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Marrow to muscle, fission versus fusion

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Bone marrow cells can reconstitute muscle, but which cells contribute to the process, and how do they do it? Two studies trace the journey of a single hematopoietic stem cell into muscle tissue (pages 1520–1527 and 1528–1532).

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Figure 1: Different mechanisms by which transplanted stem cells potentially participate in regenerative myogenesis.

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Rudnicki, M. Marrow to muscle, fission versus fusion. Nat Med 9, 1461–1462 (2003). https://doi.org/10.1038/nm1203-1461

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