The discovery that schistosomes possess adult stem cells could explain the long-term persistence of these parasitic worms in humans. Targeting a protein produced by the cells might damage schistosome defences. See Letter p.476
Notes
*This article and the paper under discussion2 were published online on 20 February 2013.
References
King, C. H. & Dangerfield-Cha, M. Chronic IIlness 4, 65–79 (2008).
Collins, J. J. III et al. Nature http://dx.doi.org/10.1038/nature11924 (2013).
Gotoh, N. Curr. Stem Cell Res. Ther. 4, 9–15 (2009).
Doenhoff, M. J. et al. Parasitology 136, 1825–1835 (2009).
Erasmus, D. A., Popiel, I. & Shaw, J. R. Parasitology 84, 283–287 (1982).
Protasio, A. V. et al. PLoS Negl. Trop. Dis. 6, e1455 (2012).
Krautz-Peterson, G., Bhardwaj, R., Faghiri, Z., Tararam, C. A. & Skelly, P. J. Parasitology 137, 485–495 (2010).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Pearce, E. Rejuvenation through stem cells. Nature 494, 438–439 (2013). https://doi.org/10.1038/nature11953
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature11953
- Springer Nature Limited