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Regenerative biology

Heartbroken embryos heal

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An area of injured heart in zebrafish embryos repairs itself using cells from neighbouring areas. The regenerating cells seem to originate from an intermediate progenitor-cell population. See Letter p.497

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Figure 1: Spontaneous repair and regeneration of the heart.

Notes

  1. *This article and the paper under discussion2 were published online on 19 June 2013.

References

  1. Morgan, T. H. in Regeneration (Macmillan, 1901).

    Book  Google Scholar 

  2. Zhang, R. et al. Nature 498, 497–501 (2013).

    Article  ADS  CAS  Google Scholar 

  3. Poss, K. D., Wilson, L. G. & Keating, M. T. Science 298, 2188–2190 (2002).

    Article  ADS  CAS  Google Scholar 

  4. Kikuchi, K. & Poss, K. D. Annu. Rev. Cell. Dev. Biol. 28, 719–741 (2012).

    Article  CAS  Google Scholar 

  5. Jopling, C. et al. Nature 464, 606–609 (2010).

    Article  ADS  CAS  Google Scholar 

  6. Laugwitz, K. L. et al. Nature 433, 647–653 (2005).

    Article  ADS  CAS  Google Scholar 

  7. Moretti, A. et al. Cell 127, 1151–1165 (2006).

    Article  CAS  Google Scholar 

  8. Bu, L. et al. Nature 460, 113–117 (2009).

    Article  ADS  CAS  Google Scholar 

  9. Song, K. et al. Nature 485, 599–604 (2012).

    Article  ADS  CAS  Google Scholar 

  10. Qian, L. et al. Nature 485, 593–598 (2012).

    Article  ADS  CAS  Google Scholar 

  11. Inagawa, K. et al. Circ. Res. 111, 1147–1156 (2012).

    Article  CAS  Google Scholar 

  12. Fernandez, E., Siddiquee, Z. & Shohet, R. V. Dev. Dyn. 221, 302–310 (2001).

    Article  CAS  Google Scholar 

  13. Mahmoud, A. I. et al. Nature 497, 249–253 (2013).

    Article  ADS  CAS  Google Scholar 

  14. Drenckhahn, J. D. et al. Dev. Cell 4, 521–533 (2008).

    Article  Google Scholar 

  15. Yang, L. et al. Nature 453, 524–528 (2008).

    Article  ADS  CAS  Google Scholar 

  16. Mummery, C. L., Davis, R. P. & Krieger, J. E. Sci. Transl. Med. 2, 27 (2010).

    Article  Google Scholar 

  17. Zaidi, S. et al. Nature 498, 220–223 (2013).

    Article  ADS  CAS  Google Scholar 

  18. Stevens, K. N. et al. PLoS ONE 5, e10855 (2010).

    Article  ADS  Google Scholar 

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Authors and Affiliations

  1. Kenneth R. Chien is in the Department of Cell and Molecular Biology and Medicine, Karolinska Institutet, 17177 Stockholm, Sweden, and at Harvard University, Cambridge, Massachusetts, USA.,

    Kenneth R. Chien

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  1. Kenneth R. Chien
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Correspondence to Kenneth R. Chien.

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Chien, K. Heartbroken embryos heal. Nature 498, 439–440 (2013). https://doi.org/10.1038/nature12262

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