data” (with discussion). Journal of the Royal Statistical Society, Ser. B, 44, 139–177.

    MATH  MathSciNet  Google Scholar 

  • — (1986) The Statistical Analysis of Compositional Data, New York: Chapman and Hall.

    MATH  Google Scholar 

  • — (1992), “On Criteria for Measures of Compositional Difference,” Mathematical Geology, 24, 365–379.

    Article  MATH  MathSciNet  Google Scholar 

  • Allendorf, F. W., and Phelps, S. R. (1981), “Use of Allelic Frequencies to Describe Population Structure” Canadian Journal of Fisheries and Aquatic Sciences, 38, 1507–1514.

    Article  Google Scholar 

  • Begg, G. A., Friedland, K. D., and Pearce, J. B. (1999), “Stock Identification—Its Role in Stock Assessment and Fisheries Management: A Selection of Papers Presented at a Symposium of the 128th Annual Meeting of the American Fisheries Society in Hartford, Connecticut, USA, 23–27 August 1998,” Fisheries Research, 43, 1–3.

    Article  Google Scholar 

  • Billheimer, D., Guttorp, P., and Fagan, W. F. (2001), “Statistical Interpretation of Species Composition,” Journal of the American Statistical Association, 96, 1205–1214.

    Article  MATH  MathSciNet  Google Scholar 

  • Blischke, W. R. (1963), “Mixtures of Discrete Distributions,” in Proceedings of the International Symposium on Classical and Contagions Discrete Distributions, New York: Pergamon Press, pp. 351–372.

    Google Scholar 

  • Burgner, R. L. (1991) “Life History of Sockeye Salmon (Oncorhynchusnerka),” Pacific Salmon Life Histories, eds. C. Groot and L. Margolis, Vancouver, BC: University of British Columbia Press, pp. 3–117.

    Google Scholar 

  • Cassie, R. M. (1954), “Some Uses of Probability Paper in the Analysis of Size Frequency Distributions,” Australian Journal of Marine and Freshwater Research, 5, 513–523.

    Google Scholar 

  • Cavalli-Sforza, L. L., and Edwards, A. W. F. (1967), “Phylogenetic Analysis: Models and Estimation Procedures,” Evolution, 21, 550–570.

    Article  Google Scholar 

  • Do, K.-A., and McLachlan, G. J. (1984), “Estimation of Mixing Proportions: A Case Study,” Applied Statistics, 33, 134–140.

    Article  Google Scholar 

  • Davison, A. C., and Hinkley, D. V. (1997), Bpotstrap Methodsand Their Application. Cambridge, UK: Cambridge University Press.

    Google Scholar 

  • Dempster, A. P., Laird, N. M., and Rubin, D. B. (1977), “Maximum Likelihood from Incomplete Data via the EM Algorithm,” Journal of the Royal Statistical Society, Ser. B. 39, 1–38.

    MATH  MathSciNet  Google Scholar 

  • Fournier, D. A., Beacham, T. D., Ridell, B. E., and Busack, C. A. (1984), “Estimating Stock Composition in Mixed Stock Fisheries using Morphometric, Meristic, and Electrophoretic Characteristics,” Canadian Journal of Fisheries and Aquatic Sciences, 41, 400–408.

    Article  Google Scholar 

  • Grant, W. S., Milner, G. B., Krasnowski, P., and Utter, F. M. (1980), “Use of Biochemical Genetic Variants for Identification of Sockeye Salmon (Onchorhynchusnerka) Stocks in Cook Inlet, Alaska,” Canadian Journal of Fisheries and Aquatic Sciences, 37, 1236–1247.

    Article  Google Scholar 

  • Hsu, J. C. (1996) Multiple Comparisons: Theory and Methods, London: Chapman and Hall.

    MATH  Google Scholar 

  • Ihssen, P. E., Booke, H. E., Casselman, J. M., McGlade, J. M., Payne, N. R., and Utter, F. M. (1981), “Stock Identification: Materials and Methods,” Canadian Journal of Fisheries and Aquatic Sciences, 38, 1838–1855.

    Article  Google Scholar 

  • Kiefer, J., and Wolfowitz, J. (1956) “Consistency of Maximum Likelihood Estimates in the Presence of Infinitely many Incidental Parameters,” Annals of Mathematical Statistics, 27, 887–907.

    Article  MATH  MathSciNet  Google Scholar 

  • Lindsay, B. G. (1995) Mixture Models: Theory, Geometry, and Applications, NSF-CBMS Regional Conference Series in Probability and Statistics (vol. 5), Alexandria, VA: Institute of Mathematical Statistics and the American Statistical Association.

