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BIOPRINTING

Guiding tissue-scale self-organization

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A bioprinting approach that utilizes organoid-forming stem cells as a living ink within hydrogels guides tissue-scale self-organization to generate more realistic gastrointestinal and vascular tissue constructs.

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Fig. 1: Generation of large-scale tissues using a bioprinting-assisted tissue emergence approach.

Adapted with permission from ref. 2, Springer Nature Ltd.

References

  1. Simian, M. & Bissell, M. J. J. Cell Biol. 216, 31–40 (2017).

    Article  CAS  Google Scholar 

  2. Brassard, J. A., Nikolaev, M., Hübscher, T., Hofer, M. & Lutolf, M. P. Nat. Mater. https://doi.org/10.1038/s41563-020-00803-5 (2020).

  3. Watson, C. L. et al. Nat. Med. 20, 1310–1314 (2014).

    Article  CAS  Google Scholar 

  4. Reid, J. A., Mollica, P. A., Bruno, R. D. & Sachs, P. C. Breast Cancer Res. 20, 122 (2018).

    Article  Google Scholar 

  5. Bhattacharjee, T. et al. Sci. Adv. 1, e1500655 (2015).

    Article  Google Scholar 

  6. Highley, C. B., Rodell, C. B. & Burdick, J. A. Adv. Mater. 27, 5075–5079 (2015).

    Article  CAS  Google Scholar 

  7. Hinton, T. J. et al. Sci. Adv. 1, e1500758 (2015).

    Article  Google Scholar 

  8. Ronaldson-Bouchard, K. & Vunjak-Novakovic, G. Cell Stem Cell 22, 310–324 (2018).

    Article  CAS  Google Scholar 

  9. Nikolaev, M. et al. Nature 585, 574–578 (2020).

    Article  Google Scholar 

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Correspondence to Zev J. Gartner.

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Gartner, Z.J., Hu, J.L. Guiding tissue-scale self-organization. Nat. Mater. 20, 2–3 (2021). https://doi.org/10.1038/s41563-020-00885-1

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