Skip to main content
SpringerLink
Log in

In vitro antitumor activity of heterochitooligosaccharides (Review)

  • Published:
Applied Biochemistry and Microbiology Aims and scope Submit manuscript

Abstract

This review presents an analysis of the literature data over the last decade in order to reveal the relationship between the structure and composition of chitin/chitosan oligomers and their antitumor activity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ji, J., Wang, L., Wu, H., and Luan, H.M., Int. J. Biol., 2011, vol. 3, no. 1, pp. 74–86.

    CAS  Google Scholar 

  2. Ahmed, A.B.A., Taha, R.M., Mohajer, S.M., Elaagib, E., and Kim, S.K., Russ. J. Mar. Biol., 2012, vol. 38, no. 4, pp. 351–358.

    Article  CAS  Google Scholar 

  3. Il’ina, A.V., Levov, A.N., Mestechkina, N.M., Drozd, N.N., Orlov, V.N., Makarov, V.A., Shcherbukhin, V.D., Varlamov, V.P., and Skryabin, K.G., Ross. Nanotekhnol., 2009, vol. 4, no. 3–4, pp. 146–154.

    Google Scholar 

  4. Aam, B.B., Heggset, E.B., Norberg, A.L., Sorlie, M., Varum, K.M., and Eijsink, V.G.H., Mar. Drugs, 2010, vol. 8, no. 5, pp. 1482–1517.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  5. Gao, X-A., Zhang, Y.-F., Park, R.-D., Huang, X., Zhao, Y., Xie, J., and Jin, R., J. Appl. Biol. Chem., 2012, vol. 55, no. 1, p. 13.

    Article  Google Scholar 

  6. El-Sayed, S.T., El-Sayed, M., Shousha, W.G., Shehata, A.N., and Omar, N.I., Austral. J. Basic Appl. Sci., 2012, vol. 6, no. 4, pp. 1–15.

    CAS  Google Scholar 

  7. Assis, C.F., Melo-Selveira, R.F., Oliveira, R.M., Costa, L.S., Oliveira Rocha, H.A., Macedo, G.R., and Santos, E.S., J. Bioproces. Biotechniq., 2012, vol. 2, no. 2. http://dx.doi.org/10.4172/2155-9821.1000114

    Google Scholar 

  8. Sikorski, P., Stokke, B.T., Sorbotten, A., Varum, K.M., Horn, S.J., and Eijsink, V.G., Biopolymers, 2005, vol. 77, no. 5, pp. 273–285.

    Article  CAS  PubMed  Google Scholar 

  9. Shen, K.-T., Chen, M.-H., Chan, H.-Y., Jeng, J.-H., and Wang, Y.-J., Food Chem. Toxicol, 2009, vol. 47, no. 8, pp. 1864–1871.

    Article  CAS  PubMed  Google Scholar 

  10. Feng, J., Zhao, L., and Yu, Q., Biochem. Biophys. Res. Commun., 2004, vol. 317, no. 2, pp. 414–420.

    Article  CAS  PubMed  Google Scholar 

  11. Han, Y., Zhao, L., Yu, Z., Feng, J., and Yu, Q., Inter. Immunopharmacol., 2005, vol. 5, no. 10, pp. 1533–1542.

    Article  CAS  Google Scholar 

  12. Ngo, D.N., Kim, M.M., and Kim, S.K., Carbohydr. Res., 2008, vol. 74, no. 2, pp. 228–234.

    Article  CAS  Google Scholar 

  13. Xu, Q., Dou, J., Wei, P., Tan, C., Yun, X., Wu, Y., Bai, X., Ma, X., and Du, Y., Carbohydr. Res., 2008, vol. 71, no. 4, pp. 509–514.

    Article  CAS  Google Scholar 

  14. Costa, L.S., Melo-Silveira, R.F., Oliveira, R.M., Pagnoncelli, M.G.B., Rocha, H.A.O., Macedo, G.R., and Santos, E.S., J. Microbiol. Biotechnol., 2012, vol. 28, no. 3, pp. 1097–1105.

    Article  Google Scholar 

  15. Fernandes, J.C., Borges, M., Nascimento, H., Bronzeda-Rocha, E., Ramosa, O.S., Pintado, M.E., Malcata, F.X., and Santos-Silva, A., Inter. J. Biol. Macromol., 2011, vol. 49, no. 3, pp. 433–438.

    Article  CAS  Google Scholar 

  16. Chitin (ID), Muzzarelli, R.A.A., Ed., London, UK: Oxford Pergamon Press, 1977.

  17. Huang, R.E., Mendis, E., Rajapakse, N., and Kim, S., K, Life Sci. 2006, vol. 78, no. 20, pp. 2399–2408.

    Article  CAS  PubMed  Google Scholar 

  18. Xu, W., Jiang, C., Kong, X., Liang, Y., Rong, M., and Liu, W., Mol. Med. Rep., 2012, vol. 6, no. 2, pp. 385–390.

    CAS  PubMed  Google Scholar 

  19. Qin, C., Du, Y., Xiao, L., Li, Z., and Gao, X., Int. J. Biol. Macromol., 2002, vol. 31, nos. 1–3, pp. 111–117.

    Article  CAS  PubMed  Google Scholar 

  20. Maeda, Y. and Kimura, Y., J. Nutr., 2004, vol. 134, no. 4, pp. 945–950.

    CAS  PubMed  Google Scholar 

  21. Park, J.R., Chung, M.J., Choi, H.N., and Park, Y.I., Int. J. Mol. Sci., 2011, vol. 12, no. 1, pp. 266–277.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  22. Kerbel, R.S., Carcinogenes, 2000, vol. 21, no. 3, pp. 505–515.

