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Optic ataxia errors depend on remapped, not viewed, target location

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Abstract

Optic ataxia is a disorder associated with posterior parietal lobe lesions, in which visually guided reaching errors typically occur for peripheral targets. It has been assumed that these errors are related to a faulty sensorimotor transformation of inputs from the 'ataxic visual field'. However, we show here that the errors observed in the contralesional field in optic ataxia depend on a dynamic gaze-centered internal representation of reach space.

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Figure 1: Fixation task and saccade–central viewing task.
Figure 2: Saccade–opposite field viewing task.

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Acknowledgements

We thank O.K. and C.F. for their participation and C. Urquizar, A. Blangero, M. Niemeier, J. Marotta and D. Pélisson for technical assistance and comments. This work was performed on the 'Mouvement et Handicap' platform (IFNL). This work was supported by Canadian Institutes of Health Research, Canada, and Institut National de la Santé et de la Recherche Médicale, Université Claude Bernard Lyon, and Programme Hospitalier de Recherche Clinique, France. J.D.C. is a Canada Research Chair.

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Author notes

  1. J D Crawford and Y Rossetti: These authors contributed equally to this work.

Authors and Affiliations

  1. Espace et Action, Institut National de la Santé et de la Recherche Médicale, U534, Institut Fédératif des Neurosciences Lyon, 16 avenue Doyen Lépine, Bron, 69676, France

    A Z Khan, L Pisella, A Vighetto, J Luauté, D Boisson, R Salemme & Y Rossetti

  2. Group for Action and Perception and Departments of Psychology, York Centre for Vision Research, Canadian Institutes of Health Research, Biology, Kinesiology and Health Sciences, York University, 4700 Keele Street, Toronto, M3J 1P3, Ontario, Canada

    A Z Khan & J D Crawford

  3. Hospices Civils de Lyon, Hôpital Neurologique Pierre Wertheimer, Hôpital Henry Gabrielle and Centre Hospitalier Lyon-Sud Jules Courmont, Quai des célestin, Lyon, 69002, France

    L Pisella, A Vighetto, F Cotton, J Luauté, D Boisson & Y Rossetti

Authors
  1. A Z Khan
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  2. L Pisella
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  3. A Vighetto
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  4. F Cotton
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  5. J Luauté
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  6. D Boisson
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  7. R Salemme
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  8. J D Crawford
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  9. Y Rossetti
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Corresponding author

Correspondence to Y Rossetti.

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The authors declare no competing financial interests.

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Khan, A., Pisella, L., Vighetto, A. et al. Optic ataxia errors depend on remapped, not viewed, target location. Nat Neurosci 8, 418–420 (2005). https://doi.org/10.1038/nn1425

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  • DOI: https://doi.org/10.1038/nn1425

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