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Monolithic methacrylate polymeric sorbents: Development of methods for chemical modification of the surface for the subsequent bioaffine functionalization

  • Macromolecular Chemistry and Polymeric Materials
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Abstract

Copolymers containing aldehyde, succinimidyl carbonate, and imidazolecarbamate groups were prepared by polymer-analogous transformations of epoxy groups of a macroporous monolithic polymeric support derived from glycidyl methacrylate and ethylene glycol dimethacyrlate. The effect of certain parameters on the course of the copolymer modification and immobilization of a protein on the surface of the polymeric support was studied. The possibility of using the matrices obtained for development of biorecognizing systems was examined.

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Authors and Affiliations

  1. Institute of Macromolecular Compounds, Russian Academy of Sciences, St. Petersburg, Russia

    E. S. Sinitsyna, E. N. Vlasova, E. G. Vlakh & T. B. Tennikova

Authors
  1. E. S. Sinitsyna
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  2. E. N. Vlasova
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  3. E. G. Vlakh
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  4. T. B. Tennikova
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Original Russian Text © E.S. Sinitsyna, E.N. Vlasova, E.G. Vlakh, T.B. Tennikova, 2008, published in Zhurnal Prikladnoi Khimii, 2008, Vol. 81, No. 8, pp. 1326–1332.

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Sinitsyna, E.S., Vlasova, E.N., Vlakh, E.G. et al. Monolithic methacrylate polymeric sorbents: Development of methods for chemical modification of the surface for the subsequent bioaffine functionalization. Russ J Appl Chem 81, 1403–1409 (2008). https://doi.org/10.1134/S1070427208080168

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  • DOI: https://doi.org/10.1134/S1070427208080168

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