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Capturing condensin in chromosomes

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A new study uses a Hi-C technique to demonstrate that condensin has a major role in remodeling interphase chromatin into mitotic chromosomes. This study provides insight into the mechanism whereby a centimeters-long DNA molecule is folded into a micrometers-long rod-shaped chromosome.

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Figure 1: Chromosome organization.

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Authors and Affiliations

  1. the Chromosome Dynamics Laboratory, RIKEN, Wako, Japan

    Tatsuya Hirano

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  1. Tatsuya Hirano
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Correspondence to Tatsuya Hirano.

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The author declares no competing financial interests.

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Hirano, T. Capturing condensin in chromosomes. Nat Genet 49, 1419–1420 (2017). https://doi.org/10.1038/ng.3962

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