The only targets for clinical treatment of herpes simplex virus infections have been the viral enzymes thymidine kinase and DNA polymerase. Now, animal experiments show the healing benefits of new antiherpes drugs that act on the viral helicase–primase complex and appear superior to the standard treatment, acyclovir.
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Crumpacker, C., Schaffer, P. New anti-HSV therapeutics target the helicase–primase complex. Nat Med 8, 327–328 (2002). https://doi.org/10.1038/nm0402-327
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DOI: https://doi.org/10.1038/nm0402-327
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