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Comparative degradation study of surface-modified polyacrylamide/poly(3-hydroxybutyrate-co-3-hydroxyvalerate) membranes

  • Polymer Membranes
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Abstract

Hydrophilic poly(3-hydroxybutyrate-co-3-hydroxyvalerate)-based composites have been prepared aiming at extending in vivo application. Polyacrylamide was introduced into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) membranes via a surface-initiated polymerization, forming a semi-interpenetratinglike polymer networks that was surface-modified by Hofmann degradation reaction to obtain the amine-contained poly(3-hydroxybutyrate-co-3-hydroxyvalerate). The resulted amine groups were further reacted with collagen through formaldehyde. The swelling properties as well as thermal decomposition of the synthesized composites were studied. The composites were incubated in phosphate-buffered saline for up to 360 days and their weight-loss was determined.

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Authors and Affiliations

  1. Department of Biomedical Engineering, Key Laboratory of Biomaterials of Guangdong Higher Education Institutes, College of Life Science and Technology, Jinan University, Guangzhou, 510632, China

    Yu Ke & Xiaoye Zhang

  2. Biomaterial Research Institute, School of Materials Science and Engineering, South China University of Technology, Guangzhou, 510641, China

    Gang Wu & Li Ren

  3. National Engineering Research Center for Tissue Restoration and Reconstruction, Guangzhou, 510006, China

    Yingjun Wang

Authors
  1. Yu Ke
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  2. Xiaoye Zhang
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  3. Gang Wu
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  4. Li Ren
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  5. Yingjun Wang
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Correspondence to Yu Ke.

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Ke, Y., Zhang, X., Wu, G. et al. Comparative degradation study of surface-modified polyacrylamide/poly(3-hydroxybutyrate-co-3-hydroxyvalerate) membranes. Polym. Sci. Ser. B 57, 538–546 (2015). https://doi.org/10.1134/S156009041505005X

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  • DOI: https://doi.org/10.1134/S156009041505005X

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