    Google Scholar 

  • Marshall, S., Bernard, D., Conrad, R., Cross, B., McBride, D., McGregor, A., McPherson, S., Oliver, G., Sharr, S., and Van Allen, B. (1987), “Application of Scale Patterns Analysis to the Management of Alaska’s Sockeye Salmon (Onchorhynchus nerka) Fisheries,” in Sockeye Salmon (Oncorhynchus nerka) Population Biology and Future Management, eds. H. D. Smith, L. Margolis, and C. C. Wood, Canadian Special Publication on Fisheries and Aquatic Science 96, pp. 207–326.

  • McLachlan, G. (1987) “On Bootstrapping the Likelihood Ratio Test Statistic for the Number of Components in a Normal Mixture,” Applied Statistics, 36, 318–324.

    Article  Google Scholar 

  • McLachlan, G., and Peel, D. (2000) “Finite Mixture Models, New York: Wiley.

    Book  MATH  Google Scholar 

  • McParland, T. L., Ferguson, M. M., and Liskauskas, A. P. (1999), “Genetic Population Structure and Mixed-Stock Analysis of Walleyes in the Lake Eric-Lake Huron Corridor Using Allozy me and Mitochondrial DNA Markers,” Transactions of the American Fisheries Society, 128, 1055–1067.

    Article  Google Scholar 

  • Moles, A., and Jensen, K. (2000), “Prevalence of the Sockeye Salmon Brain Parasite Myxobolus arcticus in Selected Alaska Stream,” Alaska Fisheries Research Bulletin, 6, 85–93.

    Google Scholar 

  • Millar, R. B. (1987), “Maximum Likelihood Estimation of Mixed Stock Fishery Composition,” Canadian Journal of Fisheries and Aquatic Sciences, 44, 583–590.

    Article  Google Scholar 

  • Milner, G. B., Teel, D. J., Utter F. M., and Burley, C. L. (1981) “Columbia River Stock Identification Study: Validation of Genetic Method,” unpublished manuscript (final report of research (FY80) financed by Bonneville Power Administration Contract DE-A179-80BP18488), National Marine Fisheries Service, Northwest and Alaska Fisheries Center, Seattle, WA.

    Google Scholar 

  • Pearce, J. M., Pierson, B. J., Talbot, S. L., Derksen, D. V., Kraege, D., and Scribner, K. T. (2000), “A Genetic Evaluation of Morphology used to Identify Harvested Canada Geese,” Journal of Wildlife Management, 64, 863–874.

    Article  Google Scholar 

  • Pella, J. J., and Masuda, M. (2001), “Bayesian Methods for Stock-Mixture Analysis from Genetic Characters,” Fishery Bulletin, 99, 151–167.

    Google Scholar 

  • Pella, J. J., Masuda, M., and Nelson, S. (1996) “Search Algorithms for Computing Stock Composition of a Mixture From Traits of Individuals by Maximum Likelihood,” NOAA/NMFS Technical Memo NMFS-AFSC-6L. National Marine Fisheries Service, Northwest and Alaska Fisheries Center, Seattle, WA.

    Google Scholar 

  • Pella, J. J., and Milner, G. B. (1987), “Use of Genetic Marks in Stock Composition Analysis,” in Population Genetics and Fishery Management, eds. N. Ryman and F. Utter, Seattle, WA: Washington Sea Grant Program, pp. 247–276.

    Google Scholar 

  • Planes, S., and Doherty, P. J. (1997), “Genetic and Color Interactions at a Contact Zone of Acanthochromis polyacanthus. A Marine Fish Lacking Pelagic Larvae,” Evolution, 51, 1232–1243.

    Article  Google Scholar 

  • Rannala, B., and Mountain, J. L. (1997), “Detecting Immigration by Using Multilocus Genotypes,” Proceedings of the National Academy of Sciences USA, 94, 9197–9201.

    Article  Google Scholar 

  • Redner, R. A., and Walker, H. F. (1984), “Mixture Densities, Maximum Likelihood and the EM Algorithm,” Society for Industrial and Applied Mathematics Review, 26, 195–239.

    MATH  MathSciNet  Google Scholar 

  • Reynolds, J. H. (2001) “SPAM (Statistics Program for Analyzing Mixtures) Version 3.5: User’s Guide Addendum,” Addendum to Special Publication No. 15, Alaska Dept. of Fish and Game, Division of Commercial Fisheries, Gene Conservation Laboratory, Anchorage, AK, http://www.cf.adfg.state.ak.us/geninfo/research/genetics/Software/SpamPage.htm.

    Google Scholar 

  • Ruesch, P.H., and Fox, J., (1999), “Upper Cook Inlet Commercial Fisheries Annual Management Report, 1998,” Regional Information Report No. 2A99-21. Alaska Department of Fish and Game, Division of Commercial Fisheries, Anchorage, AK.

    Google Scholar 

  • Ruzzante, D. E., Taggart, C. T., Lang, S., and Cook, D. (2000), “Mixed-Stock Analysis of Atlantic Cod Near the Gulf of St. Lawrence Based on Microsatellite DNA,” Ecological Applications, 10, 1090–1109.

