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Conformational changes of a DNA molecule induced by metal complexes formed in solution

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Abstract

Changes in the tertiary structure of a high-molecular-mass DNA in solution that result from the addition of trivalent lanthanum ions, including intramolecular structuring of the macromolecule, are studied by atomic-force microscopy. The effect of bivalent magnesium and manganese ions on the structure of DNA in an aqueous-alcohol solution is analyzed. The data are compared with the results of viscometry, dynamic light scattering, flow birefringence, circular dichroism, and UV spectrophotometry.

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Authors and Affiliations

  1. Faculty of Physics, St. Petersburg State University, Ul’yanovskaya ul. 1, Petrodvorets, St. Petersburg, 198504, Russia

    N. A. Kasyanenko, D. A. Mukhin & I. Yu. Perevyazko

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  1. N. A. Kasyanenko
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  2. D. A. Mukhin
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  3. I. Yu. Perevyazko
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Correspondence to N. A. Kasyanenko.

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Original Russian Text © N.A. Kasyanenko, D.A. Mukhin, I.Yu. Perevyazko, 2010, published in Vysokomolekulyarnye Soedineniya, Ser. C, 2010, Vol. 52, No. 7, pp. 1360–1372.

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Kasyanenko, N.A., Mukhin, D.A. & Perevyazko, I.Y. Conformational changes of a DNA molecule induced by metal complexes formed in solution. Polym. Sci. Ser. C 52, 122–133 (2010). https://doi.org/10.1134/S1811238210010145

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  • DOI: https://doi.org/10.1134/S1811238210010145

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