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Single-particle tracking: connecting the dots

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Algorithms for analyzing single-particle tracking images to obtain the paths of individual particles are challenged by high-density data. Improvements in algorithms help to overcome these limitations.

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Figure 1: Schematic drawing of an SPT experiment.

References

  1. Baker, A. et al. Eur. Biophys. J. 36, 849–860 (2007).

    Article  CAS  Google Scholar 

  2. Brandenburg, B. & Zhuang, X.W. Nat. Rev. Microbiol. 5, 197–208 (2007).

    Article  CAS  Google Scholar 

  3. Janicki, S.M. & Spector, D.L. in Live Cell Imaging: A Laboratory Manual (eds. Goldman, R.D. and Spector, D.L.) 483–489 (Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, USA, 2005), .

    Google Scholar 

  4. Sergé, A., Bertaux, N., Rigneault, H. & Marguet, D. Nat. Methods 5, 687–694 (2008).

    Article  Google Scholar 

  5. Jaqaman, K. et al. Nat. Methods 5, 695–702 (2008).

    Article  CAS  Google Scholar 

  6. Manley, S. et al. Nat. Methods 5, 155–157 (2008).

    Article  CAS  Google Scholar 

  7. Giepmans, B.N.G., Adams, S.R., Ellisman, M.H. & Tsien, R.Y. Science 312, 217–224 (2006).

    Article  CAS  Google Scholar 

  8. Vogelsang, J. et al. Angew. Chem. Int. Edn. Engl. (in the press).

  9. Saxton, M.J. Biophys. J. 72, 1744–1753 (1997).

    Article  CAS  Google Scholar 

  10. Daumas, F. et al. Biophys. J. 84, 356–366 (2003).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Michael J. Saxton is in the Department of Biochemistry and Molecular Medicine, University of California, Davis, 1 Shields Ave., Davis, California 95616, USA. mjsaxton@ucdavis.edu,

    Michael J Saxton

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  1. Michael J Saxton
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Saxton, M. Single-particle tracking: connecting the dots. Nat Methods 5, 671–672 (2008). https://doi.org/10.1038/nmeth0808-671

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