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BLOSUM62 miscalculations improve search performance

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Figure 1: Performance difference between BLOSUM62 and RBLOSUM64 as assessed by pairwise sequence comparison evaluation (PSCE) tools4.

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Author notes

  1. Mark P Styczynski

    Present address: Current address: Broad Institute, Room 6175X, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.,

  2. Mark P Styczynski and Kyle L Jensen: These authors contributed equally to this work.

Authors and Affiliations

  1. Department of Chemical Engineering, Massachusetts Institute of Technology, Room 56-469c, 77 Massachusetts Avenue, Cambridge, 02139, Massachusetts, USA

    Mark P Styczynski & Gregory Stephanopoulos

  2. Department of Plant Sciences, Public Intellectual Property Resource for Agriculture, University of California, One Shields Avenue, Plant Reproductive Biology Building–Mail Stop 5, Davis, 95616, California, USA

    Kyle L Jensen

  3. Harvard-MIT Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, 02139, Massachusetts, USA

    Kyle L Jensen

  4. IBM Research Division, Thomas J. Watson Research Center, 1101 Kitchawan Road, PO Box 218, Yorktown Heights, 10598, New York, USA

    Isidore Rigoutsos

Authors
  1. Mark P Styczynski
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  2. Kyle L Jensen
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  3. Isidore Rigoutsos
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  4. Gregory Stephanopoulos
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Styczynski, M., Jensen, K., Rigoutsos, I. et al. BLOSUM62 miscalculations improve search performance. Nat Biotechnol 26, 274–275 (2008). https://doi.org/10.1038/nbt0308-274

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