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Stem cells

Reprogramming in situ

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Cellular reprogramming to a stem-cell state has now been achieved in tissues of genetically engineered mice. This work signals a future for regenerative medicine in which tissue fates might be manipulated in living organisms. See Article p.340

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Figure 1: Pluripotent stem cells and their potential.

Notes

  1. *This article and the paper under discussion1 were published online on 11 September 2013.

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Authors and Affiliations

  1. Division of Pediatric Hematology and Oncology, at the Harvard Stem Cell Institute and in the Department of Biological Chemistry and Molecular Pharmacology, Alejandro De Los Angeles and George Q. Daley are in the Stem Cell Transplantation Program, Children's Hospital Boston and Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA. They are also at the Howard Hughes Medical Institute, Harvard Medical School, Boston.,

    Alejandro De Los Angeles & George Q. Daley

Authors
  1. Alejandro De Los Angeles
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  2. George Q. Daley
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Correspondence to George Q. Daley.

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De Los Angeles, A., Daley, G. Reprogramming in situ. Nature 502, 309–310 (2013). https://doi.org/10.1038/nature12559

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