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Cancer

Entangled pathways

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A medley of molecules, and the interactions between them, mediate cancer. The latest news is that the enzyme CDK8 orchestrates cross-talk between two signalling pathways that are frequently deregulated in human cancers.

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Figure 1: Cross-talk between signalling pathways in colorectal cancer2,3.

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Bernards, R. Entangled pathways. Nature 455, 479–480 (2008). https://doi.org/10.1038/455479a

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