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Reply to ‘TMEM230 variants in Parkinson’s disease’ and ‘Doubts about TMEM230 as a gene for parkinsonism’

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Fig. 1: Genome-wide Fastlink two-point LOD scores.

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Acknowledgements

This study was supported by the US National Institutes of Health (NS074366 and NS099623 to H.-X.D.). We thank A. H. Rajput for updating clinical information and X. Xia for sharing the unpublished whole-genome sequencing information.

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Authors and Affiliations

  1. Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

    Han-Xiang Deng & Teepu Siddique

  2. John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, USA

    Margaret A. Pericak-Vance

Authors
  1. Han-Xiang Deng
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  2. Margaret A. Pericak-Vance
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  3. Teepu Siddique
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Contributions

H.-X.D. and T.S. designed the research and performed the sequencing study. M.A.P.-V. performed the linkage study. H.-X.D., M.A.P.-V. and T.S. analyzed the data and wrote the paper.

Corresponding authors

Correspondence to Han-Xiang Deng or Teepu Siddique.

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Competing interests

The authors declare no competing interests.

Additional information

Editorial note: the journal apologizes to the authors for the unusual delay in the peer review and publication of this exchange of Correspondence and Reply.

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Supplementary Materials

Supplementary Note, Supplementary Figures 1–5 and Supplementary Tables 1 and 2

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Deng, HX., Pericak-Vance, M.A. & Siddique, T. Reply to ‘TMEM230 variants in Parkinson’s disease’ and ‘Doubts about TMEM230 as a gene for parkinsonism’. Nat Genet 51, 369–371 (2019). https://doi.org/10.1038/s41588-019-0355-5

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