Abstract
Fourteen patients with advanced breast cancer were treated with the ribonucleotide reductase inhibitor didox 6 g m-2 given by intravenous infusion over 36 h every 3 weeks. None responded and toxicity was minimal. Possibilities for the more effective use of this agent are discussed.
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Rubens, R., Kaye, S., Soukop, M. et al. Phase II trial of didox in advanced breast cancer. Br J Cancer 64, 1187–1188 (1991). https://doi.org/10.1038/bjc.1991.488
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DOI: https://doi.org/10.1038/bjc.1991.488
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