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Biological techniques

An embryonic view of tumour development

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A genome-wide screen of developing mouse embryos, performed using RNA-interference techniques, finds new suspects in skin cancer. But some factors seem to have opposing roles in cancer and normal-tissue maintenance. See Article p.185

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Figure 1: Role of β-catenin in normal and cancer-prone skin cells.

Notes

  1. *This article and the paper under discussion1 were published online on 14 August 2013.

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Authors and Affiliations

  1. Pawel J. Schweiger and Kim B. Jensen are at the Biotech Research and Innovation Center, University of Copenhagen, DK-2200 Copenhagen N, Denmark.,

    Pawel J. Schweiger & Kim B. Jensen

  2. K.B.J. is also at the Wellcome Trust and Medical Research Council Cambridge Stem Cell Institute, Cambridge, UK.,

    Kim B. Jensen

Authors
  1. Pawel J. Schweiger
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  2. Kim B. Jensen
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Correspondence to Kim B. Jensen.

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Schweiger, P., Jensen, K. An embryonic view of tumour development. Nature 501, 171–172 (2013). https://doi.org/10.1038/nature12547

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