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Evolutionary genomics

Codon volatility does not detect selection (reply)

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Abstract

Plotkin et al. reply - The criticisms of our results1 by Hahn et al.2, Nielsen and Hubisz3, and Chen, Emerson and Martin4 fall into three categories: the formal justification for our method, the potential for confounding factors, and the interpretation of our empirical results.

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References

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Authors and Affiliations

  1. Harvard Society of Fellows, 7 Divinity Avenue, Cambridge, 02138, Massachusetts, USA

    J. B. Plotkin

  2. Department of Ecology and Evolutionary Biology, Princeton University, Princeton, 08540, New Jersey, USA

    J. Dushoff

  3. Fogarty International Center, National Institutes of Health, Bethesda, 20892, Maryland, USA

    J. Dushoff

  4. Department of Molecular and Cell Biology, University of California, Berkeley, 94720, California, USA

    H. B. Fraser

Authors
  1. J. B. Plotkin
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  2. J. Dushoff
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  3. H. B. Fraser
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Correspondence to J. B. Plotkin.

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Plotkin, J., Dushoff, J. & Fraser, H. Codon volatility does not detect selection (reply). Nature 433, E7–E8 (2005). https://doi.org/10.1038/nature03224

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