    Article  CAS  Google Scholar 

  23. Diane, B., Kusumanto, Y., Meijer, C., Mulder, N.H., and Hospers, G.A.P., Pharm. Res., 2006, vol. 53, no. 1, pp. 89–103.

    Google Scholar 

  24. Wu, H., Yao, Z., Bai, X., Du, Y., and Lin, B., Carbohydr. Res., 2008, vol. 73, pp. 105–110.

    Article  CAS  Google Scholar 

  25. Xiong, C., Wu, H., Wei, P., Pan, M., Tuo, Y., Kusakabe, I., and Du, Y., Carbohydr. Res., 2009, vol. 344, no. 15, pp. 1975–1983.

    Article  CAS  PubMed  Google Scholar 

  26. Wang, Z., Zheng, L., Yang, S., Niu, R., Chu, E., and Lin, X., Biochem. Biophys. Res. Commun., 2007, vol. 357, no. 1, pp. 26–31.

    Article  CAS  PubMed  Google Scholar 

  27. Sun, Y., Liu, W., Han, B., Zhang, J., and Liu, B., Biotechnol. Lett., 2006, vol. 28, no. 17, pp. 1393–1399.

    Article  CAS  PubMed  Google Scholar 

  28. Prashanth, K.V. and Tharanathan, R.N., Bioch. Biophys. Acta, 2005, vol. 1722, no. 1, pp. 22–29.

    Article  CAS  Google Scholar 

  29. Nauta, A.J. and Garssen, J., Carbohydr. Res., 2013, vol. 93, no. 1, pp. 263–265.

    Article  CAS  Google Scholar 

  30. Hwang, H-J., Im, J-A., and Kim, S-H., J. Chitin Chitosan, 2009, vol. 14, no. 3, pp. D. 125–129.

    Google Scholar 

  31. Xia, W., Liu, P., Zhang, J., and Chen, J., Food Hydrocolloids, 2010, vol. 25, no. 2, pp. 170–179.

    Article  Google Scholar 

  32. Maqsood, S., Singh, P., Samoon, M.H., and Muni, K., Int. Aquat. Res., 2011, vol. 3, pp. 147–163.

    Google Scholar 

  33. Svirshchevskaya, E.V., Alekseeva, L.G., Reshetov, P.D., Phomicheva, N.N., Parphenyuk, S.A., Ilyina, A.V., Zueva, V.S., Lopatin, S.A., Levov, A.N., and Varlamov, V.P., Europ. J. Med. Chem., 2009, vol. 44, no. 5, pp. 2030–2037.

    Article  CAS  Google Scholar 

  34. Wu, G.J. and Tsai, G.J., Food Chem. Toxicol., 2007, vol. 45, no. 2, pp. 250–258.

    Article  CAS  PubMed  Google Scholar 

  35. Wei, X., Wanga, Y., Xiao, J., and Xia, W., Int. J. Biol. Macromol., 2009, vol. 45, no. 4, pp. 432–436.

    Article  CAS  PubMed  Google Scholar 

  36. Deng, X., Li, X., Liu, P., Yuan, S., Zang, J., Songyu, LiS., and Piao, X., Asian-Aust. J. Anim. Sci., 2008, vol. 21, no. 11, pp. 1651–1658.

    Article  CAS  Google Scholar 

  37. Chitosan, Skryabin, K.G., Mikhailov, S.N., and Varlamov, V.P., Eds., Moscow: Centre “Bioengineering” RAS, 2013.

  38. Khasanova, L.M., Il’ina, A.V., Varlamov, V.P., Sinitsyna, O.A., and Sinitsyn, A.P., Appl. Biochem. Microbiol., 2014, vol. 50, no. 4, pp. 381–386.

    Article  CAS  Google Scholar 

  39. Leppyanen, I.V., Artamonova, T.O., Lopatin, S.A., Varlamov, V.P., Tikhonovich, I.A., and Dolgikh, E.A., Ekol. Genet., 2013, vol. 11, no. 2, pp. 58–71.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Bioengineering Center, Russian Academy of Sciences, Moscow, 117312, Russia

    A. V. Il’ina & V. P. Varlamov

Authors
  1. A. V. Il’ina
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. P. Varlamov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. P. Varlamov.

Additional information

Original Russian Text © A.V. Il’ina, V.P. Varlamov, 2015, published in Prikladnaya Biokhimiya i Mikrobiologiya, 2015, Vol. 51, No. 1, pp. 5–14.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Il’ina, A.V., Varlamov, V.P. In vitro antitumor activity of heterochitooligosaccharides (Review). Appl Biochem Microbiol 51, 1–10 (2015). https://doi.org/10.1134/S0003683815010068

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0003683815010068

Keywords

Search

Navigation