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Lethal H5N1 influenza viruses are not resistant to interferon action in human, simian, porcine or chicken cells

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Figure 1: Sensitivity of A/PR8/8/34 (H1N1) and H5N1-NS reassortant viruses to the action of IFNs.
Figure 2: Sensitivity to cytokine action of several influenza viruses used in the study by Seo et al.1.

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References

  1. Seo, S.H., Hoffman, E. & Webster, R.G. Nat. Med. 8, 950–954 (2002).

    Article  CAS  Google Scholar 

  2. Cauthen, A.N., Swayne, D.E., Sekellick, M.J., Marcus, P.I. & Suarez, D.L. J. Virol. 81, 1838–1847 (2007).

    Article  CAS  Google Scholar 

  3. Marcus, P.I., Ngunjiri, J.M., Sekellick, M.J., Wang, L. & Lee, C.-W. J. Virol. 84, 10974–10981 (2010).

    Article  CAS  Google Scholar 

  4. Sekellick, M.J., Carra, S.A., Bowman, A., Hopkins, D.A. & Marcus, P.I. J. Interferon Cytokine Res. 20, 963–970 (2000).

    Article  CAS  Google Scholar 

  5. Webster, R.G., Bean, W.J., Gorman, O.T., Chambers, T.M. & Kawaoka, Y. Microbiol. Rev. 56, 152–179 (1992).

    CAS  PubMed  PubMed Central  Google Scholar 

  6. Hayman, A. et al. J. Virol. 81, 2318–2327 (2007).

    Article  CAS  Google Scholar 

  7. Haasbach, E., Droebner, K., Vogel, A.B. & Planz, O. J. Interferon Cytokine Res. 31, 515–525 (2011).

    Article  CAS  Google Scholar 

  8. Szretter, K.J. et al. J. Virol. 83, 5825–5834 (2009).

    Article  CAS  Google Scholar 

  9. Marcus, P.I. & Yoshida, I. J. Cell. Physiol. 143, 416–419 (1990).

    Article  CAS  Google Scholar 

  10. Silversides, D.W., Music, N., Jaques, M., Gagnon, C.A. & Webby, R. J. Virol. 84, 5454–5455 (2010).

    Article  CAS  Google Scholar 

  11. Herfst, S. et al. Science 336, 1534–1541 (2012).

    Article  CAS  Google Scholar 

  12. Imai, M. et al. Nature 486, 420–428 (2012).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by a donation to the Virus and Interferon Research Laboratory (P.I.M. and M.J.S.), by the US National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Department of Health and Human Services, contract number HSN266200700005C and by the American Lebanese Syrian Associated Charities (R.G.W. and S.S.-C.).

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Author notes

  1. Kareem N Mohni

    Present address: Current address: Department of Molecular, Microbial and Structural Biology, University of Connecticut Health Center, Farmington, Connecticut, USA.,

Authors and Affiliations

  1. Department of Molecular and Cell Biology, Virus and Interferon Research Laboratory, University of Connecticut, Storrs, Connecticut, USA

    John M Ngunjiri, Kareem N Mohni, Margaret J Sekellick & Philip I Marcus

  2. Division of Virology, Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA

    Stacey Schultz-Cherry & Robert G Webster

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  1. John M Ngunjiri
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  2. Kareem N Mohni
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  5. Robert G Webster
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  6. Philip I Marcus
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Correspondence to Philip I Marcus.

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Ngunjiri, J., Mohni, K., Sekellick, M. et al. Lethal H5N1 influenza viruses are not resistant to interferon action in human, simian, porcine or chicken cells. Nat Med 18, 1456–1457 (2012). https://doi.org/10.1038/nm.2879

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