    Article  Google Scholar 

  • Saitou, N., and Nei, M. (1987) “The Neighbor-Joining Method: A New Method for Reconstructing Phylogenetic Trees,” Molecular Biology and Evolution, 4, 406–425.

    Google Scholar 

  • Seeb, L. W., and Crane, P. A. (1999), “Allozymes and Mitochondrial DNA Discriminate Asian and North American Populations of Chum Salmon in Mixed-Stock Fisheries Along the South Coast of the Alaska Peninsula,” Transactions of the American Fisheries Society, 128, 88–103.

    Article  Google Scholar 

  • Seeb, L. W., Habicht, C., Templin, W. D., Tarbox, K. E., Davis, R. Z., Brannian, L. K., and Seeb, J. E., (2000), “Genetic Diversity of Sockeye Salmon of Cook Inlet, Alaska, and its Application to Management of Populations Affected by the Exxon Valdez Oil Spill,” Transactions of the American Fisheries Society, 129, 1223–1249.

    Article  Google Scholar 

  • Self, S. G., and Liang, K. Y. (1987), “Asymptotic Properties of Maximum Likelihood Estimators and Likelihood Ratio Tests Under Nonstandard Conditions,” Journal of The American Statistical Association, 82, 605–610.

    Article  MATH  MathSciNet  Google Scholar 

  • Shaklee, J. B., Beacham, T. D., Seeb, L., and White, B. A. (1999), “Managing Fisheries Using Genetic Data: Case Studies from Four Species of Pacific Salmon,” Fisheries Research, 43, 45–78.

    Article  Google Scholar 

  • Smouse, P. E., Waples, R. S., and Tworek, J. A. (1990), “A Genetic Mixture Analysis for Use With Incomplete Source Population Data,” Canadian Journal of Fisheries and Aquatic Sciences, 47, 620–634.

    Article  Google Scholar 

  • Stuart, A., Ord, J. K., and Arnold, S. (1999) Kendall’s Advanced Theory of Statistics, (vol. 2A): Classical Inference and the Linear Model (6th ed.), New York: Oxford University Press.

    Google Scholar 

  • Teicher, H. (1963), “Identifiability of Finite Mixtures,” Annals of Mathematical Statistics, 34, 1265–1269.

    Article  MATH  MathSciNet  Google Scholar 

  • Titterington, D. M., Smith, A. F. M., and Makov, U. E. (1985), Statistical Analysis of Finite Mixture Distributions, New York: Wiley.

    MATH  Google Scholar 

  • Tobias, T., and Tarbox, K. E. (1999) “An Estimate of Total Return of Sockeye Salmon to Upper Cook Inlet, Alaska 1976–1998,” Regional Information Report 2A99-11, Alaska Department of Fish and Game, Division of Commercial Fisheries, Anchorage AK.

    Google Scholar 

  • Urawa, S., Nagasawa, K., Margolis, L., and Moles, A. (1998) “Stock Identification of Chinook Salmon (Onchorltynchus tshawytsha) in the North Pacific Ocean and Bering Sea by Parasite Tags,” North Pacific Anadromous Fish Commission Bulletin, 1, 199–204.

    Google Scholar 

  • Waltemeyer, D. L., Tarbox, K. E., and Brannian, L. K. (1993) “Presence of the Parasite Philonema oncorhynchic in Sockeye, Salmon Return to Upper Cook Inlet. Alaska in 1991,” Regional Information Report No. 2A93-24, Alaska Department of Fish and Game, Division of Commercial Fisheries, Anchorage, AK.

    Google Scholar 

  • Waples, R. S. (1990), “Temporal Changes of Allele Frequency in Pacific salmon—Implications for Mixed-Stock Fishery Analysis,” Canadian Journal of Fisheries and Aquatic Sciences, 47, 968–976.

    Article  Google Scholar 

  • Wilmot, R. L., Kondzela, C. M., Guthrie C. M., and Masuda, M. M. (1998), “Genetic Stock Identification of Chum Salmon Harvested Incidentally in the 1994 and 1995 Bering Sea Trawl Fishery,” North Pacific Anadronous Fish Commission Bulletin, 1, 285–299.

    Google Scholar 

  • Woody, C. A., Olsen, J., Reynolds, J., and Bentzen, P. (2000), “Temporal Variation in Phenotypic and Genotypic Traits in Two Sockeye Salmon Populations, Tustumena Lake, Alaska,” Transactions of the American Fisheries Society, 129, 1031–1043.

    Article  Google Scholar 

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Correspondence to Joel H. Reynolds.

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Reynolds, J.H., Templin, W.D. Comparing mixture estimates by parametric bootstrapping likelihood ratios. JABES 9, 57–74 (2004). https://doi.org/10.1198/1085711043145

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