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Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: AKT1 and DAT1 genotype modulates the effects of δ-9-tetrahydrocannabinol on midbrain and striatal function

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Acknowledgements

Dr Sagnik Bhattacharyya was supported by a Joint MRC/Priory Clinical research training fellowship from the Medical Research Council, UK. The authors also acknowledge financial support from Generalitat de Catalunya (SGR 2009/1435) and the National Institute for Health Research (NIHR) Specialist Biomedical Research Centre for Mental Health award to the South London and Maudsley NHS Foundation Trust and the Institute of Psychiatry, King's College London, and the ongoing support of the Wellcome Trust and EPSRC toward the Medical Engineering Centre within King's College London.

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Authors and Affiliations

  1. Department of Psychosis Studies, King's College London, Institute of Psychiatry, De Crespigny Park, London, UK

    S Bhattacharyya, Z Atakan, J Kambeitz, D Prata & P K McGuire

  2. IMIM-Hospital del Mar and Psychiatric Department, Department of Psychiatry and Clinical Psychobiology, Pharmacology Research Unit, ICN, Hospital Clinico, IDIBAPS, CIBERSAM, University of Barcelona, Barcelona, Spain

    R Martin-Santos

  3. Department of Neurology, Psychiatry and Medical Psychology, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Sao Paulo, Brazil

    J A Crippa

  4. Department of Neuroimaging, Centre for Neuroimaging Sciences, PO Box 089, King's College London, Institute of Psychiatry, De Crespigny Park, London, UK

    S Williams & M Brammer

  5. Social, Genetic & Developmental Psychiatry Centre, PO Box 082, King's College London, Institute of Psychiatry, De Crespigny Park, London, UK

    D A Collier

Authors
  1. S Bhattacharyya
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  2. Z Atakan
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  3. R Martin-Santos
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  5. J Kambeitz
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  6. D Prata
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  7. S Williams
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  8. M Brammer
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  9. D A Collier
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  10. P K McGuire
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Corresponding author

Correspondence to S Bhattacharyya.

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Bhattacharyya, S., Atakan, Z., Martin-Santos, R. et al. Preliminary report of biological basis of sensitivity to the effects of cannabis on psychosis: AKT1 and DAT1 genotype modulates the effects of δ-9-tetrahydrocannabinol on midbrain and striatal function. Mol Psychiatry 17, 1152–1155 (2012). https://doi.org/10.1038/mp.2011.187

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