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Absence of nucleophosmin leukaemic mutants in B and T cells from AML with NPM1 mutations: implications for the cell of origin of NPMc+ AML

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Acknowledgements

This work was supported by Associazione Italiana per la Ricerca sul Cancro (AIRC) and Fondazione Monte dei Paschi di Siena. NB is a recipient of a fellowship from Federazione Italiana per la Ricerca sul Cancro. We thank Debora Cecchini for performing FACS analysis of AML samples, Dr Geraldine Boyd for editing the manuscript and Mrs Claudia Tibidò for secretarial assistance. Brunangelo Falini applied for a patent on the clinical use of NPM mutants.

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Authors and Affiliations

  1. Institute of Haematology, University of Bari, Bari, Italy

    M P Martelli & G Specchia

  2. Section of Haematology and Immunology, University of Perugia, IBiT Foundation, Fondazione IRCCS Biotecnologie nel Trapianto, Perugia, Italy

    N Manes, V Pettirossi, R Pacini, R Mannucci, T Zei, N Bolli, I Nicoletti, M F Martelli & B Falini

  3. Institute of Haematology, University of Foggia, Foggia, Italy

    A Liso

  4. Istitute of Haematology, University of Catania, Catania, Italy

    F di Raimondo

Authors
  1. M P Martelli
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  2. N Manes
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  3. V Pettirossi
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  4. A Liso
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  5. R Pacini
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  6. R Mannucci
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  7. T Zei
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  8. N Bolli
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  9. F di Raimondo
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  10. G Specchia
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  11. I Nicoletti
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  12. M F Martelli
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  13. B Falini
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Corresponding author

Correspondence to B Falini.

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Supplementary Information accompanies the paper on the Leukemia website (http://www.nature.com/leu)

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Martelli, M., Manes, N., Pettirossi, V. et al. Absence of nucleophosmin leukaemic mutants in B and T cells from AML with NPM1 mutations: implications for the cell of origin of NPMc+ AML. Leukemia 22, 195–198 (2008). https://doi.org/10.1038/sj.leu.2404857

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  • DOI: https://doi.org/10.1038/sj.leu.2404857

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