Abstract
The interaction of molecules of bovine serum albumin (BSA) with silicon nanoparticles (SiNPs) was studied in water solutions of them at different pH values. The data of photon correlation spectroscopy and IR spectroscopy of studied solutions indicate the absence of interaction between BSA and SiNPs in the pH range 3–7, which is attested to by the experimentally obtained character of the pH dependence of the translational diffusion coefficient D t and by the absence of hydrogen bonds between the protein carbonyl groups and the OH groups on the surface of mesoporous silicon nanoparticles. The obtained data may play a leading role in further in vivo application of silicon nanoparticles.
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Original Russian Text © K.A. Anenkova, G.P. Petrova, V.V. Gibizova, L.A. Osminkina, K.P. Tamarov, 2013, published in Optika i Spektroskopiya, 2013, Vol. 115, No. 2, pp. 195–200.
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Anenkova, K.A., Petrova, G.P., Gibizova, V.V. et al. Optical properties of serum albumin water solutions, containing mesoporous silicon particles. Opt. Spectrosc. 115, 166–170 (2013). https://doi.org/10.1134/S0030400X1308002X
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DOI: https://doi.org/10.1134/S0030400X1308002X